autoimmune pathology of type 1 diabetes

... Gender, = male Diabetes duration, years NA 1. 10 (1. 07 - 1. 13) NA 1. 04 (1. 01 - 1. 06) NA 1. 12 (1. 09 - 1. 15) NA 1. 11 (1. 08 - 1. 13) 0.86 (0.64 - 1. 15) 0.99 (0.98 - 1. 01) 1. 00 (0.98 - 1. 01) Model Age ... 1. 53 (1. 01 - 2.33) 1. 15 (0. 81 - 1. 63) 1. 44 (1. 06 - 1. 97) NA NA NA NA 0.84 (0.65 - 1. 08) Weak SOC 1. 97 (1. 15 - 3.05) 1. 03 (0.65 - 1. 62) 1. 39 (0.85 - 2.27) 1. 20 (0.80 - 1. 81) 1. 43 (1. 04 - 1. 95) ... NA NA 0.83 (0.64 - 1. 08) Model Weak SOC Gender, = male Model Diabetes duration, years 1. 07 (1. 05 - 1. 09) 1. 04 (1. 02 - 1. 06) 1. 11 (1. 09 - 1. 13) 1. 10 (1. 08 - 1. 12) 0.99 (0.98 - 1. 00) Age at onset,...

Ngày tải lên: 20/06/2014, 15:20

... complication of diabetes mellitus This case illustrates the importance of checking blood sugar levels of patients with non-healing corneal ulcers to rule out the possibility of undiagnosed diabetes ... (pCO2) of 44.7mmHg, and a partial pressure of oxygen (pO2) of 89.5 mmHg She was transferred to the care of the medical team and a diagnosis of type diabetes was made She was started on treatment ... Decreased penetration of anchoring fibrils into the diabetic stroma A morphometric analysis Arch Ophthalmol 19 89, 10 7 :15 20 -15 23 Sakamoto A, Sasaki H, Kitagawa K: Successful treatment of diabetic keratopathy...

Ngày tải lên: 10/08/2014, 22:20

... parents (99) Offspring ( 913 ) Control ( 71) 10 .1 3.5 (32) 1. 3 (11 ) Jaeger et al 20 01 Germany (7) IgA-tTG, IgA &IgG-AGA Diabetic children (19 7) Parent, sibling and offspring (882) Control (15 0) 16 .8 7.3 ... Parent (69) Offspring (58) Control (50) Matteucci et al 20 01 Italy (14 ) Not et al 20 01 Italy (8) AEA; Biopsy Williams et al 20 01 UK (10 ) IgA-AEA; IgA-tTG 34 14 5.7 (28) 1. 9 (16 ) 0.25 (10 ) Diabetic ... Parent (8 71) and sibling (5 71) Control (347) 1. 6 (9) *

Ngày tải lên: 05/03/2014, 12:20

... N Davis 73 10 1 11 5 Fueling the Athlete with Type Diabetes Carin Hume 15 1 Diabetes and Doping Richard I.G Holt 16 7 Synthesis of Best Practice Ian Gallen 19 3 10 The Athlete’s ... 19 94;267:E 411 – 21 130 Niijima A Glucose-sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea-pig J Physiol 19 82;332: 315 –23 13 1 Smith D, Pernet A, Reid H, et al The role of ... Physiol 19 94;77 :15 37– 41 162 Tabata I, Ogita F, Miyachi M, Shibayama H Effect of low blood glucose on plasma CRF, ACTH, and cortisol during prolonged physical exercise J Appl Physiol 19 91; 71: 18 07 12 ...

Ngày tải lên: 14/03/2014, 09:20

... 20. 91 (12 .43) 12 .0 210 214 89 (42.2) 10 1 (47.9) 21 (10 .0) 19 5 (92.9) 4.0 (1. 0–5.0) 215 213 215 214 88 (40.7) 73 (33.8) 55 (22.5) 40 (18 .5) 216 216 216 216 216 82 (38.0) 56 (25.9) 44 (20.4) 34 (15 .7) ... ≤ $10 000 $10 000 – 29 999 $30 000 – 49 999 $50 000 – 69 999 ≥ $70 000 n Total* 215 216 37 .13 (14 .28) 12 7 (58.8) 216 69 ( 31. 9) 13 1 (60.6) 13 (6.0) (1. 4) 216 16 (7.4) 42 (19 .4) 43 (19 .9) 41 (19 .0) ... (19 .0) 27 (12 .5) 40 (8.5) (3.2) 216 12 6 (58.3) 11 (5 .1) 18 (8.3) 30 (13 .9) 16 (7.4) 15 (6.9) 19 6 19 (9.7) 44 (22.4) 37 (18 .9) 36 (18 .4) 60 (30.6) *n (%) unless otherwise specified [10 ] The oblique...

Ngày tải lên: 20/06/2014, 15:20

... 28/44 (64) 14 /16 (88) 21/ 28 (75) 12 /12 (10 0) 12 /12 (10 0) 11 3 0.43-0.65 0.58-0.83 0.54-0. 71 0.75-0.84 0.69-0.86 11 /11 (10 0) 4/4 (10 0) 7/7 (10 0) 3/3 (10 0) 3/3 (10 0) 0.002-0.42 0 .19 -0.57 0. 01- 0.54 ... (79) 15 /15 (10 0) 14 /15 (93) 13 /15 (87) 11 3 0.37-0.66 0.63-0.75 0.58-0.82 0.70-0.85 0.76-0.87 10 /11 (90. 91) 4/4 (10 0) 7/7 (10 0) 3/3 (10 0) 3/3 (10 0) 0.0 01- 0.42 0.26-0.74 0 .16 -0.62 0.22-0. 61 0.25-0.50 ... 5. 61 (1, 292) 0. 019 Psychosocial health 15 94 66. 81 13 . 81 0.79 200 74 .15 16 .59 12 .13 (1, 292) 0.0 01 PedsQLTM 3.0 Diabetic Module Child self-report Diabetes symptoms 11 94 59. 21 14 .46 0.74 Treatment...

Ngày tải lên: 20/06/2014, 15:20

... http://www.annals-general-psychiatry.com/content/6 /1/ 25 12 13 14 15 16 17 18 19 20 21 and improving the standard of care J Clin Psychopharmacol 2004, 24(5 Suppl 1) :S7-S14 Hirschfeld RM, Kasper S: A review of the evidence for ... The patient was a 55-year-old married female, mother of two healthy grown-up children, with a history of type- 1 DM since the age of 11 For her diabetes, she was initially treated with insulin (Novolente) ... the treatment of bipolar disorder in children and adolescents Am J Psychiatry 2006, 16 3 :11 79 -11 86 Suppes T, Kelly DI, Hynan LS, Snow DE, Sureddi S, Foster B, Curley E: Comparison of two anticonvulsants...

Ngày tải lên: 08/08/2014, 23:20

... co-occurrence of autoimmune thyroiditis and type diabetes mellitus in our patient was coincidental; however, the elevated risk of other types of autoimmune diabetes in individuals with type diabetes ... Chiarelli F: The effect of subclinical hypothyroidism on metabolic control in children and adolescents with type diabetes mellitus Diabet Med 2002, 19 :70-73 doi :10 .11 86 /17 52 -19 47-5-277 Cite this ... effect of methimazole treatment Amory and Hirsch Journal of Medical Case Reports 2 011 , 5:277 http://www.jmedicalcasereports.com/content/5 /1/ 277 Page of 16 35 TSH (mIU/ml) Free Thyroxine 14 30...

Ngày tải lên: 10/08/2014, 23:21

... blindness 0 .10 1 0.057 0 .15 6 Hoerger et al [16 ,17 ] Diabetes with no complications to CHD 0.0 31 0. 018 0.048 Hoerger et al [16 ,17 ] Reference Subsequent LEA 0 .11 0 0.062 0 .16 9 Hoerger et al [16 ,17 ] Diabetes ... 2 011 Accepted: 14 September 2 011 Published: 14 September 2 011 References American Diabetes Association: Economic Costs of Diabetes in the U.S in 2007 Diabetes Care 2008, 31( 3):596- 615 The Diabetes ... ADA [1] ESRD 36,370 26,377 47,708 ADA [1] LEA 50 ,15 0 36,5 41 65,798 ADA [1] Nephropathy 20 ,16 1 14 , 614 26,643 ADA [1] Neuropathy 25,075 18 ,226 33,004 ADA [1] Retinopathy 4,956 3,578 6,489 ADA [1] ...

Ngày tải lên: 13/08/2014, 11:22

... cells.…………….… 11 2 4 .1. 4 Immaturity of encapsulated MEPI -1 cells…….………………… 11 3 4 .1. 5 Summary of transplantation of microencapsulated MEPI -1 cells…… .11 6 4.2 Restoration of MafA in MEPI -1 cells………………….……….……… ... mice………… 14 1. 2.5 Microencapsulation techniques……………………………………… 15 1. 2.5 .1 Ratinale of encapsulation of cells……………………………… 15 1. 2.5.2 Principle and application of encapsulation……………………… 16 1. 3 Roles of ... ……………… … 10 9 4 .1. 3.2 The permeability of transplanted microcapsule……………… 11 0 4 .1. 3.3 The immune reaction after microcapsule transplantation …… 11 1 4 .1. 3.4 Behaviors of microencapsulated MEPI -1 cells.…………….… 11 2...

Ngày tải lên: 11/09/2015, 09:58

... 2.3 (95% CI 1. 6 to 3.4) - sepsisa 13 5.0 (95% CI 2.0 to 12 .5) - ACSb 10 6.0 (95% CI 1. 9 to 18 .5) all patients New Type DM - other diagnoses 10 6.0 (95% CI 2.0 to 18 .1) 33 (17 .1% ) 14 (3.5%) 5.6 ... sepsisa 18 18 2 .1 (95% CI 1. 3 to 4 .1) - ACSb 19 17 2.6 (95% CI 1. 4 to 4.6) - ACSb - other diagnoses all patients New IFG or IGT - other diagnoses 10 14 1. 9 (95% CI 0.9 to 3.9) 47 (24.4%) 49 (12 .3%) ... 0.0 01 - enteral nutrition only 703 (68.3%) 248 (68.8%) 455 (68 .1% ) P = 0.823 - total parenteral or combination 326 ( 31. 7%) 11 2 ( 31. 1%) 214 ( 31. 9%) Caloric intake (% of target) 85% (66 to 11 5)...

Ngày tải lên: 25/10/2012, 10:02

... N=6 419 1 RR2 95% CI P trend 1. 00 1. 21 1.03 -1. 41 0.02 1. 00 1. 25 1. 18 1. 06 -1. 47 0.99 -1. 37 1. 00 1. 22 1. 17 1. 23 1. 03 -1. 44 0.99 -1. 39 1. 02 -1. 48 1. 00 1. 01 0.95 0.90 -1. 14 0.79 -1. 16 1. 00 1. 25 1. 13 1. 09 -1. 43 ... 1. 00 1. 15 1. 01- 1.32 249 838 882 1. 00 1. 20 1. 10 1. 04 -1. 38 0.95 -1. 27 Types of product None One type Two Types Three Types 249 716 628 376 1. 00 1. 15 1. 15 1. 14 0.99 -1. 33 0.99 -1. 34 0.96 -1. 34 Smoked ... month >once per month 13 39 488 14 2 1. 00 1. 02 0.93 0.92 -1. 14 0.78 -1. 11 Salted/Processed Meat Never once per month 364 11 94 411 1. 00 1. 20 1. 07 1. 06 -1. 35 0.93 -1. 24 P trend 0.04 0.67...

Ngày tải lên: 31/10/2012, 16:49

... 81. 9 74.2 73 73.4 73.2 72.2 72.6 72.5 66.6 70.8 12 72 14 28 14 07 14 13 14 22 14 13 14 22 14 19 14 22 14 22 14 19 14 19 14 18 12 36 13 20 21. 5 70.7 73.9 61. 9 82.9 88 .1 84.4 82.2 83.3 83.3 82.4 82.4 82.4 74.4 80.2 ... cnr1b, CAAB 010 014 84 .1; Danio rerio, NW_634056 .1; Mus musculus, NT _10 9 315 .2; Rattus norvegicus, NW_047 711 .2; Felis catus, NM_0 010 093 31. 1; Pan troglodytes, NW _10 7960 .1; Homo sapiens, NT_086697 .1 ... 378 528 (TM1–7) comprise amino acid residues 11 0 13 2 (TM1), 14 5 16 7 (TM2), 18 2–204 (TM3), 225–247 (TM4), 267–289 (TM5), 337–359 (TM6), and 369–3 91 (TM7); the four cytoplasmic domains (CD1–4) comprise...

Ngày tải lên: 30/03/2014, 08:20

... 1. 4 ab 2.64 0.38 ab 64.4 10 .1 ab 43.3(42.6, 60.4) 10 6 (10 5, 16 1) 5.9 4 .14 b 17 .1 3 .1 n 20 20 20 20 20 17 19 10 19 T1DM +DC 16 .4 (15 .1, 17 .6)a 10 .0(7.9, 12 .9) 10 .4 1. 4a 3.06 0.48a 71. 8 11 .6 ... TGF-beta1 (ng/ml) VCAM -1 (ng/ml) a b CTRL 9.0(6 .1, 14.0) 5.0 0.3 1. 67 0. 31 54.9 9.9 58.8(52.0, 71. 8) 10 0(88, 11 0) 3.30 3. 41 12.6 3.7 n 26 18 24 22 11 10 15 T1DM -DC 14 .4 (12 .4, 17 .9)ab 6(5.5, 8 .1) b ... Pathogenesis, and Alternative Treatments 12 00 VCAM -1 (ng/ml) 11 00 10 00 900 800 700 600 10 11 12 HbA1cA (%) Fig The linear correlation between VCAM -1 and HbA1cA DD HbA1cA HbA1cP FAM (yrs.) Age (yrs.) 0.205...

Ngày tải lên: 27/06/2014, 17:20

... NCT00607230 NCT 011 156 21 NCT00279 318 NCT00333554 NCT 010 55080 NCT00607230 NCT0 014 1986 NCT0 013 1755 NCT00024 518 NCT00 711 503 NCT00645840 NCT00947427 NCT 013 193 31 NCT00279305 NCT00 214 214 NCT00 515 099 NCT00505375 ... 2005), Vol .11 7, No .1, pp 31- 35, ISSN 15 21- 6 616 Pittas, A.G & Dawson-Hughes, B (2 010 ) Vitamin D and diabetes The Journal of Steroid Biochemistry and Molecular Biology, (July 2 010 ), Vol .12 1, No .1- 2, ... 2 010 ) Vol .10 , No .12 , pp 14 91- 1495, ISSN 15 67-5769 Boettler, T & von Herrath, M (2 011 ) Protection against or triggering of Type diabetes? Different roles for viral infections Expert Review of...

Ngày tải lên: 27/06/2014, 17:20

... 6p 21 HLA 0.02-49.2 6q15 6q22.32 6q23.3 6q25.3 7p15.2 7p12 .1 9p24.2 10 p15 .1 10p15 .1 10q22.3 10 q23. 31 11p15.5 12 p13. 31 12q13.3 12 q13.2 12 q24 .12 13 .32.3 14 q24 .1 14q32.2 14 q32.2 15 q14 15 q25 .1 16p13 .13 ... 1p13.2 1q 31. 2 1q32 .1 2q 11. 2 2q24.2 2q32.2 2q33.2 3p 21. 31 4p15.2 4q27 PTPN22 RGS1 IL20-IL10-IL19 Several IFIH1 STAT4 CTLA4 CCR5 AC 111 003 .1 IL2-IL 21 2.05 0.89 0.84 -0.86 1. 10 0.82 0.85 1. 09 1. 13 ... _3296043 _10 G (0.48) 6q23.3 TNFAIP3 rs1049 919 4 C _15 755 81_ 10 T (0.32) 9q33.2 TRAF1 rs2269059 C 15 875924 _10 A (0.07) 11 p15.5 INS rs689 C _12 23 317 _10 A (0.28) 12 p13. 31 CLEC2D rs 110 52552 C 3 216 9467 _10 ...

Ngày tải lên: 27/06/2014, 17:20

... simuation, pp 1- 14, ISSN 0378 4754,, doi: 10 .10 16/j.matcom.2 010 .10 .024 Behl, G F E., Copeland, J A., Wiggins, J (2004) The District of Columbia Diabetes ... 11 , (2003), pp 310 2– 311 0, Online ISSN 19 35-5548 HER (20 01) Human energy requirements, Report of a Joint FAO/WHO/UNU Expert Consultation, Rome, 17 -24 October 20 01, ISBN 92-5 -10 5 212 -3, ISSN 18 13-3932, ... A K (2 011 ) Prevalence of Prediabetes in School-Going Children, Indian Pediatrics, Vol 48, 2 011 , pp 295-299, ISSN 0 019 -60 61 NDS (2 011 ) National Diabetes Statistics, 2 011 , U.S Department of Health...

Ngày tải lên: 27/06/2014, 18:20

... Investigation Vol 11 2, No 12 (December 2003), pp 17 96 -18 08 Wendorf M & Goldfine ID (19 91) Archaeology of NIDDM Excavation of the ‘thrifty’ genotype Diabetes Vol 40, No (February 19 91) , pp 16 1-65 Weyer ... Diabetes Vol 56, No (April 2007), pp 9 01- 11 Hotamisligil GS (19 99) Mechanism of TNF-alpha induced insulin resistance Experimental and Clinical Endocrinology & Diabetes Vol 10 7, No 2, pp .11 9 -12 5 ... while reducing TNFα levels (Pedersen et al., 2007) Myokine Locus IL-6 7p 21 IL-8 4q12q13 IL -15 4q 31 IL -10 1q31q32 IL-1ra 2q14.2 Effect Anti-inflammatory when secreted before TNF-α (Carey et al.,...

Ngày tải lên: 27/06/2014, 19:20

... coordination of ATP and subsequent trans autophosphorylation of Tyr 114 6, Tyr 115 0 and Tyr 115 1 within the activation loop of the tyrosine kinase domain (Hubbard, 2004) 12 Medical Complications of Type Diabetes ... FPG of 11 0 -12 5 mg/dl in 19 97 In 19 97, the FPG cut-off value to diagnose diabetes was lowered from 14 0 to 12 6 mg/dl It was evident that the rationale for lowering the cut-off FPG levels (12 6 mg/dl ... American Diabetes Association (19 97) Report of the Expert Committee on the diagnosis and Classification of Diabetes Mellitus Diabetes Care, Vol 20, No.7, (July 19 97), pp 11 83 -11 97, ISSN: 014 9-5992...

Ngày tải lên: 28/06/2014, 05:20