area of forests important for the provision of amenities

... were constructed by use of the EcoRV and SacI sites in the cDNA and were then used to transform 293-cells The region responsible for the different degree of association of the human and murine enzyme ... about one tenth of the specific activity of the oligomeric complex [15] For the recombinant human enzyme the nonassociated form also appeared to be dimers of the 138 kDa subunit, since their Mr was ... there is a cluster of amino-acid differences in the C-terminal part of the enzyme (Fig 2A) where 13 of 44 amino acids are different Therefore, chimeric enzymes with the N-terminal part from the...

Ngày tải lên: 21/02/2014, 15:20

... 3222 in the presence or absence of tunicamycin Drug treatments resulted in the accumulation of forms of the mutant proteins that were of lower apparent molecular mass and of similar size to the unglycosylated ... triple mutant forms of HFE and incubated the cells in the presence and absence of tunicamycin Drug treatment resulted in the accumulation of an unglycosylated lower molecular mass form of the wild-type ... located at the end of an a-helical region of the HFE a1 domain (V100 and W103A) as being of particular importance for TfR1 interactions [16,17,20] The effect of HFE binding to TfR1 is to lower the affinity...

Ngày tải lên: 06/03/2014, 22:21

... within the Council in the foreseeable future Enhanced cooperation in the area of the establishment of a common system of FTT aims at ensuring the proper functioning of the internal market At the ... cooperation in the area of financial transaction tax THE COUNCIL OF THE EUROPEAN UNION, Having regard to the Treaty on the Functioning of the European Union, and in particular Article 329(1) thereof, Having ... 113 of the Treaty on the Functioning of the European Union (TFEU) the Council shall adopt provisions for the harmonisation of legislation concerning turnover taxes, excise duties and other forms...

Ngày tải lên: 06/03/2014, 19:20

... requirement of the two Similarly, both sets of regulations contain different requirement as to the format in which the information is provided The Provision of Services Regulations allow the information ... with the information already provided when she registered She then completes the rest of the form, saves it on her computer and then follows the instructions to upload it onto the site As there ... this type of information to a regulatory body in another EEA state, they must inform the relevant business of their actions and of exactly what information was provided provIdIngInformatIononyourbehalf...

Ngày tải lên: 06/03/2014, 21:20

... significantly changed either in the presence or absence of the metal cofactor By contrast, the substrate binding affinity of the RNase H domain probably increases in the presence of the metal cofactor compared ... that the conformation of the active site is not significantly changed on removal of the HBD Because the HBD is important for substrate binding, the HBD may affect the interaction between the enzyme ... HI, 10– 50 lm for Tma-CD, 1.0–10 lm for Tma-ND and 0.5–50 lm for Tma-W22A From the plot of the equilibrium binding responses as a function of the concentrations of the proteins, the KD value was...

Ngày tải lên: 06/03/2014, 22:21

... reductase catalyzes the formation of deoxyribonucleotides from the corresponding ribonucleotides, which is the rate-limiting step in the production of precursors for DNA synthesis [11] The mouse ribonucleotide ... from the R2 promoter in the presence of the R2 5¢-UTR In contrast, the R2-TATA box was required for full expression from R2-promoter templates lacking the 5¢-UTR However, the requirement of the ... indicated by the upper arrow to the left of the autoradiograph) and the adenovirus major late promoter ligated to a shorter G-less cassette (product indicated by the lower arrow to the left of the autoradiograph)...

Ngày tải lên: 08/03/2014, 02:20

... facing the severest threat to their existence ever as a result of the entry of the private sector in the provision of services formerly provided exclu- 10 sively by the posts and from the concomitant ... taxes, and for the receipt of pension, social insurance, and welfare benefits Postal savings for the people The introduction of savings accounts at post offices followed the rise of the savings ... Savings and the Provision of Financial Services widely seen as part of the agenda of Germany’s commercial banks to force the privatization and then take over the Landesbanks Even though the Sparkassen...

Ngày tải lên: 15/03/2014, 09:20

... capturing the impact of inflation and the effects of the fiscal-monetary policy mix; (iii) indicators for the openness of the economy and external competitiveness (such as the sum of export and ... (2007).14 We instrument the debt variable for each country through either its time lags (up to the 5th lag) or through the average of the debt levels of the other countries in the sample Both instruments ... Note: The variable gov_debt is instrumented for each country through either its time lags (up to the 5th lag; L(1/5).gov debt) or through the average of the debt levels of the other countries in the...

Ngày tải lên: 23/03/2014, 20:20

... to either the participants in these fisheries or the Nation are not available for a majority of the fisheries The use of the race for fish as a principal mechanism for allocating many of the groundfish ... value of $880 million in 2008, it accounted for 46% of the weight and 20% of the ex-vessel value of total U.S domestic landings as reported in Fisheries of the United States, 2008 The value of the ... were then applied to the rest of the fisheries The decline of other-king-crab bycatch in 2008 is explained in part by the reduction of effort in area 524 (no Pacific cod pot harvest occurred in area...

Ngày tải lên: 23/03/2014, 21:20

... number of samples Ó FEBS 2002 Role of the cytoplasmic C-terminus of SUR1 (Eur J Biochem 269) 5309 It shows the inhibition of channels in line A and E by ATP The deletion of the C-terminus of SUR1 ... progressive deletion of the C-terminus of SUR1 affects the efficacy of drug response To further characterize this, dose–response curves were constructed for two of these and it was found that the Ki was ... cell line of the effects of deletion of the SUR1 C-terminus on assembly, trafficking and function of the KATP channel complex The data reported here show that the cytoplasmic C-terminus of SUR1...

Ngày tải lên: 31/03/2014, 08:20

... α(n)1/n n→∞ n→∞ The proof of the second equality is very similar; it relies again on the formula T (G∗ ; x, y) = T (G; y, x), and the fact that the number of forests and the number of connected ... Proof By definition, the vector Xm encodes the contribution to the rank polynomial of the edges of the first column L1,m of Ln,m Every time we multiply by Λm we are adding the contribution of the ... all the edges ˆ ∼ (i, 1), for ≤ i ≤ n (see Figure 3) The reader may find it k helpful to think that for a fixed k, increasing n will make Fn grow to the right For the proofs of the following two theorems...

Ngày tải lên: 07/08/2014, 07:21

... for Biotechnology Information (NCBI) Genbank The alignment of the sequences and the construction of the phylogenetic tree were performed as described in [32] Gene structures of Arabidopsis and ... sufficient for chloroplast biogenesis and condition the formation of non-pigmented plastids Our working hypothesis is that the green sectors of var2 have compensating factors/activities that either ... stages On the other hand, most of the phenotypes of svr3-1 are intermediate between those of TAG-11 and wild-type, including size, extent of variegation and chlorophyll content (Figure 1A-B) The exception...

Ngày tải lên: 11/08/2014, 11:21

... BST-2 DNA to the limit of detection in 293T cells did not prevent the appearance of the faster migrating forms of BST-2 (data not shown) Thus, the appearance of faster migrating forms of BST-2 in ... high-mannose form of BST-2 Therefore, exogenously expressed BST-2 consists of two populations: a 30-40 kDa form containing complex sugar modifications (referred to as "postER form" for the remainder of the ... dimerization The fact that none of these mutations affected BST-2 function supports the notion that the loss of activity seen for the triple cysteine mutant is due to the lack of protein dimerization rather...

Ngày tải lên: 12/08/2014, 23:22

Ngày tải lên: 27/03/2015, 13:46

... CONTROL OF THE CENTRAL AREA IN LARGE CITIES 2.1 Methodology The thesis has used several methods, such as the expert method, the information processing method, the materials, the survey method, the forecasting ... towards the West and the Northwest The central business district was proposed to adjust the scale by 2006, increased total area of 930ha Under impacts of the market economy and the Doi Moi Reform of ... intension of the training should be focus on main points: The recruited officers for the inspection force should be professional specialists Allocate the human resources as their professional...

Ngày tải lên: 20/06/2015, 09:02

... on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the VA population Moreover, we might expect that the PPV and NPV of the ... NC) Results The characteristics of the VARA participants measured at the start of each treatment episode were evaluated Because the characteristics of VARA patients at the start of non-biologic ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic...

Ngày tải lên: 25/10/2012, 10:45

... end -of- life issues to patients and their families [11] It is not uncommon for physicians to ask loaded questions in their quest for end -of- life decisions For example, ‘This is your grandmother’s ... revitalize the patient population of ICU patients who will die no matter what treatment is rendered them Medically inappropriate care causes pain, suffering, and discomfort The fundamental maxim for these ... 10 11 12 13 14 Perhaps the most effective way of dealing with strong familial incentives to tread the path of least resistance in end -of- life care is twofold First, in end -of- life issue discussions,...

Ngày tải lên: 25/10/2012, 10:45

... dimethyl-1,2,4,5-tetrazine-3,6-dicarboxylate The first highly active part of the construct, allows the ligation of e.g carrier molecules on the desired side of the molecule The second dienophile on the other side with lower ... of the dansyl derivative and the N-ethyl-diisoproylamine and the dansyl sulfamidoethylamine to the tetrazine product linked with 5-dansyl sulfamidoethylcarboxamide-2-yl For the syntheses of the ... 1665.9) for chemical reaction by the solid phase peptide synthesis (Figure 4) Ligation of the pentamer I with the tetrazine-dicarboxylate 6: One µmol of the pentamer I (Figure 3) and 5.5 µmol of the...

Ngày tải lên: 25/10/2012, 11:00

... attempted for three SPT patients in whom the mass was located in the portion of body or tail of the pancreas For tumors of SPT located in the neck and body of the pancreas, resection of the midportion ... midportion of the pancreas and the mass with preserving the rim of the head and tail portion can be achieved However, for the patient in whom the mass was located within the head of the pancreas, ... 311 Fig The CT scan indicated the typical internal or capsular calcification in the SPT Once the diagnosis of SPT is made, surgery is the first choice of treatment, since other adjuvant therapies,...

Ngày tải lên: 25/10/2012, 11:40

... 100% relief of their pain in 86% of the patients with a median relief period of months The range of relief varied from zero days to up to 13 months for the facet injection group None of the lumbar ... median period of pain relief being months The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure Of the 14 patients ... that the direct visualization of the joint allows better de-innervation of the joint and removal of the entire end-plate receptors that adhere to the bone and capsular tissue Limitations of the...

Ngày tải lên: 26/10/2012, 09:32