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Chemotherapy induced constipation and diarrhea pathophysiology, current and emerging treatments

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Chemotherapy induced constipation and diarrhea pathophysiology, current and emerging treatments

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...McQuade et al Chemotherapy- Induced Constipation and Diarrhea reported to last as long as 10 years post-treatment (Denlinger and Barsevick, 2009) Persistent and severe chemotherapyassociated Diarrhea. .. Richardson and Dobish, 2007) and constipation, with Frontiers in Pharmacology | www.frontiersin.org November 2016 | Volume | Article 414 McQuade et al Chemotherapy- Induced Constipation and Diarrhea. .. opioid induced bowel dysfunction (Webster et al., 2008) Current Treatments for Chemotherapy- Induced Constipation The management of constipation can be divided into general interventions and therapeutic

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Mục lục

  • Chemotherapy-Induced Constipation and Diarrhea: Pathophysiology, Current and Emerging Treatments

    • Introduction

    • Chemotherapy-Induced Diarrhea

      • Pathophysiology of Chemotherapy-Induced Diarrhea

      • Current Treatments for Chemotherapy-Induced Diarrhea

        • Loperamide

        • Octreotide

        • Deodorised Tincture of Opium

        • Chemotherapy-Induced Constipation

          • Pathophysiology of Chemotherapy-Induced Constipation

          • Opioid-Induced Constipation

          • Current Treatments for Chemotherapy-Induced Constipation

            • Bulk-Forming Laxatives

            • Osmotic Laxatives

            • Emollient (Stool Softener) Laxatives

            • Stimulant Laxatives

            • Lubricant Laxatives

            • Rectal Laxatives

            • Emerging And Potential Treatments For Cid And Cic

              • Chloride Channel Inhibition and Activation

              • Cannabinoid Receptor Inhibition and Activation

              • Guanylate Cyclase C Activation

              • Probiotics, Antibiotics, and -glucuronidase Inhibitors

              • Conclusion

              • Author Contributions

              • Funding

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