13rα2 expression in pancreatic cancer cell lines
báo cáo khoa học: "ShRNA-mediated gene silencing of MTA1 influenced on protein expression of ER alpha, MMP-9, CyclinD1 and invasiveness, proliferation in breast cancer cell lines MDA-MB-231 and MCF-7 in vitro" pptx
Ngày tải lên :
10/08/2014, 10:21
... 9(MMP-9), cyclinD1, and on cancer cells invasion, proliferation and cell cycle cell in two cell lines were investigated Page of 11 Construction of shRNA expression vector for MTA1 According to principle ... breast caner cell lines MDA-MB-231 using Western blot analysis, in contrast, silencing MTA1 gene was no effect on protein expression of ER in ER-positive cell lines MCF-7 How to regulate expression ... protein expression of ER alpha, resulting in increase sensitivity of antiestrogens, as well as suppress the protein expression of MMP-9 and cyclinD1 in ER-negative human breast cancer cell lines...
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Báo cáo khoa học: The in vitro effects of CRE-decoy oligonucleotides in combination with conventional chemotherapy in colorectal cancer cell lines potx
Ngày tải lên :
07/03/2014, 15:20
... fetal bovine serum HCT116 and GEO cell lines were both wild-type p53, and SW620 lines were mutant p53 No antibiotics were used in our experiments, and all cell lines were incubated in a humidified ... CDO/chemotherapy combinations in GEO cells resulted in significant reductions in cell number This was further investigated by assessing BrdU incorporation Results confirmed the synergistic reduction in cell number, ... we assessed p21waf1 levels in GEO and HCT116 cell lines, and showed that combination therapy induced p21waf1 in the GEO cell line only (the cell line in which synergistic effects were observed)...
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Báo cáo sinh học: "MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells" pptx
Ngày tải lên :
18/06/2014, 19:20
... processes including development and cancer [16] EMT in cancer leads to the loss of cell- cell adhesion and cell polarity as well as altered cell- extracellular matrix interactions, resulting in invasion ... adenocarcinoma cell lines (Bic-1 and Seg-1), human gastric adenocarcinoma cell lines (AGS, AZ521 and KATOIII), colorectal adenocarcinoma cell lines (Caco-2 and DLD1), a human cervix epithelioid carcinoma ... Although Barrett’s adenocarcinoma is the most rapidly increasing cancer in Western countries [2], esophageal squamous cell carcinoma (ESCC) is still dominant in East Asia, including Japan [3] ESCC is...
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Báo cáo sinh học: " High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" potx
Ngày tải lên :
18/06/2014, 22:20
... GSK1070916 The cell line response data was compared to the mutation patterns in the cell lines, gene expression patterns and the karyotypes of the cell lines High chromosome number in the cell lines was ... lymphoma cell lines, of the cell lines were resistant to GSK1070916 and contained low chromosome number in the primary population of cells However, when in reviewing the ploidy content in the cell ... number in T-ALL cell lines WT Mutant NOTCH1 Total Diploid (~2n) High Modality (>3n) 12 14 Total 10 14 23 proliferating nature of the established cell lines in tissue culture Since cancer cell death...
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o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt
Ngày tải lên :
20/06/2014, 04:20
... GSK1070916 The cell line response data was compared to the mutation patterns in the cell lines, gene expression patterns and the karyotypes of the cell lines High chromosome number in the cell lines was ... lymphoma cell lines, of the cell lines were resistant to GSK1070916 and contained low chromosome number in the primary population of cells However, when in reviewing the ploidy content in the cell ... number in T-ALL cell lines WT Mutant NOTCH1 Total Diploid (~2n) High Modality (>3n) 12 14 Total 10 14 23 proliferating nature of the established cell lines in tissue culture Since cancer cell death...
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báo cáo khoa học: "Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines" pot
Ngày tải lên :
10/08/2014, 10:21
... observed for the combinations of FWGE and 5-FU (6 out of cell lines) and to a lesser extend for irinotecan and oxaliplatin (2 out of cell lines) Drug interaction for the remaining cell lines was additive ... induced by FWGE in a panel of cell lines In order to distinguish the mode of cell death induced by FWGE we treated a representative panel of human cancer cell lines with an IC90 of FWGE for 48 ... irinotecan or oxaliplatin was assessed in a panel of colon cancer cell lines The mode of drug interaction was analyzed by the method of Drewinko and the data summarized in table Overall, mainly...
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báo cáo khoa học: "Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate" docx
Ngày tải lên :
10/08/2014, 10:21
... effective in synchronizing DHDK12 cells in S phase than ara-C or aphidicolin Consequently, the efficacy of MTX in synchronizing cells in S phase was then tested in the HT29 cell line In HT29 cell line, ... France) cell lines Cell lines were cultured in DMEM medium containing 10% calf serum/penicillin (50 units/ ml)/streptomycin (50 μg/ml) at 37°C in 5% CO We used retroviral vectors carrying Escherichia-coli ... colon cancer cell lines used in this study, further investigations in more colon cancer cell lines are needed to draw definitive conclusion on the improvement of retroviral gene transfer after cell...
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Expression pattern of matrix metalloproteinases in human gynecological cancer cell lines ppt
Ngày tải lên :
28/03/2014, 14:20
... Additional file 1: MMP expression in gynecological cancer cell lines Methods Cell culture All the cell lines used were described in Table [20-45] and obtained from Cell Lines Service (Eppelheim, ... other MMPs in at least one of the cell lines For MMP-8, -12 and -21 only very weak mRNA expression could be observed in single cell lines Nine MMPs, which were present in most of the cell lines, were ... investigated the expression of all MMPs known in humans so far by measuring mRNA and protein level in twelve gynecological cancer cell lines commonly used in experimental research We examined cell lines...
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báo cáo hóa học:" Aberrant STYK1 expression in ovarian cancer tissues and cell lines" pdf
Ngày tải lên :
20/06/2014, 07:20
... of estrogen receptors and STYK1 in ovarian cancer cell lines We detected ER- RNA expression in ovarian cancer cell lines SKOV3, CaOv3, and OvCar3 (Fig 2A) Cell lines HS832, OvCar5, OvCar8 and ... ovarian cell line and the remaining cell lines were derived from ovarian cancer cell lines (A) Ethidium bromide-induced fluorescence of RT-PCR amplification product from ovarian tumor RNA using primers ... and STYK1 protein was detected at varying levels in each cell line (Fig 2B) Estradiol and GPR30-specific G-1 induce STYK1 RNA but not protein expression in ovarian cancer cell lines RNA isolated...
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Báo cáo khoa học: "The combination effect of sodium butyrate and 5-Aza-2''''-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines" pot
Ngày tải lên :
09/08/2014, 04:21
... increased radiosensitivy in prostate cancer cell lines In this experiment, RKO cell lines showed a 56% survival rate with radiation alone, while with SB, 47% survived In MCF-7 cell lines, radiation alone ... radiosensitivity in MCF-7 and RKO cell lines In RKO cell lines, which are in a relatively hypermethylated state, the effect of 5-aza-DC was similar to that of SB; in MCF-7 cell lines, the effect ... Materials and methods Cell line culture and reagents Human colon cancer cell lines RKO (ATCC, USA), breast cancer cell line MCF-7 (KCLB, Korea), and normal colon cell line DDC-112 CoN (ATCC)...
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báo cáo khoa học: "EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pptx
Ngày tải lên :
10/08/2014, 10:21
... for applying COX-2 inhibitor in adenocarinoma patients receiving tyrosine kinase inhibitor (TKIs), as COX-2 inhibitor offered synergistic antitumor effects with TKI [21] Although COX-2 expression ... the EGFR results in activation of downstream signaling pathways, including the Ras-Raf-MKKextracellular signal-regulated kinase (ERK) and lipid kinase phosphatidylinositol 3-kinase/Akt pathways ... greater in patients with EGFR over -expression than in EGFR negative group (P = 0.006) This might indicate that EGFR was not only involved in cancer genesis but also played an important role in cancer...
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báo cáo khoa học: " Correction: EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pps
Ngày tải lên :
10/08/2014, 10:21
... 90 Paracancerous tissue 14.3 P < 0.05 Reference Li Feng, Liu Yongmei, Chen Huijiao, Liao Dianying, Shen Yali, Xu Feng, Wang Jin: EGFR and COX-2 protein expression in non-small cell lung cancer ... West China Hospital, Sichuan University, PR China 2Department of Pathology, West China Hospital, Sichuan University, PR China Table (corrected table five) COX-2 expression in tumor and paracancerous ... clinical features Journal of Experimental & Clinical Cancer Research 2011, 30:27 doi:10.1186/1756-9966-30-32 Cite this article as: Li et al.: Correction: EGFR and COX-2 protein expression in...
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Tài liệu Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR pptx
Ngày tải lên :
15/02/2014, 04:20
... samples and low in SQ samples In our study, all three AD cell lines showed a robust increase in S100P expression, while the three SQ cell lines showed less or no increase Taking our data and ... close in PC1, PC2, and PC3, whereas one LC cell line, 86-2, showed intermediate separation in PC1 and PC3 The three SC cell lines were close to each other Two close LC cell lines and three SC cell ... STMN1 influenced cell motility [24] and S100P was associated with cell growth [25] STMN1 and S100P may work in SC cell lines and AD cell lines, respectively, in this study The third connection including...
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Báo cáo khoa học: Interaction of G-rich GT oligonucleotides with nuclearassociated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines potx
Ngày tải lên :
16/03/2014, 13:20
... binding to nucleolin (black arrow) The competition experiments in UV cross-linking assays with the GT-recognizing proteins confirmed the results obtained with the total nuclear-enriched proteins: ... taking into account the different binding ability vs the same cytotoxicity Although a different intracellular localization could explain differences in antiproliferative effect, the protein binding ... oligodeoxynucleotides in human cancer cells DNA Cell Biol 22, 685–696 15 Scaggiante B, Morassutti C, Dapas B, Tolazzi G, Ustulin F & Quadrifoglio F (1998) Human cancer cell lines growth inhibition by...
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Báo cáo khoa học: An estrogen receptor a suppressor, microRNA-22, is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples pptx
Ngày tải lên :
22/03/2014, 21:20
... included in Table S2 Cell lines and cultures Five breast carcinoma cell lines were obtained from the Cell Resource Center of Peking Union Medical College (Beijing, China) and maintained in our laboratory ... levels in breast cancer cell lines and surgical specimens It was interesting to find that downregulation of miR-22 expression occurs frequently, not only in ERa-positive human breast cancer cell lines, ... downregulation of miR-22 expression in ERa-positive breast cancer cell lines and tumor specimens (A) For breast cancer cell lines, the expression levels of mature miR-22 were determined by quantitative...
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Báo cáo hóa học: " CCL20/CCR6 expression profile in pancreatic cancer" docx
Ngày tải lên :
18/06/2014, 16:20
... protein expression in benign, pre-malignant and malignant pancreatic tissues CCL20 protein was weakly expressed in normal pancreatic tissue and in PA and CP specimens In PCA the CCL20 protein expression ... primarily found in pancreatic islet cells and rather sporadically in epithelial cells of pancreatic ducts as CCL20 in pg/ml per mg total protein A 15000 * shown in Figure 3A and 3B In CP tissues ... mal pancreatic tissues analyzed In PCA tissues the CCL20 transcript was detected in moderate to high levels [14] and expression of the CCL20 protein was observed in cancer cells within the pancreatic...
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báo cáo khoa học: " Platinum resistance in breast and ovarian cancer cell lines Niels Eckstein" pptx
Ngày tải lên :
10/08/2014, 10:21
... Oxaliplatin (Eloxatin®) (Figure 1) are first-line anti -cancer drugs in a broad variety of malignancies, for instance: ovarian cancer, testicular cancer and non small cell lung cancer Cisplatin is inactive ... For instance, hepatocellular carcinoma cells with elevated thioredoxin levels are resistant to Cisplatin, but not to the antracyclin Doxorubicin [39] However, bladderand prostate cancer cell lines ... microRNA expression in three cisplatin resistant germ cell tumour cell lines compared to their non-resistant, cisplatin sensitive counterparts [20] The authors found a significant increase in the expression...
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báo cáo khoa học: " Galectin-3 and cyclin D1 expression in non-small cell lung cancer" doc
Ngày tải lên :
10/08/2014, 10:21
... 1) In squamous cell carcinoma (SCC) galectin-3 expression was positive in 11 from 24 tumor specimens (45.83%), in adenocarcinoma in from 15 (26,67%), in large cell carcinoma in from (50%) and in ... squamous cell carcinoma in 24 patients, adenocarcinoma in 15 patients, large cell carcinoma in patients and non- small cell lung cancer of unspecified type in patients Based on the TNM staging system: ... the expression of proteins involved in regulation of cell proliferation remains promising Cellular proliferation is regulated by protein complexes composed of cyclins and cyclin-dependent kinases...
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Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
Ngày tải lên :
14/08/2014, 08:20
... colony-stimulating-factor; HNSCC, head and neck squamous cell carcinoma; IGF, insulin-like growth factor; IκB, inhibitor kappaB; IKK, inhibitor-kappaB kinase; IL, interleukin; IL-R, interleukin receptor; ... Effects of interleukin-1alpha, interleukin-1 receptor antagonist, and neutralizing antibody on proinflammatory cytokine expression by human squamous cell carcinoma lines Cancer Res 1998, 58(16):3668-3676 ... status and all 10 p53 cell lines used (wt+mt), which include the cell lines with wild-type p53-deficient status Similarly, 117 genes were overlapping between the group of cell lines with mutant p53...
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