... Chapter 056. Cutaneous Drug Reactions (Part 1) Harrison's Internal Medicine > Chapter 56. Cutaneous Drug Reactions CUTANEOUS DRUG REACTIONS: INTRODUCTION Cutaneous reactions are ... adverse cutaneous reactions. INCIDENCE OF CUTANEOUS REACTIONS Several large cohort studies established that acute cutaneous reaction to drugs affected about 3% of hospital inpatients. Reactions usually ... frequent adverse reactions to drugs. Every physician will see patients suffering from them. Most are benign, but a few can be life-threatening. Prompt recognition of severe reactions, drug withdrawal,...
Ngày tải lên: 07/07/2014, 01:20
... Cutaneous Drug Reactions (Part 2) PATHOGENESIS OF DRUG REACTIONS Untoward cutaneous responses to drugs can arise as a result of immunologic or nonimmunologic mechanisms. A variety of adverse ... most often affected by adverse drug reactions. The list of conditions that can be triggered by medications includes nearly all dermatologic diseases. Many of these adverse reactions result from ... preventive measures. Immunologic Drug Reactions For most acute drug eruptions, benign or severe, accumulated data suggest an immunologic basis. In the last 10 years drug- specific T cell clones were...
Ngày tải lên: 07/07/2014, 01:20
Chapter 056. Cutaneous Drug Reactions (Part 3) docx
... PRESENTATION OF CUTANEOUS DRUG REACTIONS Nonimmune Cutaneous Reactions EXACERBATION OR INDUCTION OF DERMATOLOGIC DISEASES stimulation of T cells by medications leads to reactions that are ... neutrophil-mediated drug reaction. One may therefore assume that the final pattern of drug eruptions results both from the nature of effectors—cytotoxic T cells in blistering reactions, chemokines in reactions ... and response. GENETIC FACTORS AND CUTANEOUS DRUG REACTIONS Specific genetically determined defects in the ability of an individual to detoxify toxic reactive drug metabolites predispose such...
Ngày tải lên: 07/07/2014, 01:20
R INTE S OF MEDIC REPORTING ADVERSE DRUG REACTIONS DEFINITIONS OF TERMS AND CRITERIA FOR THEIR USE ppt
... of skin lesions and therefore encompassing virtually all cutaneous adverse reactions. As a general rule, in reporting cutaneous drug reactions specific terms should be used, but only when the ... for Reporting Adverse Drug Reactions 9 Skin and Appendages Disorders (SOC 0100) 9 Introduction 9 Terms 10 Dermatitis (Eczema) 10 Dermatitis exfoliative 10 Fixed drug eruption. 11 Lichenoid drug eruption ... effects, side-effects or adverse reactions. A product which the drug regulatory agency authorizes for marketing still requires intensive post- marketing monitoring. Many adverse reactions can be detected...
Ngày tải lên: 07/03/2014, 10:20
Women and Adverse Drug Reactions Reporting in the Canadian Context pot
... Servi D, et al. Incidence of adverse drug events and potential adverse drug events. JAMA1995;274:29-34. 48 Rosenbloom, David, Wynne, Christine Dectecting adverse drug reactions CMAJ, August 10, ... adverse drug reactions in Canada, using a 1:10 ratio of the population of Canada to that of the US, would total 7,600 annually – 10% of the estimated 76,000 deaths due to adverse drug reactions ... voluntary reporting of adverse drug reactions was inadequate, the jury’s key recommendation called for a national system for the mandatory reporting of adverse drug reactions. Mandatory reporting,...
Ngày tải lên: 22/03/2014, 11:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) pdf
... 1báo cáo về bệnh thận nhiễm độc. (theo Reactions Weekly; Số 1018; 11/9/2004) TCNCYH 36 (3) - 2005 91 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) G.S. Hoàng Tích Huyền Bộ...
Ngày tải lên: 25/03/2014, 05:20
Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) docx
... TCNCYH 29 (3) - 2004 Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) GS.TSKH. Hoàng Tích Huyền* 1. Gatifloxacin và chuyển hoá bất thờng ... cảm, lú lẫn, thao thức khi đó phải ngừng ngay mefloquin và báo cáo với thầy thuốc". (Theo Reactions Weekly, 01/11/2003, số 975). 4. Doxycyclin gây viêm loét thực quản (Australia, Tân Tây...
Ngày tải lên: 03/04/2014, 00:20
Báo cáo y học: " Parkinsonism caused by adverse drug reactions: a case series." pps
Ngày tải lên: 11/08/2014, 00:23
Báo cáo y học: "Potential Adverse and Allergic Reactions from Complementary and Alternative Medicine and Dietary Supplements" pptx
Ngày tải lên: 08/08/2014, 21:20
Tài liệu Color Atlas of Pharmacology (Part 8): Adverse Drug Effects pptx
... reserved. Usage subject to terms and conditions of license. Adverse Drug Effects 71 A. Adverse drug effect: overdosing B. Adverse drug effect: increased sensitivity Effect Dose Decrease in pain ... in mother Unwanted effect in child Drug ? Extent of transfer of drug into milk Infant dose Rate of elimination of drug from infant Distribution of drug in infant Drug concentration in infant´s blood Effect Ovum 1 ... a prerequisite. 70 Adverse Drug Effects Lüllmann, Color Atlas of Pharmacology © 2000 Thieme All rights reserved. Usage subject to terms and conditions of license. Adverse Drug Effects 75 Development stage Nidation...
Ngày tải lên: 26/01/2014, 19:20
Veterinary Pharmacovigilance Adverse Reactions to Veterinary Medicinal Products docx
... medicinal products and potential adverse effects 355 P. Silley 17 Adverse effects of veterinary pharmaceutical products in animals 393 K.N. Woodward 18 Adverse drug reactions in dogs – toxic hepatic ... hepatic responses 423 K.N. Woodward 19 Adverse reactions to vaccines 453 K.N. Woodward and L.A. Toon 20 Adverse reactions in humans following exposure to veterinary drugs 475 K.N. Woodward 21 Medicines ... Jönsson, B. (2004) Pharmacoeco- nomics of adverse drug reactions. Fundamental and Clinical Pharmacology, 18, 275–280. Mann, R.D. (1993) Regulation of drugs in Europe and the United Kingdom....
Ngày tải lên: 06/03/2014, 16:20
báo cáo hóa học: " A review of methods used in assessing nonserious adverse drug events in observational studies among type 2 diabetes mellitus patients" docx
... reports of adverse drug reactions reflect patients ’ concerns? Pharm World Sci 2004, 26:155-159. 65. Van Grootheest K, de Jong-van den Berg LT: Patients’ role in reporting adverse drug reactions. ... Nielsen LH, Hansen EH: Consumer reporting of adverse drug reactions: a retrospective analysis of the Danish adverse drug reaction database from 2004 to 2006. Drug Saf 2009, 32:1067-1074. 70. Jarernsiripornkul ... direct source of information on adverse drug reactions. BMJ 1988, 297:891-893. 68. Ferrari A, Spaccapelo L, Gallesi D, Sternieri E: Focus on headache as an adverse reaction to drugs. J Headache Pain 2009,...
Ngày tải lên: 20/06/2014, 15:20