and ptx loaded polymeric micelles
Development of multi functionalized polymeric carriers for delivery of anticancer drug combinations
... DOX and free PTX combinations 80 Figure 4.4 In vitro release profiles of (A) DOX from DOX- micelles, DOX- FOL micelles and DOX- TAT/FOL micelles; and (B) PTX from PTX- micelles, PTX- FOL micelles ... and co-delivery of TAM- TAT/FOL micelles & PTX- TAT/FOL micelles_ 0.6/1; (B) PTX micelles, PTX- TAT/FOL micelles and co-delivery of TAM- TAT/FOL micelles & PTX- TAT/FOL micelles_ 0.6/1 The synergistic ... of TAM and PTX from (A) TAM-TAT/FOL micelles and PTX- TAT/FOL micelles, and (B) TAM /PTX( 0/6/1)-TAT/FOL micelles in PBS (pH 7.4) at 37ºC The experiments were conducted in triplicate The standard...
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Advantages and challenges of the spray drying technology for the production of pure drug particles and drug loaded polymeric carriers
... outstanding advantages and challenges of the spray-drying method for the production of pure drug particles and drug -loaded polymeric particles and discusses the potential of this technique and ... MANUSCRIPT Advantages and challenges of the spray-drying technology for the PT production of pure drug particles and drug -loaded polymeric carriers SC RI Alejandro Sosnik1* and Katia P Seremeta2,3,4 ... drugs, SC extracts, aromatic oils, pigments, and flavors within different types of carriers such as NU polymeric nanoparticles (NPs) and microparticles (MPs) and nanocomposite MPs [42,43,52] In addition,...
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analysis and deformulation of polymeric materials paints, plastics, adhesives, and inks
... methods and instruments; followed by formulations, materials, and analysis of paint, plastics, adhesives, and inks; and finally reformulation methods to test the results of analysis Materials and ... tools, and materials such as polymers and pigments require corresponding instrumentation for identification and characterization such as infrared spectroscopy and X-ray diffraction The methods and ... information please contact the publisher Analysis and Deformulation of Polymeric Materials Paints, Plastics, Adhesives, and Inks Jan W Gooch Polymers and Coatings Consultant Atlanta Georgia KLUWER...
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design, synthesis, and characterization of polymeric materials for uses in energy storage applications
... publication in Macromolecules and was coauthored by H.R Allcock and D.A Stone Chapter has been adapted for publication in Chemistry of Materials and was coauthored by H.R Allcock and D.A Stone Chapter ... State Ionics and was coauthored by H.R Allcock and Y Chang Chapter has been adapted for publication in Solid State Ionics and was coauthored by H.R Allcock, R.M Morford, C.E Kellam III, and M.A Hoffmann ... opportunity to join his research program and for his constant support and guidance throughout my graduate studies The chemical knowledge, verbal and written presentation, and experimental skills which I...
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A mechanism based approach void growth and coalescence in polymeric adhesive joints
... understand how variations in temperature and moisture degrade mechanical properties of polymeric materials and adhesives and activate damage mechanisms which in turn lead to adhesive cracking and ... to conditions of relatively high stress and temperature (Evans and Hutchinson, 1995; Strohband and Dauskardt, 2003) An important example is the failure of polymeric die-attach layers during the ... research fellow and mentor, for his invaluable guidance and insightful knowledge in continuum mechanics His passion and enthusiasm for research work was contagious and had been, and most surely...
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Multifunctional folate conjugated polymeric micelles for active intracellular drug delivery
... Micelles size and size distribution of (a) TPGS micelles and (b) mixed micelles with 10% TPGS 112 Figure 6.2 Drug release profiles of DOX -loaded PLGA-PEG-FOL micelles and mixed micelles ... PLGA-PEG micelles, (c) DOX -loaded PLGA-PEG-FOL micelles, (d) DOX -loaded mixed micelles with 5% TPGS, (e) DOX -loaded mixed micelles with 10% TPGS and (f) Fibroblasts treated with mixed micelles ... micelles and (b) PLGA-PEG-FOL micelles 56 Figure 3.10 AFM images of (a) PLGA-PEG micelles and (b) PLGA-PEG-FOL micelles 56 IX Figure 3.11 Size and size distribution of DOX-loaded...
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Controlled release of anticancer drugs, proteins and liposomes by polymeric microspheres
... materials and paclitaxel -loaded microspheres Figure 3.5 Surface and internal morphology of paclitaxel -loaded microspheres Figure 3.6 DSC thermograms Figure 3.7 In vitro release of paclitaxel from polymeric ... also form micelles in aqueous environment with PEG on the surface Compared to surfactant micelles, these polymeric micelles are more stable, have a lowered critical micellar concentration, and have ... more hydrophilic molecular structure and more amorphous state of the polymer, and smaller particle size and higher porosity of the polymeric microspheres [Edlund and Albertsson, 2002] By assuming...
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Design of functional polymeric micelles as a carrier for anticancer drug delivery
... (A) blank and (B) DOX -loaded PEG5K-PAC, PEG5K-PUC and PEG5K-PAC/PEG5K-PUC mixed micelles, and (C) blank as well as (D) DOX -loaded PEG10K-PAC, PEG10K-PUC and PEG10K-PAC/PEG10K-PUC mixed micelles ... location and content on particle size and DOX loading (A) Particle size and DOX loading of micelles formed from PEG-PECPAC2 (end), PEG-PAC-PEC (middle) and PEG-PEAC (random); (B) Particle size and ... from DOX -loaded 1b micelles 81 4.3.5 Cellular uptake of DOX 82 4.3.6 Cytotoxicity studies of blank and DOX -loaded 1b micelles 83 4.3.7 Biodistribution of DOX -loaded 1b micelles...
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Báo cáo y học: "Pravastatin Provides Antioxidant Activity and Protection of Erythrocytes Loaded Primaqe"
... fragility and oxidative damage of erythrocytes of zinc-deficient rats J Nutr 1997; 127: 1290–1296 Lajos N, Miki N, Sandor S Protein and non-protein sulfhydryls and disulfides in gastric mucosa and ... TCA and resuspended in 1.0 ml of M HCl for blank and M HCl containing 2% 2,4dinitrophenyl hydrazine After incubation for h at 37°C, protein samples were washed with alcohol and ethyl acetate, and ... gluteraldehyde Aldehyde was drained and rinsed times each of in phosphate buffer and post-fixed in osmium tetroxide for h After this, the samples were rinsed in distilled water and then dehydrated using...
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Báo cáo khóa học: Conformational changes of b-lactoglobulin in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles A fluorescence and CD study docx
... appropriate fluorescence standards together with the standard provided with the instrument The quantum yields of NATA and bLG were determined relative to that of Trp alone, at pH 7.0 and in aerated aqueous ... for absorption at the excitation wavelength) and Fo and Fw are, respectively, the fluorescence intensities in the absence and Ó FEBS 2004 736 S M Andrade et al (Eur J Biochem 271) presence of ... (AOT) RM and in pure water Far-UV CD spectra in: 1, water; 2, AOT, x0 ¼ 3; 3, AOT, x0 ¼ 5; 4, AOT, x0 ¼ 15; 5, AOT, x0 ¼ 30; and 6, GdnHCl (6 M) (B) CD spectra of bLG in AOT (1–4) and SDS (5 and 6)...
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Báo cáo Y học: Binding of Thermomyces (Humicola) lanuginosa lipase to the mixed micelles of cis-parinaric acid/NaTDC Fluorescence resonance energy transfer and crystallographic study ppt
... donor (TLL tryptophans) and an acceptor (fatty acid) is that there must exist a spectral overlap between the donor emission and the acceptor absorption spectra, and the donor and acceptor groups ... concentration Data from Fig Fig FRET between TLL (and its mutants) and cis-PnA in the presence and absence of NaTDC The protein concentration was 0.8 lM and the cis-PnA concentration was varied stepwise ... stereoview of OA binding modes in molecule A and B (OA_A and OA_B, respectively, thick lines); C9 and C10 correspond to the position of these atoms in the OA_A ligand, where the electron density was visible...
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inorganic polymeric nanocomposites and membranes (advances in polymer science) (advances in polymer science)
... properties and of the glass transition temperatures of the (A)n and (B)n homopolymers and of the (AB)n random and alternated copolymers and (BAB)n alternated copolymers has been achieved and showed ... led to an increased viscosity and difficulty in handling and degassing materials, producing remnant voids Nonetheless, Jang and other groups such as that of Sohn and Hu [28] showed that the use ... and 29 Si NMR spectroscopy The GPC analysis showed that high molecular weights were obtained (20 000–40 000) and the DSC and TGA analyses showed very low Tg s, in the range – 77 to – 80 ◦ C and...
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buchmeiser - polymeric materials in organic synthesis and catalysis (wiley, 2003)
... aspects and the practical applications of such modern polymeric supports in organic syntheses and the emerging new opportunities of nanoreactor design by means of micellar catalysis and novel ... XXI Structure, Morphology, Physical Formats and Characterization of Polymer Supports Yolanda de Miguel, Thomas Rohr and David C Sherrington Synthesis and Molecular Structure of Polymer Supports ... Area and Pore Sizes 20 Network and Pore Connectivity Effects 23 Hg Intrusion Porosimetry Involving Dry Supports 24 Theory 24 Comparison between Nitrogen Sorption and Mercury Intrusion 27 Polymeric...
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Báo cáo hóa học: "Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol" potx
... evaporation method, and propofol -loaded plain and mixed micelles were prepared by simply mixing drug-free plain and mixed micelles and propofol, respectively Owing to the fact that size and size distribution ... housed with free access standard food and tap water, and exposed to alternating 12 h periods of light and darkness Temperature and relative humidity were maintained at 25°C and 50%, respectively ... plain micelles and mixed micelles were PLA chains, and PLA and octadecyl chains, respectively The hydrophobic interaction between PLA segments was greater than that between PLA segment and octadecyl...
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Báo cáo hóa học: " Characterisation and Skin Distribution of Lecithin-Based Coenzyme Q10-Loaded Lipid Nanocapsules" ppt
... (CoQ10 and GTCC), and the amount of lipid (CoQ10 and GTCC) was kept at a fixed concentration of 12.5% (w/w) with regard to the total mass of 100 g Briefly, CoQ10 and GTCC were mixed at 60°C, and then ... the dermis layer and the epidermis layer, surfactant-free CoQ10 -loaded lipid nanocapsules (CoQ10-LNCs), composed of the lamellar shell of lecithin and an inner lipid core of CoQ10 and GTCC, were ... 10,000–50,000 and at a defocus of 3–5.46 lm 1563 by Image-pro plus software (Media Cybernetics, USA) The excitation and emission wavelengths were 549 and 628 nm for NR We selected green light and red...
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Báo cáo hóa học: " Facile Preparation of Crosslinked Polymeric Nanocapsules via Combination of Surface-Initiated Atom Transfer Radical Polymerization and Ultraviolet Irradiated " docx
... in Fig 3a and b The collapse of the crosslinked polymeric shells during the etching in DMF maybe due to the lower crosslinking degree [29] and the osmotic pressure between the inner and outer ... tetrahydrofuran (THF), ethanol, hydrofluoric acid, and other solvents used were all of analytical reagent grade and obtained from Tianjin Chemical Co., Tianjin, China, and were used without further purification ... collected by centrifugation, washed thoroughly with THF, and dried under vacuum Analysis and Characterization Elemental analysis (EA) of C, N, and H was performed on Elementar vario EL instrument...
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Báo cáo hóa học: " Studies on Preparation of Photosensitizer Loaded Magnetic Silica Nanoparticles and Their Anti-Tumor Effects for Targeting Photodynamic Therap" ppt
... mother liquor and (b) PHPP-SMNPs Fig UV spectra of (a) PHPP, (b) PHPP mixed with SMNPs, (c) PHPP dissolved in HCl and ethanol, (d) SMNPs dissolved in HCl and ethanol, and (e) SMNPs and PHPP dissolved ... (d) indicated absorptions of SMNPs and HCl at 240, 314, and 364 nm, demonstrating that the 240, 314, and 364 nm peak of the spectrum (e) attributed to SMNPs and HCl Therefore, the 409 nm was the ... absorption of PHPP and SMNPs mixture was caused by the Fig 10 UV spectra of the PHPP-SMNPs treated with HCl and ethanol 123 406 Fig 11 The standard curve of PHPP dissolved in HCl and ethanol, measured...
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Báo cáo hóa học: " Fabrication of Highly Ordered Polymeric Nanodot and Nanowire Arrays Templated by Supramolecular Assembly " pot
... chloroform, methanol, and dichloromethanes were purchased from Acros Organics and used as supplied Fabrication of Ordered Nanodots and Nanowire Arrays PS-PVP and HABA (1 mol of HABA and mol of 4vinylpyridine ... action and hydrogen bonding, this ordered nanoporous template can be perfectly transferred, and thus achieved a methodology for the preparation of highly ordered sub-30 nm polymeric nanodot and ... h and keep h), to remove the PS-PVP and resulted ordered nanodots arrays (Fig 1) Nanoscale Res Lett (2009) 4:459–464 461 Fig Scheme of the fabrication of highly ordered polymeric nanodot and...
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Báo cáo lâm nghiệp: "Strength properties of thermally modified softwoods and its relation to polymeric structural wood constituents" pot
... developed and industrially applied, such as the Torrefaction and Rectification process in France [10, 50], the Thermowood process in Finland [49] and the Plato process in the Netherlands [7] This ... strength (parallel and perpendicular to the grain; respectively DIN 52185 and DIN 52192), and tensile strength (parallel to the grain; DIN 52188), and Brinell hardness (parallel and perpendicular ... model by Rowell and Winandy [55] They suggest that mechanical properties, which relates to internal stress and strain, are simply functions of chemical bond strength: covalent and hydrogen intrapolymer...
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Báo cáo khoa hoc:" Evaluation of triblock copolymeric micelles of δvalerolactone and poly (ethylene glycol) as a competent vector for doxorubicin delivery against cancer" doc
... using FT-IR and 1H NMR In the FT-IR spectra of the copolymer, the characteristic bands at 2875 cm-1 and 1100 cm-1 represent the C-H stretching and C-O-C band of PEG, respectively The band at 1726 ... delivery Preparation and properties of DOX loaded copolymeric micelles (VEVDMs) Avoiding the time consuming and low encapsulation efficiency yielding methods like dialysis and nanoprecipitation ... and 19.5% MCF7 and U87MG cells underwent apoptosis, whereas only 34.9 and 9.1%, MCF7 and U87MG cells were apoptotic after treatment with equivalent concentration of free DOX Also, empty VEV micelles...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25