● object that phản đối rằng

... us that it wouldn’t cost more ● object that : phản đối e.g : “It won’t cost more,” Tom assured us “But it’ll take longer,” Bill objected Tom assured us that it wouldn’t cost more But Bill objected/ ... He answer that he hadn’t ● argue that : tranh cãi e.g : “But a car is not strong enough to open the fridge” he said He argue that a car was not strong enough to open the fridge ● claim that : cho ... cụ thể a) Tường thuật lời trần thuật ● admit that : thú nhận e.g “ It was me who took money.” He admitted that he had taken the money ● answer that/ reply that : trả lời e.g “ Did you go out last...

Ngày tải lên: 17/02/2015, 04:00

... to 50% more, exogenous insulin to normalize glucose Using the values reported, one could argue that the beta-cell had sufficient capacity to meet a peak demand of 0.13 U/kg/h for 5.8 days (RF ... will be essential in guiding future treatment strategies Competing interests The authors declare that they have no competing interests Acknowledgements MSDA is presently conducting an on-going...

Ngày tải lên: 13/08/2014, 16:20

... your lack of energy during the day You will find that once you start eating properly you’ll have so much more vigour that you’ll no longer need all that caffeine If you are considering giving up ... experience difficulties sleeping that leave them waking up unrefreshed at least two mornings a week And around half of that number felt 38 so tired during the following days that they believed it affected ... attendant wooziness on waking that comes with the later stages It’s something that cats and old people have known for ages; now all you’ve got to is get your boss to see it that way The secrets to...

Ngày tải lên: 06/03/2014, 00:22

Ngày tải lên: 21/03/2014, 22:00

... seller will also be concerned that the longer the deal is pending, the longer that buyer has to conduct due diligence and the longer that buyer has to uncover issues that it can use to back out ... companies Many senior executives realize that now is their opportunity and that the window of opportunity is wider than it has ever been It is also likely that deals will continue to grow in size ... any remedy that an injured plaintiff might have had This has been interpreted to mean that acquirer actually played some role in the destruction of plaintiff ’s remedies This means that all, or...

Ngày tải lên: 23/03/2014, 12:20

... the needs of training for workforce in Mekong Delta for the upcoming period Objects of study and teachers of study 3.1 Objects of study To manage the development of lecturers in vocational colleges ... organizing-controlling (how to impact) of the subject to the object management to manage the effective implementation of organizational goals that has been set 1.2.3.2 Development Management of lecturer ... evaluating must be objective, open, democratic, balance to make them effective 1.6 The factors influence development management lecturer staff of the vocational colleges 1.6.1 Objective factors...

Ngày tải lên: 25/07/2014, 14:39

... half-life for both enantiomers of methadone was measured, suggesting rapid metabolism A second factor that possibly contributes to interindividual sensitivity to methadone is the permeability glycoprotein ... including intestine, liver and bloodbrain barrier [7] Genetic polymorphisms have been described for PGP that can contribute to differences in blood concentrations of methadone [4] More importantly, a ... in genetically mediated sensitivity to methadone-induced respiratory depression Another factor that may be involved in methadone pharmacokinetics is the strong blood binding of methadone to plasma...

Ngày tải lên: 13/08/2014, 03:20

... Jurkat cells to that induced by cross-linking of the T cell antigen receptor, despite the absence of the c-chain A possible explanation for this is provided by the observation that the CD3 chain ... of GPVI into COS-7 and K562 cells, respectively, that GPVI is expressed at the cell surface independently of the FcR c-chain This is a property that has previously been described for the GPVI-related ... [21], raising the possibility that in vivo, unlike in cell lines, GPVI may be degraded in the absence of the FcR c-chain This may reflect a specific pathway of degradation that prevents expression of...

Ngày tải lên: 22/02/2014, 07:20

... competitive inhibitor Pattingre et al [14] showed that autophagosome content was negatively correlated with the amount of Bcl-2 that interacted with Beclin 1, and that Bcl-2 binding of Beclin interfered ... content) revealed the surprising finding that Beclin 1DBcl2BD suppressed autophagy This was in contrast to the studies of Pattingre et al [14], who showed that in cancer cells, Beclin 1DBcl2BD, ... fluorescence in cells expressing GFP–Bcl-2-ER was similar to that of GFP–Bcl-2-wt (results not shown), thus allowing us to conclude that differential effects of Bcl-2-ER were due to its localization...

Ngày tải lên: 07/03/2014, 09:20

... Table show that the IC50 values of these two single mutants were similar and that they lay between the IC50 values of the human and pig CPT1B wild-type enzymes These results indicate that a single ... explanation for this is that, in the case of CPT1B, the docking of the N-terminal fragment might differ from that of the established model A further explanation for our data might be that Asp17 interacts ... characterized for human CPT1B [20,22] Figure 1B also shows that a D28 N-terminal deletion created a similarly insensitive enzyme (IC50=39.19lm), indicating that the low sensitivity to malonyl-CoA of the...

Ngày tải lên: 16/03/2014, 04:20

... we showed that MPP3 forms protein complexes and colocalizes with MPP5 at the SAR of the OLM We also showed that MPP3 does not bind directly to CRB1 We and others showed previously that MPP5 interacts ... 3M–Q) Thus, taking into account our previous results that showed colocalization of MPP5 with CRB1 at the SAR of the OLM [22,24], we deduce that MPP3, MPP5 and CRB1 colocalize at the SAR MPP3 colocalizes ... of Mpp3 in mouse retina Note that unlike in the case with human retinal lysates, the 37 kDa band is not detected observed immunoreactivity in the OPL similarly to that described for the rat retina...

Ngày tải lên: 16/03/2014, 13:20

... indicate that BFA-treated cells failed to recycle a fraction of endocytosed R24 antibody A simple interpretation of these results is that R24 antibody may recycle via a single route and that BFA ... suggesting that monensin perturbs the departure of R24 from the recycling endosome and hence that endosomal acidification is probably required for the formation of the carrier structures that move ... sensitive to monensin It was previously proposed that endosomal acidification is a prerequisite for the actual formation of the carrier structures that move the TGN proteins (TGN38 or furin) from...

Ngày tải lên: 16/03/2014, 13:20

... (data not shown), indicating that almost all C-terminal tyrosine was substituted by 3-nitrotyrosine The possibility that the disappearance of nitrotyrosinated tubulin that occurred after elimination ... using antibody to nitrotyrosinated a-tubulin, showed that the tyrosine analogue was incorporated into a unique protein with mobility identical to that of a-tubulin (Fig 1B) Similarly, radioactive ... observation that pancreatic carboxypeptidase A (which in vitro efficiently removes C-terminal tyrosine from tubulin) cannot release previously incorporated 3-nitrotyrosine, it was proposed [11] that...

Ngày tải lên: 17/03/2014, 10:20

... show that MREa has the greatest effect on WD gene promoter activity Several studies have reported that MREa in the promoter of the MT gene possesses transcriptional regulatory activity and that ... [11,33,38,39] These findings suggest that transcriptional activator proteins that regulate expression of the WD gene may bind to MREa Identification of proteins that interact specifically with MREa ... has been proposed that the WD protein acts as a copperspecific pump that mediates the export of copper from the cytosol, similar to the P-type ATPase [14] On the basis of the fact that MREs mediate...

Ngày tải lên: 17/03/2014, 23:20

... a misconception that hacking is done mostly for personal gain, but that is probably one of the least of the reasons More often than not, hackers are breaking in to something so that they can say ... been involved with Internet technology since 1976 and says that with ColdFusion as his development tool of choice, he no longer believes that the Web has limits Samantha Thomas has been programming ... attack the forms in your application Typical ColdFusion action pages that accept input from forms make a cursory check to see that variables in the form scope have been initialized, or check for...

Ngày tải lên: 25/03/2014, 11:18

... the way that the hacker has walked to become one It is impossible to defend one’s work without first appreciating the adversary that attacks that work.We take a journey along the path that evolved ... interesting to note that that issue is no longer available to the general public.) The problem with analog circuit tone generators was that they drifted over time and use, meaning that they had to ... engineering of products that have licenses that forbid it.The MPAA it doing its best to outlaw DeCSS, which is a piece of software that allows one to defeat the brain-dead crypto that is applied to...

Ngày tải lên: 25/03/2014, 11:18

... cure a host of diseases Clinical studies are suggesting that traditional medicine has been on the right track Nutritional analyses show that the leaves are very high in protein and contain all ... are one of the best plant foods that can be found.” - Dr Frank W Martin, in Survival and Subsistence in the Tropics “A major advantage to Moringa is the fact that it is a local resource This ... www.moringanews.org/biblio_en.html 17 HOW YOU CAN HELP: If studies show that the nutrients in Moringa leaves are sufficiently bioavailable or that the medicinal benefits even come close to traditional claims,...

Ngày tải lên: 31/03/2014, 22:20

... your expenses so that you produce enough income to fund a plan—your creditors or the trustee are likely to object on the ground that your plan isn’t feasible And even if there is no objection, it ... any of your debts that qualify for discharge are wiped out at the end If any balance remains on a debt that doesn’t qualify for discharge, you will continue to owe it (The debts that qualify for ... automatic stay for a particular creditor if that creditor convinces the court that the stay isn’t serving its intended purpose: to freeze your assets and debts so that the court can deal with them This...

Ngày tải lên: 18/04/2014, 14:03