Handbook of local anesthesia 6th edition

www.pdflobby.com www.pdflobby.com TABLE 4-4  Maximum Recommended Dosages (MRDs) of Local Anesthetics Available in North America TABLE 4-17  Duration of Pulpal and Soft Tissue Anesthesia for Available Local Anesthetics DURATION (APPROXIMATE MINUTES) MANUFACTURER’S AND FDA (MRD) Local Anesthetic Articaine With vasoconstrictor Bupivacaine With vasoconstrictor With vasoconstrictor (Canada) Lidocaine With vasoconstrictor Mepivacaine No vasoconstrictor With vasoconstrictor Prilocaine No vasoconstrictor With vasoconstrictor mg/kg mg/lb MRD, mg 7.0 3.2 None listed None listed 2.0 None listed 0.9 90 90 7.0 3.2 500 6.6 6.6 3.0 3.0 400 400 8.0 8.0 3.6 3.6 600 600 CALCULATION OF MILLIGRAMS OF LOCAL ANESTHETIC PER DENTAL CARTRIDGE (1.8 mL CARTRIDGE) Local Anesthetic Percent Concentration mg/mL × 1.8 mL = mg/Cartridge Articaine Bupivacaine Lidocaine Mepivacaine 0.5 2 40 20 20 30 40 72* 36 36 54 72 Prilocaine MRD, Maximum recommended dose *Cartridges of some drugs in the United States read, “1.7 mL each.” The actual volume of all local anesthetic cartridges is approximately 1.76 mL Drug Formulation Mepivacaine 3% (infiltration) Prilocaine 4% (infiltration) Prilocaine 4% (nerve block) Articaine 4% + epinephrine 1 : 200,000 Lidocaine 2% + epinephrine 1 : 50,000 Lidocaine 2% + epinephrine 1 : 100,000 Mepivacaine 2% + levonordefrin 1 : 20,000 Articaine 4% + epinephrine 1 : 100,000 Prilocaine 4% + epinephrine 1 : 200,000 Bupivacaine 0.5% + epinephrine 1 : 200,000 Pulpal Soft Tissue 5-10 10-15 40-60 45-60 90-120 60-120 120-240 180-240 60 180-300 60 180-300 60 180-300 60-75 180-300 60-90 180-480 >90 240-720 www.pdflobby.com www.pdflobby.com This page intentionally left blank www.pdflobby.com Stanley F Malamed, DDS Professor of Anesthesia and Medicine School of Dentistry University of Southern California Los Angeles, California with 441 illustrations www.pdflobby.com www.pdflobby.com To Beverly, Heather, Jennifer, and Jeremy, and the next generation: Matthew, Rachel, Gabriella, Ashley, Rebecca, Elijah, and Ethan www.pdflobby.com This page intentionally left blank www.pdflobby.com Contributors Daniel L Orr II, BS, DDS, MS (Anesthesiology), PhD, JD, MD Professor and Director Oral and Maxillofacial Surgery and Advanced Pain Control University of Nevada Las Vegas School of Dental Medicine Las Vegas, Nevada Clinical Professor Oral and Maxillofacial Surgery University of Nevada School of Medicine Las Vegas, Nevada Mark N Hochman, DDS Private Practice Limited to Periodontics Orthodontics and Implant Dentistry Specialized Dentistry of New York New York City, New York Clinical Associate Professor New York University College of Dentistry New York City, New York Clinical Consultant Milestone Scientific, Inc Livingston, New Jersey vii www.pdflobby.com This page intentionally left blank ... Preface The sixth edition of Handbook of Local Anesthesia! As happened with previous editions, I truly find it hard to comprehend how many years have transpired since the 1st edition was published... were developed as a result of his research into computer delivery of local anesthetics A DVD accompanied the fifth edition of Local Anesthesia It followed the structure of the textbook, providing... concentration of local anesthetic, a fact that may explain the clinical situation of inadequate pulpal anesthesia developing in the presence of subjective symptoms of adequate soft tissue anesthesia