... degradation of acetylene by anaerobic bacteria proceeds by the same pathway (Schink 1985b) 6.2 Aerobic Degradation of Aromatic Hydrocarbons and Related Compounds The degradation of aromatic compounds ... converging lines of investigations have examined in detail (1) the degradation of the monocyclic aromatic hydrocarbons benzene and toluene and (2) the degradation of oxygen-substituted compounds such ... the degradation of polycyclic aromatic hydrocarbons (PAH) Since many of these metabolic sequences recur in the degradation of a wide range of aromatic compounds, a brief sketch of the principal...
Ngày tải lên: 11/08/2014, 04:20
... scholarship and the financial support -i- PhD Thesis Jiang Zhaoqin Table of Contents Acknowledgements i Table of Contents ii Summary ix List of Tables xi List of Schemes xiii List of Figures xv List of ... Department of Chemistry, NTU, for their assistance in the biological tests of our synthetic compounds I also wish to thank Prof Wong Ming Wah and his group members from Department of Chemistry, ... 1, 2, and are concerned with the first topic, and chapter is related to the second topic Chapter provides a brief historic overview of the development of asymmetric organic catalysts, and some...
Ngày tải lên: 14/09/2015, 08:39
Báo cáo khoa học: Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E2 receptor EP2 through cAMP elevation and protein kinase A pot
... action of PGE2 and ligands of receptor A2B and b2-AR (NECA and ISO) might result from different effects of those compounds on PAR-1 mRNA stability However, PGE2 did not influence the rate of PAR-1 ... or the rate of internalization and degradation of PAR-1 protein As we and others [15–17,26,33] have shown the role of cAMP in the suppression of fibroblast function and promotion of the antifibrotic ... downregulation of mRNA and protein levels of PAR-1 On the other hand, inhibition of PKA by its inhibitor H-89 prevented PAR-1 downregulation Similarly, the involvement of the PKA pathway and the lack of...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Induction of PAI-1 expression by tumor necrosis factor a in endothelial cells is mediated by its responsive element located in the 4G/5G site ppt
... 2.5, 2.0; 1.5, 1.0; 0.5 and 0.25 lL of synthesized cDNA were amplified in triplicate for both b-actin and each of the target genes to create a standard curve Likewise, lL of cDNA was amplified in ... the concentration range 0–1000 nm to prevent degradation of IjBa In the presence of MG132, TNFa-induced expression of PAI-1 detected at the level of mRNA (Fig 5C) or protein synthesis (Fig 5A) ... and p65 This binding is specific and can be abolished by triple mutation of the oligonucleotide, as seen both in the direct binding and during competitive inhibition experiments (b) Mutation of...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo sinh học: "The combined transduction of copper, zincsuperoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury" ppt
... http://www.translational-medicine.com/content/9/1/73 Page of 11 Figure Effect of PEP-1-SOD1 and PEP-1-CAT on Bcl-2 and Bax expression Bcl-2 and Bax expression was detected by Western blot as described in Materials and Methods (A), and quantified ... both of PEP-1-SOD1 and PEP-1-CAT to rats with myocardial ischemia-reperfusion injury CK CK-MB and cTnT are widely present in the cytoplasm of myocardial cells, and elevation of serum CK, CK-MB and ... University of Medicine, Shiyan, Hubei 442000, China 3Department of Physiology and Key Lab of human Embryonic Stem Cell of Hubei Province, Hubei University of Medicine, Hubei 442000, China 4Department of...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo sinh học: " Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... presence of the ligands to these chemokine receptors RANTES, MIP-1α and MIP-1β, all of which are ligands for CCR5, inhibit macrophage-tropic isolates, whereas SDF-1, the specific ligand for CXCR4, ... ratio) and transferred to a 24-well plate (105 cells per well in 200 ml of cultured medium) After 24 h of co-culture in the presence or absence of dexamethasone (10 mg/ ml), three random fields of ... in 200 µl of cultured medium) After 24 h of co-culture in the presence or absence of corticosteroids (dexamethasone or IM28) (10 µg/ml), three random fields of cells were photographed and the percentage...
Ngày tải lên: 18/06/2014, 22:20
báo cáo hóa học: " Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF" potx
... Effects of IL-6 and GM-CSF on phosphorylation of p44/42 MAPK, p38, and JNK To determine whether IL-6 and GM-CSF could activate MAPK pathways in BMECs as in the case of LPS phosphorylation of MAPKs ... Effects of antibodies to IL-6 and GM-CSF on LPS-induced changes in the permeability of BMECs to 131I-HIV-1 (A and C) and TEER (B and D) LPS (100 µg/mL) was added to the luminal chamber In panels A and ... the loading chamber Effects of LPS, IL-6, and GM-CSF on the expression of tight junction proteins To examine the effects of LPS, IL-6, and GM-CSF on the expression of tight junction proteins,...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học:" Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... presence of the ligands to these chemokine receptors RANTES, MIP-1α and MIP-1β, all of which are ligands for CCR5, inhibit macrophage-tropic isolates, whereas SDF-1, the specific ligand for CXCR4, ... ratio) and transferred to a 24-well plate (105 cells per well in 200 ml of cultured medium) After 24 h of co-culture in the presence or absence of dexamethasone (10 mg/ ml), three random fields of ... in 200 µl of cultured medium) After 24 h of co-culture in the presence or absence of corticosteroids (dexamethasone or IM28) (10 µg/ml), three random fields of cells were photographed and the percentage...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into human chondrocytes" docx
... rate of reduction of ferricytochrome c at 550 nm of 0.025 absorbance unit per minute Under these defined conditions, the amount of superoxide dismutase required to inhibit the rate of reduction of ... GTA C; and GAPDH antisense, CGT TCA GCT CAG GGA TGA CC Reactions were processed through 25 cycles of 30 seconds of denaturation at 94°C, minute of annealing at 55°C for GAPDH and 30 cycles of 45 ... to µM of fusion protein for hours, and the levels of protein transduced into the cells were analyzed by western blotting of protein extracted from the explants Faint but definite bands of trans-...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: " Persistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks" potx
... Thu Tram and Nguyen Van Ngai for follow-up of the exposed uninfected individuals, Annie David for technical assistance, Nathaniel Landau and Jay Levy for the gift of plasmids and vectors, and Ioannis ... (r2 were 0.845 and 0.826 for B195 and control, respectively) Statistical analysis and curve-fitting were performed with Sigmaplot software (Systat Software, Inc, CA, USA) Page of 12 (page number ... follows: [MFI after addition of ligand/MFI before addition of ligand] × 100] MFI values before ligand addition were arbitrarily set at 100% Owing to the large number of cells required, CD4 T cells...
Ngày tải lên: 13/08/2014, 09:20
Electronic communications mediated by metal clusters and pi conjugated systems 1
... Structure of 65 3.2.2 1H and 31P NMR of complexes 67 3.2.3 Electrochemistry of 69 3.2.4 Electronic absorption spectrum of 3+ 74 3.2.5 Structures of and 77 3.2.6 1H and 31P NMR of complexes and 81 ... Pt and Pd Centers and Acetylene and Vinylidene iv 4.1 Introduction 103 4.2 Objectives 104 4.3 Results and Discussion 108 4.3.1 Syntheses and Structures 108 4.3.2 1H and 31P NMR of complexes , and ... , and 115 4.3.3 Electrochemistry of the Binuclear Pt and Pd Compounds 119 4.3.4 Implications of the electrochemistry of the Complexes on the Nature of Metalligand Interactions 126 4.4 Conclusion...
Ngày tải lên: 17/09/2015, 17:17
Giáo án luyện tập cho ngưới mới tập (Từ 0 - 1 năm)- Upload by Trong Nhan.pdf
... chúng t ôi) Updat ing Sửa sonvalentine : 01-06-2011 lúc 02:45 PM hemattroi, lionmonkey, Akai90 and 77 others like this Canon EOS 1Ds Mark III,Lens:Canon EF 70- 200mm/2.8L IS II, Canon EF 85mm ... (sonvalentine - webthehinh.com) Sửa sonvalentine : 04-06-2011 lúc 08:59 AM hemattroi, y06a_ktanh, whitegun and 34 others like this Canon EOS 1Ds Mark III,Lens:Canon EF 70- 200mm/2.8L IS II, Canon EF 85mm ... CỦA TÔI HỮU ÍCH CHO BẠN Sửa sonvalentine : 01-06-2011 lúc 05:04 PM hemattroi, mrdang89, ikariam and 69 others like this Canon EOS 1Ds Mark III,Lens:Canon EF 70- 200mm/2.8L IS II, Canon EF 85mm...
Ngày tải lên: 27/08/2012, 09:21
Hacking Credit Card Version 1.0 --- Written by Hieupc
... :) Products Microsoft OLE DB Provider for ODBC Drivers error '80004005' [Microsoft][ODBC Microsoft Access Driver] The number of columns in the two selected tables or queries of a union query not ... http://www.nelcoproducts.com/shopping/shopdisplayproducts.asp?id=153%2 0and% 201=convert(int,(select%20top% 201%20table_name%20from%20information_schema.tables)) sp_password Microsoft OLE DB Provider for ODBC Drivers error '80040e07' [Microsoft][ODBC SQL ... Products Microsoft OLE DB Provider for ODBC Drivers error '80040e07' [Microsoft][ODBC SQL Server Driver][SQL Server]Syntax error converting the nvarchar value 'AdminUsers' to a column of data type...
Ngày tải lên: 09/10/2013, 12:20
Tài liệu Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway doc
... 30821065 and 30870559 from the China National Nature Sciences Foundation, 2006CB910703 from the Ministry of Sciences and Technology of China, and 07dz05907 from the Committee of Sciences and Technology ... the ability of troglitazone to reduce the number of large adipocytes and improve insulin sensitivity in obese Zucker rats [17,18] Akt-1 is one of the key regulators of cell survival, and many studies ... between PPARc activation and protein degradation requires further investigation In light of the apoptotic effect of PPARc in adipocytes, we conclude that PPARc is one of the key regulators involved...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide pptx
... modulation of RGS1 and RGS2 in BMDM after stimulation with LP and LPS in more detail, because regulation of RGS1 and RGS2 after activation of different TLR may modify the effects of G-protein ... by LP and LPS Thus, these results demonstrate that both BMDM and J774 cells express RGS1 and RGS2 mRNA and modulate expression after stimulation with LP and LPS Expression patterns of RGS1 and ... LPS and FSL-1 Involvement of TRIF in the upregulation of RGS1 and RGS2 mRNA The findings obtained from activation of TLR3 by stimulation with poly(I:C) indicate a different modulation of RGS1 and...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Phosphorylation of cyclin dependent kinase 4 on tyrosine 17 is mediated by Src family kinases pptx
... and tube assays The accumulation of C-YES in the precipitates correlated with the appearance of kinase activity in those samples The level of depletion of kinase activity mirrored the level of ... Detection of CDK4 Y17 phosphorylation (A) Alignment of the N-terminal amino acids of CDKs 1, 2, and showing the conserved tyrosine residue (vertical box) that corresponds to Y17 of CDK4, and the ... between fractions 40 and 47, at the start of the phosphate gradient (Fig 2C) Fractions 38–49 and a sample of the input were precipitated using deoxycholate and trichloroacetic acid, and the proteins...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
... NF-jB expression (Fig 2C, lanes and 4) and its DNA-binding activity (Fig 2D, lanes and 5) Phosphorylation of IKK-b and IjB-a was slightly reduced at 2.5 lm of apocynin and eradicated at 12.5 lm (Fig ... phosphorylation of IKKa ⁄ IKK-b heterodimer results in the phosphorylation and degradation of IjB-a, which then leads to the phosphorylation of NF-jB p65 subunit and renders the release of NF-jB p50 ... phosphorylation of IKK-b and IjB-a at 2, 10 and 30 of stimulation, respectively (Table and Fig 2E,F) An inhibitor for NADPH oxidase attenuates the movement of p47phox (Fig 5B), translocation of NF-jB...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Aggregative organization enhances the DNA end-joining process that is mediated by DNA-dependent protein kinase pdf
... Ku80, Ku70, histone H1 and 28 k proteins, regardless of the type of damage (Fig 3A, lanes 7–9) In the aggregation of linear and nicked DNA, and high mobility group box (HMGB)1 and HMGB2 proteins ... (lanes and 8) ssDNA induced a noticeable accumulation of 95 k and nucleolinD proteins in addition to DNA-PKcs, Ku80 and Ku70 (lane 9) On the other hand, a relaxed form of closed circular doublestrand ... fraction) and Mono Q columns (Mono Q fraction) Input DNA contained four forms of uX174 phage DNA, including 0.05 lg of HaeIII-digested linear duplex (LD), 0.05 lg of single-stranded circular (SSC) and...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Synergistic activation of signalling to extracellular signal-regulated kinases 1 and 2 by epidermal growth factor and 4b-phorbol 12-myristate 13-acetate pptx
... target genes expressed [16], and also affects the type of cellular response that is evoked [17,18] Activation of ERK is required for proliferation of fibroblasts [19] and constitutive ERK activation ... quasisteady state-concentration of 2–3· the sum of the concentration obtained after h of stimulation with only EGF and the concentration obtained with PMA only Apparently, EGF and PMA act synergistically ... maximum concentration of ERK-PP in the quasi-steady state-phase (after h of stimulation) and K is the EGF concentration at which ERK-PP is 50% of its maximal level Addition of PMA resulted in a...
Ngày tải lên: 19/02/2014, 16:20