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CLASSIFICATIONOF VACINES FOUR MAIN TYPES OF VACINE Live Attenuated Vaccines(LAV) Inactivated (Killed) Vaccines Toxoid Vaccine 4.Subunit vaccines 1 LIVE ATTENUATED VACCINES(LAV) LAVs are are derived from diseasecausing pathogens(virus or bacteria) that have been weakened under laboratory conditions Examples are Measles, Mumps, Rubella, Smallpox, Chickenpox,… INACTIVATED (KILLED) VACCINES Inactivated vaccines are made from microorganisms (viruses, bacteria, other) that have been killed through physical or chemical processes Examples are Influenza, Cholera, Polio, Hepatitis A and Rabies TOXOID VACCINE Toxoid Vaccines are based on the toxin produced by certain bacteria (e.g tetanus or diphtheria) The immune process produces antibodies that lock onto and block the toxin when the vaccines are administered 4.SUBUNIT VACCINES Like inactivated vaccines, not contain live components of the pathogen They differ from inactivated vaccines by containing only the antigenic parts of the pathogen These parts are necessary to elicit a protective immune response CLASSIFICATION OF SUBUNIT VACCINES Subunit vaccines can be further categorized into: Protein based subunit vaccines (e.g: pertussis(aP)vaccines,Hepatitis B vaccines.) Polysaccharide vaccines (e.g: Meningococcal disease, Pneumococcal disease.) Conjugate subunit vaccines (e.g: Haemophilus influenzae type b (Hib).) ... components of the pathogen They differ from inactivated vaccines by containing only the antigenic parts of the pathogen These parts are necessary to elicit a protective immune response CLASSIFICATION. ..FOUR MAIN TYPES OF VACINE Live Attenuated Vaccines(LAV) Inactivated (Killed) Vaccines Toxoid Vaccine 4.Subunit... of the pathogen These parts are necessary to elicit a protective immune response CLASSIFICATION OF SUBUNIT VACCINES Subunit vaccines can be further categorized into: Protein based subunit vaccines