... experiments, analyzing data and writing the manuscript TBK participated in initiating the idea cartilage and proof read the manuscript MHZ participated in design the experimental method and acknowledge of ... image using Alcian Blue staining was obtained to grade the physiological status of AC in terms of International Cartilage Research Society (ICRS) scores and understand the approximate concentration ... roughness ofthe AC surface shows the interwoven collagen network near the articular surface may play an important role in prevention ofthe initial lesion of AC surface and increase ofthe durability...
... mismatch in PNAÆDNA and DNA duplexes T Rathinavelan and N Yathindra Fig Interaction of water (orange) with A2 4 .C7 mismatch in PDwt (A L) and DDwt (M–T) during the dynamics Variation in hydration ... PNAÆDNA and DNA duplexes Intra strand base stacking at the AC(6–7) (Fig 2A) & CC(7–8) steps (Fig 2B) ofthe DNA strand, and GA(23–24) (Fig 2C) and AT(24–25) (Fig 2D) steps ofthe PNA strand, flanking ... different atoms of PNA chain Fig S3 Partial charges for the bases in: (A D) PNA and as given in Parm99.dat forcefield for a DNA chain (E–H) The following supplementary material is available online:...
... synthesis ofthe negative strand of DNA can result inthe insertion ofa uracil as a result ofthe deamination ofa cytosine, leading to the inclusion of an adenosine instead of guanosine in ... hypermutation may involve a cellular factor, APOBEC3G, a cytidine deaminase that converts cytosine to uracil The activity of APOBEC3G is inhibited by the Vif protein.[5,7,8] Inthe absence of Vif, the ... positive-stranded cDNA This results in mutant viruses that contain several G A changes With cell passage, more G A mutations in viral DNA occur and infectivity is diminished Furthermore, trace amounts of...
... relevant to the teaching and research needs and activities ofthe CARD project participants The emphasis on 'training the trainers' and networking was an efficient and sustainable way to establish ... expanded range and quality of material being taught In addition, the research capacity ofa group of staff within the Ministry of Agriculture and Rural Development has been significantly increased ... capacity building with particular emphasis on ‘training the trainers’ Over the period ofthe project there has been a significant shift inthe material used in teaching programs andinthe approaches...
... 1)! Again, the maximality of I implies that m = n and so I has the required shape as above Proof of Theorem 1.4 As before, the upper bound of |I| is given by the existence of Latin squares of ... half of these permutations are odd Now, interchange the entries containing the symbols n − and n in these odd permutations Together with the remaining even ones, they form a desired Latin square ... Furthermore, if equality holds in (1), then for any independent set I of cardinality α(Γ ) in Γ2 , φ−1 (I) is an independent set of cardinality α(Γ1 ) in Γ1 Intersecting families inthe alternating...
... involved inthe analysis of results and writing the manuscript All the authors read and approved the final version Acknowledgements The authors are very grateful to Edita Lukić, Goran Madžarac and Alen ... according to the ACC/AHA criteria [26,27] Statistical analyses MedCalc™ v 9.6.2.0 (MedCalc Software, Mariakerke, Belgium) statistical software was used for all statistical analyses Categorical data ... participated in patients' inclusion and follow-up, performed statistical analyses, analyzed results and wrote the manuscript AVB and VG participated in patients' inclusion and follow-up IPR was involved...
... unclear pronunciation, their bad voice quality, lack of confidence all made it difficult for them to be understood Besides, the data from the study confirm the fact that the infrequent and inadequate ... On the part ofthe second-year majors, for example, in order to be effective learners of English in general and effective speakers in particular, they need to improve their knowledge ofthe target ... University The survey questionnaire completed by the students was the main instrument employed for the collection of data The research reveals that the students’ low language proficiency including unclear...
... presentation, (2) rewriting it for the ear, (3) practising and revising it, and (4) organizing the visual aids Once the learner has made an outline ofthe main points, write the presentation The main ... relevance and importance ofthe study, as well as to clarify any questions that the learners had 2.3 Data Analysis and Discussion ofthe Findings 2.3.1 Data Analysis 20 In order to interprete the ... of speaking, types of classroom speaking, and some aspects of oral presentations These issues are the focus ofthe chapter 1.1 Introductory Remarks In language teaching, a great importance has...
... Asia (India, Pakistan and Bangladesh), Africa andthe Caribbean At the time ofthe 2001 Census, Indians were the largest minority group, followed by Pakistanis, Black Caribbeans, Black Africans ... from the Caribbean, Pakistan and Bangladesh have lower education and occupational qualifications than whites, on average, those from India, Africa and China have higher average qualifications ... and years (age data are not yet available) These interviews andthe baseline survey provide detailed information on the demographic, social and economic situations ofthe families andthe health...
... higher in fractions and than in fraction (Table 1) These results indicate that fraction contains a significant number of mitochondria, and that fraction is the main lysosomal fraction The DNAcleavage ... cells and incubated with a circular plasmid as the substrate DNA The substrate plasmid DNA was 5381 Mitochondria in nuclear death of Tetrahymena T Kobayashi and H Endoh B A C Fig Mitochondrial nuclease ... by Lu and Wolfe [23], who used a combination strategy of 4,6-diamino-2-phenylindole (DAPI) staining for the detection of DNA and Azo dye staining for the identification of acid phosphatase activity,...
... between A- and B-chains In WT thrombin, the A- chain assumes an overall boomerang-like shape interacting with the B-chain surface opposite to the active site [17] Stabilization within the A- chain and ... intra- and interchain bonds After 180 denaturation with m urea and 0.2 mm b-mercaptoethanol, the A- chain was released andthethe native enzyme form disappeared for both WT and mutant thrombin ... steady-state amidase activity and binding ofthe high-affinity inhibitor a- NAPAP showed pKa values ofthe catalytic His57 higher in DK9 mutant than in WT thrombin Application ofthe Brønsted theory...
... substrates The data for the PA catalysed hydrolysis of PhAc-Asp and PhAc-Glu [13] and our data for PhAc-pAB, PhAc-mAB and PhAcoAB (Table 2) imply that the COOH group has to be positioned as in NIPAB ... polar CO2– and O(NO) and positively charged guanidinium fragments of ArgA145 and ArgB263 ˚ Table Distances (A) between polar substrates groups (CO2– andA NO2) andthe two ArgB263 and ArgA145 ... O atoms ofthe main chain CO groups of LeuB387 and TrpB240, Od1 atom of AsnB241, and Oc atom of SerB386 and is expected to stabilize the positive charge of ArgB263 All of these views remain arguable,...
... forward 5¢-ATGGCACCAAAAGCAAAAATCG-3¢ and reverse 5¢-AGCTAATGCCTTCATTCTCTTAG-3¢; Pf MQO forward 5¢-ATGATATGTGTTAAAAATATTTTG-3¢ and reverse 5¢-TCATAAATAATTAACGGGATATTCG-3¢) Both PCR and RT-PCR products ... catalysed the reduction of OAA with an efficiency six to eight times greater than that of oxidation of malate as determined by evaluation of Vmax and kcat values for malate/NAD and OAA/NADH (Table ... (2002) Preparation of pure and intact Plasmodium falciparum plasma membrane vesicles and partial characterization ofthe plasma membrane ATPase Malar J 1, 1–7 28 Bradford, M.M (1976) A rapid and sensitive...
... far as the side ofthe boat The Old Man AndThe Sea portrays Hemingway Code Heros to their fullest potential As Heros they try their hardest to persevere under pressure and achieve the goal in ... front of them They show the characteristics ofa stoic, working hard inthe hardest of situations Hemingway Code Heros are very rare in real life, but in fiction they survive, setting good examples ... offered each other the best of company While out at sea Santiago is constantlywishing the boy was there to talk to or to help with the mighty fish Santiago does not have relationships with any...
... computational time and at the moment is not suitable for a practical application. On the other hand, based on results of Nadaoka et al [9], Ting and Kirby [15‐17], it can be estimated ... significantly dissipated when a new wave arrives and breaks. Thus, the time variation of TKE is relatively small, andthe combination of wave‐induced flow and undertow may transport TKE and suspended ... wave breaking on a natural beach To verify the accuracy ofthe numerical model on the simulation ofthe wave transformation on a natural beach, existing experimental data on the wave dynamics in ...
... throughout the discussion of starting a postal savings bank Advocates invariably cited the predicament of rural citizens who lived many miles from a bank, andthe lack of savings facilities available in ... change The United States and Canada abolished their postal savings systems over thirty years ago, New Zealand anda number of European countries have privatized theirs starting inthe 1980s and ... savings bank law in 1893 Then, when protests led to relaxation ofthe supervisory standards in 1895, the savings banks took off again, far surpassing the growth ofthe postal savings system and of...
... andthe area dorsal to the substantia nigra inthe midbrain reticular formation By immunostaining using monoclonal antibody against the N-terminus ofthe human relaxin-3 A- chain [2], relaxin-3-immunoreactive ... relaxin ⁄ INSL7 inthe nucleus incertus of rat brain Regul Pept 145, 54–59 24 Osheroff PL & Ho WH (1993) Expression of relaxin mRNA and relaxin receptors in postnatal and adult rat brains and hearts ... hippocampus, hypothalamus, mammillary complex and amygdala, are involved in arousal mechanisms, including the synchronization and desynchronization ofthe theta rhythm [14,15] Recently, Ma et al...
... can be positive or negative, and values greater than unity are rare [37] and indicative of protein–protein interaction and ⁄ or downstream mechanisms that act synergistically Glucokinase has a ... expression or inactivation Linear plots of glycogen synthesis against phosphorylase -a (A) and active glycogen synthase against phosphorylase -a (B) for the data in Figs 2–4 for hepatocytes from Fa ⁄ ? ... by the finding that in hepatocytes, unlike in muscle, inactivation of phosphorylase rather than inactivation of glycogen synthase kinase-3 is a major component ofthe mechanism by which insulin...
... domain B) from AMY2 (in green) and TAA (in black) The superimpositioning was guided by the catalytic acids (D179AMY2, E204AMY2, and D289AMY2 and D206TAA, E230TAA, and D297TAA) The invariant Y51AMY2 ... onto the valienamine ring in AMY2/acarbose (Fig 1A) Superpositioning of AMY2 and TAA guided by the catalytic acids was excellent for Tyr51AMY2 and Tyr82TAA (Fig 1A) and mutation in Saccharomycopsis ... complexes of inhibitory substrate analogues derived from acarbose and barley a- amylase (AMY2 [16]); and Taka-amylase A (TAA [17]) (A) Stereo view of interactions involving segments of ba loops and...
... and you’re ready to install the app INSTALLING AND UNINSTALLING APPS AND PROFILES You have your provisioning profile and your app Now, it’s time to install When using the iPCU, installing an app ... disable Safari?) However, if you want to maintain control of what apps are installed or deleted, you can that here You can also prevent changes in email accounts, disable camera usage, manage in- app ... software and hardware products described in it Trademarks iOS, iPhone, iPad, and iTunes are trademarks of Apple, Inc., registered inthe United States and other countries Many ofthe designations...