... Since the inhibition of the activity of NFB by parthenolide did not block the increase in the level of F11R mRNA induced by IFNg, we examined whether the IFNg-induced increase in the level of F11R ... for the progression of this chain of events by the use of two blockers of mRNA synthesis: Actinomycin, an overall inhibitor of RNA synthesis, and F11R-siRNA, a specific inhibitor of the synthesis ... significantly, followed by increased denovo synthesis of the F11R-protein and the insertion of newly-synthesized F11R molecules into the luminal surface of the endothelium [18] The present study provides...
Ngày tải lên: 18/06/2014, 19:20
... technique for the simultaneous determination of macrolides The fragmentation patterns provide the confirmatory information of macrolides The relevance of these studies for the determination of macrolide ... is used for the back-calculation of the drug concentration in the sample, y=mx + b (m, the slope; b, the intercept; x, the amount; y, the area) b is the residual standard deviation of calibration ... (Fig 3) The appearance of fragmentation ions was due to the dissociation of amino or sugar moieties on the structure of drugs The m / z 5 76. 5 and 67 9.5 in mass spectra of erythromycin and roxithromycin...
Ngày tải lên: 07/08/2014, 15:20
Xác định lượng vết Selen bằng phương pháp Von- Ampe hòa tan catot xung vi phân khi có mặt Rh = Ultratrace determination of Selenium (IV) by cathodic stripping voltammetry tn the presence of Rhodium
... 37.50±2 ,68 2,14±0,19 67 ,50±3 ,66 2,88±0,19 42,33±2,99 2,18±0,19 902.503±9 ,66 55.05±2, 96 135,83 6, 09 6, 63±0, 36 999,17± 26, 47 57,05±1,85 45,00±4, 06 2,88±0,32 8/12/2002 15,83±2,30 0,85±0,40 22/12/2002 1 266 ,67 ±33,40 ... 83.0 1.48 39.9 68 .7 81.4 67 .0 57.4 1.8 31.3 56. 3 61 .0 53.0 42.2 38.2 9.9 26. 4 48.0 37.4 31.0 32.7 2.25 20.2 35.1 42.5 30.1 23.5 23.0 2 .65 11.5 22.2 23.0 16. 2 13.3 12.9 3. 06 6.9 11 .6 9 .6 1.01 OppmRh ... Ep(mV) ÌP 200mV/s Ep(mV) ip b Catot -591 4 96. 6nA -591 63 1.InA -588 715.2nA Anot a -533 35.7nA -534 36. 2nA -5 36 35.4nA Catot -723 10 .62 7KA -721 4.992^A -720 4.436jiA Anot 124 ' ^ \ i' ~S//'~" 11'' \.m...
Ngày tải lên: 12/03/2015, 14:47
DEVELOPING SOFTWARE TOOLS FOR STRUCTURE DETERMINATION OF LARGE PROTEINS BY NMR SPECTROSCOPY
... GLU GLU CA CB CA CB H N CA CB H 56. 304 33.3 36 62.145 69 .7 36 8.2 36 1 16. 334 56. 124 31.485 8.5 76 38 As seen from the example, the shifts file usually consists of multiple lines, and each line contains ... energy difference between the two states, and therefore the strength of the magnetic field The higher the B0, the bigger the ΔE, and the more spins that will contribute to the signal This fact explains ... proportional to the inverse sixth power of the distance between the two interacting spins, and therefore falls off rapidly as the distance increases This extreme sensitivity of the NOE to the internuclear...
Ngày tải lên: 04/10/2015, 15:45
Tài liệu Audit of Contract Management by the Sectors doc
... case, we asked the PWGSC contracting officer why the 10% profit invoiced by the subcontractor had been approved when there was no mention of it in the basis of payment The contracting officer told ... that despite the fact that no mention of profit was made in the basis of payment, it was the intention of the contracting authority to authorize such a profit The PWGSC contracting officer told ... shows that the only evidence of the verification carried out by the sector finance clerks is their initials and a tick mark (√ ) The tick marks did not enable us to determine the nature of the verification...
Ngày tải lên: 17/02/2014, 21:20
Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx
... Total sterol ste20D 15.21 0 .62 0.48 0.28 16. 59 20.1 0.84 0 .64 0.45 22.03 ± ± ± ± ± 0 .66 0.14 0. 16 0.09 0.59 ± ± ± ± ± cla4D 1 .67 0. 06 0.04 0.15 1 .65 Results Cells lacking either STE20 or CLA4 exhibit ... amounts of SE (A) Quantification of SE in cell polarity mutants Cells of the indicated strains were grown to stationary phase and then lipids were extracted and separated by TLC The amount of SE of the ... solution consisting of 0 .63 g of MnCl2Æ4H2O, 60 mL of water, 60 mL of methanol and mL of concentrated sulfuric acid, briefly dried and heated at 100 °C for 20 SE were then quantified by densitometric...
Ngày tải lên: 18/02/2014, 13:20
Báo cáo khoa học: Dual modulation of prothrombin activation by the cyclopentapeptide plactin pptx
... fluorescence of prothrombin in the presence of Ca2+ was significantly lower (6. 6%, P < 0.01) than in the absence of Ca2+ Plactin D increased the internal fluorescence by 7.7% (P < 0.001), even under these ... monitored kinetically at 37 °C From the slope of the plots of A405 versus t2 [ 26] , the initial velocity of thrombin generation was calculated In the SDS ⁄ PAGE assay for the prothrombinase-catalyzed ... for the indicated times in buffer F (DAPA was included to inhibit the feedback proteolysis of prothrombin by the generated thrombin) The reaction was stopped by the addition of an equal volume of...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Distinguishing between different pathways of bilayer disruption by the related antimicrobial peptides cecropin B, B1 and B3 pptx
... suggested that the N-terminal a-helix of CB1 is located on the surface of the lipid bilayers, whereas the C-terminal a-helix of CB1 is embedded below the surface of the lipid bilayers These conclusions ... DSC analysis of the effect of peptides on PtdEtn/PA LUV thermotrophic phase behaviour The effect of CB, CB1 and CB3 on the thermotrophic phase behaviour of LUVs is shown in Fig The phase-transition ... sample loss caused by the adsorption of hydrophobic molecules to the surfaces of the flow system of the BIAcore instrument Peptides dissolved in HBS-EP buffer are not lysed by the liposomes Avidin...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... peptide The percentage of degradation was calculated by comparing the area of the peaks of the intact peptide at t ¼ and t ¼ 60 Binding assays Binding assays were carried out at 22 °C with either ... structures of the b-amino acids that best fit are shown in Fig They all correspond to gauche(+) values of the h angle The methyl group of b2-HAla occupies a position close to that of CH2b of Pro or the ... the expense of a minimal decrease in its activity HGly (named by the authors b-alanine) has been previously introduced in the sequence of the C-terminal heptapeptide of NKA, another peptide of...
Ngày tải lên: 08/03/2014, 08:20
REGULATION OF INTEREST RATE BY THE STATE BANK OF VIETNAM (SBV) potx
... 8. 76 8 .64 9. 06 9.00 9.18 9.24 9.78 9.72 9. 96 It is also noted that the interest rates of all state-owned banks are nearly same On the other hand, the utility package offered by the banks to the ... instead of lowering the interest rate according to the policy adopted by the Conference of Bankers at the beginning of the year, the State Bank preserved the status quo on the grounds that the inflation ... determined by the central bank and announced on the basis of real situation and targets of the national monetary policy The point 12, Article of the Law on the State Bank of Vietnam stipulates: " The...
Ngày tải lên: 15/03/2014, 01:20
Listening and Learning: the Ombudsman’s review of complaint handling by the NHS in England 2010-11 doc
... 237 14 1,381 16 39 173 96 614 247 21 1,222 Unknown SHA 270 69 7 84 428 41 265 10 1,808 Total 2 26 707 2,581 1,3 56 6,924 18 97 2,714 240 15, 066 88 Figure shows a breakdown of the type of body complained ... Investigated complaints reported on: not upheld % 62 66 20 10 42 16 16 32 16 39 19 20 46 29 26 84 28 75 34 16 43 31 48 24 21 21 67 29 36 18 27 64 0 1 1 0 1 0 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 ... periods of great anxiety about the terminal illness of a loved one or the health of a young child In one case, the decision to remove the patient was made by the member of staff involved in the altercation...
Ngày tải lên: 19/03/2014, 07:20
Báo cáo Y học: Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase pot
... Production of glyoxal in lipid peroxidation by MnP (Eur J Biochem 268 ) 61 15 without the aid of the other oxidizable substrates We now report the formation and chemiluminescent chain reactions of glyoxal ... production of glycol aldehyde, a substrate of GLOX [6] The glycol aldehyde formed by this process was converted to oxalate with the production of 2.8 equivalent of H2O2 Therefore, they proposed ... with an 61 16 T Watanabe et al (Eur J Biochem 268 ) incident slit width of 1.0 mm The wavelength range of the spectrometer was 370– 820 nm Experimental conditions are described in the legend of each...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo khoa học: Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome ppt
... to the reaction containing the TAP–Rrp43p complex increases the RNase activity of the exosome by 16% (Fig 7A; lane 7) Addition of 20 and 30 pmol Nop53p further increased the RNase activity of the ... polyadenylation of the RNAs that are substrates for degradation by the exosome [22] As depletion of Nop53p leads to the accumulation of polyadenylated pre-rRNAs, this raises the question of whether Nop53p ... in the nucleolus, whereas the C-terminal portion of Nop53p might interact with the proteins in the pre -60 S complex, but is less concentrated in the nucleolus These results raised the question of...
Ngày tải lên: 30/03/2014, 04:20
báo cáo hóa học:" Transcriptional regulation of bone formation by the osteoblast-specific transcription factor Osx Chi Zhang" pptx
... expression of type I collagen (Col1a1) in the condensed mesenchyme of the membranous skeleton and the periosteum and mesenchyme of the endochondral skeleton is severely reduced Expressions of the osteoblast-specific ... gain -of- function mutants of Lrp5 lead to high bone mass syndrome in patients [ 16] and in mice [17] The Wnt signaling antagonist Dkk1 prevents the activation of Wnt signaling by binding to LRP5 /6 ... determinant of craniofacial patterning and osteoblast differentiation Cell 20 06, 125:971-9 86 11 Jones DC, Wein MN, Oukka M, Hofstaetter JG, Glimcher MJ, Glimcher LH: Regulation of adult bone mass by the...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo hóa học: "Synthesis of SnS nanocrystals by the solvothermal decomposition of a single source precursor" pdf
... Values of the optical band gap for the samples were obtained by the extrapolation of the linear region of the plot of (ahv)1/2 against photon energy (hv) as shown in Fig 4(c) Clearly, the absorption ... to be dependent on the nature of the stabilizing agents used in addition to the thermal conditions of the preparation Isotropic and anisotropic growth of SnS NCs is achieved by use different capping ... g, 40%) For the synthesis of SnS NCs, the mixture of 0. 16 g Sn(Et2Dtc)2, ml oleic acid and ml of oleylamine contained in a 50 ml three neck flask (1) was degassed and purged by argon The solution...
Ngày tải lên: 22/06/2014, 22:20
Báo cáo hóa học: " Synthesis of SnS nanocrystals by the solvothermal decomposition of a single source precursor" ppt
... Values of the optical band gap for the samples were obtained by the extrapolation of the linear region of the plot of (ahv)1/2 against photon energy (hv) as shown in Fig 4(c) Clearly, the absorption ... to be dependent on the nature of the stabilizing agents used in addition to the thermal conditions of the preparation Isotropic and anisotropic growth of SnS NCs is achieved by use different capping ... g, 40%) For the synthesis of SnS NCs, the mixture of 0. 16 g Sn(Et2Dtc)2, ml oleic acid and ml of oleylamine contained in a 50 ml three neck flask (1) was degassed and purged by argon The solution...
Ngày tải lên: 22/06/2014, 22:20
Designation: C 115 – 96a - Fineness of Portland Cement by the Turbidimeter1 pps
... shall be mounted over the photoelectric cell The front of the hood shall be 2 56 mm (1 1⁄ 16 in.) in front of the face of the cell The face of the photocell shall be parallel to the tank faces within ... mounted on the cabinet The zero of the scale shall indicate that position at which the center lines of the slots for the light beam are at the same elevation as the surface of the liquid in the tank ... adjusted so that the turbidity of the suspension may be determined at any desired depth The center of the light source, the heat absorbing device, the photocell, the center of the slots of the metal...
Ngày tải lên: 10/07/2014, 23:20
Designation: C 184 – 94e1 - Fineness of Hydraulic Cement by the 150-µm (No. 100) and 75-µm (No. 200) Sieves1 ppt
... 60 °, through the center If one of the lines is marked with an arrowhead and the habit of starting with this point under the right hand has been formed, one can easily follow the progress of the ... and the beads lodged in the meshes are difficult to remove Tapping the frame of the sieve and gentle brushing of the cloth from the underside will aid in recovering all the beads and keep the ... important that the sample for calibration be of the same typical fineness as the range at which the sieve is to be used Determine the percent residue of the test material on each of the three sieves,...
Ngày tải lên: 10/07/2014, 23:20
Designation: C 430 – 96 - Fineness of Hydraulic Cement by the 45-µm (No. 325) Sieve1 pps
... at the rate of one motion per second in the spray The bottom of the spray nozzle should extend below the top of the sieve frame about 12 mm (0.5 in.) Immediately upon removing the sieve from the ... (0.51-mm) Holes Calculation 7.1 Calculate the fineness of the cement to the nearest 0.1 % as follows: proportional to the amount of residue Example of Determination of Sieve Correction Factor: Residue ... that determination of the validity of any such patent rights, and the risk of infringement of such rights, are entirely their own responsibility This standard is subject to revision at any time by...
Ngày tải lên: 10/07/2014, 23:20