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Improving the diagnosis and treatment of smear-negative pulmonary and extrapulmonary tuberculosis among adults and adolescents Recommendations for HIV-prevalent and resource-constrained settings Improving the diagnosis and treatment of smear-negative pulmonary and extrapulmonary tuberculosis among adults and adolescents Recommendations for HIV-prevalent and resource-constrained settings STOP TB DEPARTMENT DEPARTMENT OF HIV/AIDS © World Health Organization 2006 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: permissions@who.int). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publica- tion. However, the published material is being distributed without warranty of any kind, either expressed or implied. The respon- sibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. The named authors alone are responsible for the views expressed in this publication. Contents Acknowledgements iv Abbreviations v Part I. Improving the diagnosis and treatment of smear-negative tuberculosis 1 Background 3 Target audience 3 Process of formulation 3 Strength of the recommendations 4 Implementation and evaluation 4 Recommendations 5 Algorithms for the diagnosis of smear-negative tuberculosis 8 Part II. Simplified and standardized clinical management guidelines for extrapulmonary tuberculosis 15 Background 17 Target audience 17 Diagnosis and management 17 Further reading 23 References 24 Annex. Protocol for operational evaluation of the revised recommendations and algorithms for improving the diagnosis of tuberculosis in HIV-prevalent settings 27 Background 29 Objectives of the evaluation 29 Purpose of the protocol 29 Hypotheses 30 Study design and procedure 30 References 36 iii Prepared by Members of the WHO Expert Group on Smear- Negative TB: Getachew Aderaye (Addis Ababa University, Ethiopia), Ludwig Apers (Institute of Tropical Medicine, Antwerp, Belgium), Leopold Blanc (World Health Organization, M I N D S & H E A R T S: A Specialist Clinic for Autism Spectrum Conditions Autism Spectrum Conditions: Diagnosis and Treatment, Advanced Workshop – Melbourne, VIC, Australia Thursday 25th & Friday 26th July 2013, 9.00am – 4.30pm Presented by: Professor Tony Attwood & Dr Michelle Garnett Professor Tony Attwood is a world expert and leading authority on Asperger’s Syndrome (AS) and autism Tony is a clinical psychologist who has specialised in autism spectrum conditions since he qualified as a clinical psychologist in England in 1975 His book “Asperger's Syndrome – A Guide for Parents and Professionals” has sold over 350,000 copies and has been translated into over twenty languages He has worked with over 6,000 individuals of all ages with Asperger's syndrome or an Autism Spectrum Condition His latest book “The Complete Guide to Asperger's Syndrome” was published in October 2006 Dr Michelle Garnett is the Founder of Minds & Hearts, a specialist clinic in Brisbane for children and adults who have an autism spectrum condition (ASC) Both are internationally known presenters, having presented together around Australia, New Zealand and Europe for numerous Universities, Societies, Colleges, Schools and Support Networks Tony and Michelle are clinical psychologists who together have over 50 years of experience in helping people with autism spectrum conditions They are warm, inspiring engaging and knowledgeable presenters Event endorsed for workshop requirement for entry to the APS/Medicare Autism and Pervasive Developmental Disorders (PDD) Identified Practitioners List The purpose of the Advanced Workshop is to develop participants’ skills in assessing more difficult and complex presentations of ASC, and for treating adolescents, adults, couples and families affected by ASC Each presenter has extensive clinical experience in ASC, and draws from this experience to provide both case presentations and simulations to strengthen each participant’s learning Time is provided for questions and discussion This workshop will follow on from the Basic Workshop and participants may decide themselves whether to register without attending the Basic Workshop Basic knowledge and some experience with ASC are assumed VENUE: Rydges on Swanston, 701 Swanston Street, Carlton, VIC REGISTER ONLINE: www.mindsandhearts.net or TELEPHONE: (07) 3844 9466 or Complete the Registration Form below Most of the books and resources described in our seminars are available from Resources at Hand book store www.resourcesathand.com.au REGISTRATION FORM – ASC: WORKSHOP OR ADVANCED WORKSHOP or BOTH – MELBOURNE 2013 TAX INVOICE ABN: 51 128 736 103 Please complete form and send to Minds & Hearts, P O Box 5675, West End QLD, 4101, OR Fax 07 3844 9533 Payment can be made via Credit Card (except Diners Club & Amex), Cheque or Money Order Please make cheques or money orders payable to Minds & Hearts Name(s): _ Address: _ Phone: Mobile: _ Email: _ I WOULD LIKE TO ATTEND: (Please circle) ASC: WORKSHOP OR th ASC: ADVANCED WORKSHOP OR BOTH th Basic Workshop - Thurs 14 & Fri 15 March 2013 Advanced Workshop – Thurs 25th & Fri 26th July 2013 9.00am to 4.30pm Rydges on Swanston, 701 Swanston Street, Carlton, VIC One Workshop Both Workshops Regular th Early Bird (before 15 February for Basic Workshop only or both th workshops; before 25 June for Advanced Workshop only) $660 $1210 $630 $1100 Full time Student $590 $1010 If you are a full-time student requiring a discount please also send in a photocopy of your Student ID Card For cancellations: Up to 14 days notice payment will be refunded, minus a $50 administrative fee At less than days notice there will be a refund of 50% of the fee Attendance is fully transferable PAYMENT METHOD (Please circle): CHEQUE MONEY ORDER AMOUNT: $ _ CREDIT CARD CREDIT CARD DETAILS: Name on Card: MASTERCARD VISA BANKCARD Credit Card Number: _ _ Expiry Date: / _ Signature: Receipts will be posted or emailed out and attendance certificates will be mailed on request OSTEOARTHRITIS – DIAGNOSIS, TREATMENT AND SURGERY Edited by Qian Chen Osteoarthritis – Diagnosis, Treatment and Surgery Edited by Qian Chen Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Vana Persen Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Osteoarthritis – Diagnosis, Treatment and Surgery, Edited by Qian Chen p. cm. 978-953-51-0168-0 Contents Preface IX Part 1 General Treatment of OA 1 Chapter 1 Long-Term Treatment of Osteoarthritis Pain: Achieving a Balance Between Efficacy and Tolerability for a Successful Chronic Therapy 3 Mila Etropolski Chapter 2 Characterization of Live and Experimentally Degenerated Hyaline Cartilage with Thermal Analysis 27 Gellért Sohár, Piroska Szabó-Révész, Kálmán Tóth and Zoltán Aigner Chapter 3 Topical and Regional Treatment for Osteoarthritis 47 Leena Patel and Charles Mackworth-Young Chapter 4 Intra-Articular Injections for the Treatment of Osteoarthritis: Focus on the Clinical Use of Several Regimens 67 Dong Rak Kwon and Gi Young Park Chapter 5 Hyaluronic Acid in the Treatment of Osteoarthritis: What is New 101 Michele Abate and Vincenzo Salini Chapter 6 Gene Therapy for Human Osteoarthritis 123 Magali Cucchiarini and Henning Madry Part 2 Alternative Treatment of OA 141 Chapter 7 Peloidotherapy in Osteoarthritis-Modulation of Oxidative Stress 143 Viorica Marin, Olga Surdu, Daniela Profir and Sibel Demirgian Chapter 8 Ginger and Osteoarthritis 157 Tessa Therkleson VI Contents Part 3 OA in Upper Extremity (Hand, Wrist, Shoulder, and Elbow) 169 Chapter 9 Osteoarthritis of the Wrist 171 Nimit Patel, Glenn Russo and Craig Rodner Chapter 10 Osteoarthritis of the Trapeziometacarpal Joint (TMJ): A Review of the Literature 203 Oliver Boughton and Hugh Mackenzie Chapter 11 Low Level Laser Therapy in the Treatment of Temporomandibular Joint Arthritis: Questions and Answers 211 Marini Ida OSTEOARTHRITIS – DIAGNOSIS, TREATMENT AND SURGERY Edited by Qian Chen Osteoarthritis – Diagnosis, Treatment and Surgery Edited by Qian Chen Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Vana Persen Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Osteoarthritis – Diagnosis, Treatment and Surgery, Edited by Qian Chen p. cm. 978-953-51-0168-0 Contents Preface IX Part 1 General Treatment of OA 1 Chapter 1 Long-Term Treatment of Osteoarthritis Pain: Achieving a Balance Between Efficacy and Tolerability for a Successful Chronic Therapy 3 Mila Etropolski Chapter 2 Characterization of Live and Experimentally Degenerated Hyaline Cartilage with Thermal Analysis 27 Gellért Sohár, Piroska Szabó-Révész, Kálmán Tóth and Zoltán Aigner Chapter 3 Topical and Regional Treatment for Osteoarthritis 47 Leena Patel and Charles Mackworth-Young Chapter 4 Intra-Articular Injections for the Treatment of Osteoarthritis: Focus on the Clinical Use of Several Regimens 67 Dong Rak Kwon and Gi Young Park Chapter 5 Hyaluronic Acid in the Treatment of Osteoarthritis: What is New 101 Michele Abate and Vincenzo Salini Chapter 6 Gene Therapy for Human Osteoarthritis 123 Magali Cucchiarini and Henning Madry Part 2 Alternative Treatment of OA 141 Chapter 7 Peloidotherapy in Osteoarthritis-Modulation of Oxidative Stress 143 Viorica Marin, Olga Surdu, Daniela Profir and Sibel Demirgian Chapter 8 Ginger and Osteoarthritis 157 Tessa Therkleson VI Contents Part 3 OA in Upper Extremity (Hand, Wrist, Shoulder, and Elbow) 169 Chapter 9 Osteoarthritis of the Wrist 171 Nimit Patel, Glenn Russo and Craig Rodner Chapter 10 Osteoarthritis of the Trapeziometacarpal Joint (TMJ): A Review of the Literature 203 Oliver Boughton and Hugh Mackenzie Chapter 11 Low Level Laser Therapy in the Treatment of Temporomandibular Joint Arthritis: Questions and Answers 211 Marini Ida and Gatto Maria Rosaria Part 4 Diagnosis MESOTHELIOMAS – SYNONYMS AND DEFINITION, EPIDEMIOLOGY, ETIOLOGY, PATHOGENESIS, CYTO-HISTOPATHOLOGICAL FEATURES, CLINIC, DIAGNOSIS, TREATMENT, PROGNOSIS Edited by Alexander Zubritsky Mesotheliomas – Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto-Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis Edited by Alexander Zubritsky Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2011 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Oliver Kurelic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published January, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Mesotheliomas – Synonyms and Definition, Epidemiology, Etiology, Pathogenesis, Cyto- Histopathological Features, Clinic, Diagnosis, Treatment, Prognosis, Edited by Alexander Zubritsky p. cm. ISBN 978-953-307-845-8 free online editions of InTech Books and Journals can be found at www.intechopen.com Contents Preface IX Chapter 1 Molecular Pathogenesis of Malignant Pleural Mesothelioma 1 Philip A. Rascoe, Xiaobo X. Cao and W. Roy Smythe Chapter 2 Stem Cells and Mesothelioma 17 Bonnie W. Lau Chapter 3 Radiologic Evaluation of Malignant Pleural and Peritoneal Mesothelioma 27 Elif Aktas, Kemal Arda, Bora Aktas, Sahin Coban, Nazan Çiledağ and Bilgin Kadri Aribas Chapter 4 Primary Malignant Pericardial Mesothelioma 39 Jesus Montesinos, Sílvia Catot, Francesc Sant and Montserrat Domenech Chapter 5 Testicular Mesothelioma 49 Alexander N. Zubritsky Chapter 6 Para- and Intratesticular Aspects of Malignant Mesothelioma 71 Zachary Klaassen, Kristopher R. Carlson, Jeffrey R. Lee, Sravan Kuvari and Martha K. Terris Chapter 7 Mesothelioma in Domestic Animals: Cytological and Anatomopathological Aspects 87 Winnie A. Merlo and Adriana S. Rosciani Chapter 8 Immuno-Oncology and Immunotherapy 97 R. Cornelissen, J.G.J.V. Aerts and J.P.J.J. Hegmans Chapter 9 The Role of Immunotherapy in the Treatment of Mesothelioma 121 Saly Al-Taei, Jason F. Lester and Zsuzsanna Tabi VI Contents Chapter 10 Connexin 43 New edition 2009 DENGUE GUIDELINES FOR DIAGNOSIS, TREATMENT, PREVENTION AND CONTROL TREATMENT, PREVENTION AND CONTROLTREATMENT, PREVENTION AND CONTROL DENGUE GUIDELINES FOR DIAGNOSIS, TREATMENT, PREVENTION AND CONTROL New edition Neglected Tropical Diseases (NTD) TDR/World Health Organization HIV/AIDS, Tuberculosis and Malaria (HTM) 20, Avenue Appia World Health Organization 1211 Geneva 27 Avenue Appia 20, 1211 Geneva 27, Switzerland Switzerland Fax: +41 22 791 48 69 Fax: +41 22 791 48 54 www.who.int/neglected_diseases/en www.who.int/tdr neglected.diseases@who.int tdr@who.int New edition 2009 DENGUE GUIDELINES FOR DIAGNOSIS, TREATMENT, PREVENTION AND CONTROL GUIDELINES FOR DIAGNOSIS, TREATMENT, PREVENTION AND CONTROL A joint publication of the World Health Organization (WHO) and the Special Programme for Research and Training in Tropical Diseases (TDR) WHO/HTM/NTD/DEN/2009.1 Expiry date: 2014 © World Health Organization 2009 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: bookorders@who.int). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: permissions@who.int). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. All reasonable precautions have been taken by the World Health Organization to verify the information contained in this publication. However, the published material is being distributed without warranty of any kind, either expressed or implied. The responsibility for the interpretation and use of the material lies with the reader. In no event shall the World Health Organization be liable for damages arising from its use. Printed in France Cover and Layout: P. Tissot WHO/HTM/NTD WHO Library Cataloguing-in-Publication Data Dengue: guidelines for diagnosis, treatment, prevention and control New edition. 1.Dengue - diagnosis. 2.Dengue - therapy. 3.Dengue - prevention and control. 4.Endemic Diseases - prevention and control. 5.Fluid therapy. 6.Diagnosis, differential. 7.Disease outbreaks - prevention and control. 8.Mosquito control. 9.Guidelines. I.World Health Organization. ISBN 978 92 4 154787 1 (NLM classification: WC 528) iii Introduction, Methodology, Acknowledgements, Abbreviations, Preface CONTENTS Preface v Methodology vi Acknowledgements vii Abbreviations ix Chapter 1 Epidemiology, burden of disease and transmission 1.1 Dengue epidemiology 3 1.2 Burden of disease 12 1.3 Dengue in international travel 13 1.4 Transmission 14 1.5 References 17 Chapter 2 Clinical management and delivery of clinical services 2.1 Overview 25 2.2 Delivery of clinical services and case management 29 2.3 Recommendations for treatment 32 2.4 References 54 Chapter 3 Vector management and delivery of vector control services 3.1 Overview 59 3.2 Methods of vector control 60 3.3 Delivery of vector control interventions 72 3.4 References 86 Chapter 4 Laboratory diagnosis and diagnostic tests 4.1 Overview 91 4.2 Considerations in the choice of diagnostic methods 93 .. .REGISTRATION FORM – ASC: WORKSHOP OR ADVANCED WORKSHOP or BOTH – MELBOURNE 2013 TAX INVOICE ABN: 51 128 736 103 Please complete form and send to Minds & Hearts, P... _ I WOULD LIKE TO ATTEND: (Please circle) ASC: WORKSHOP OR th ASC: ADVANCED WORKSHOP OR BOTH th Basic Workshop - Thurs 14 & Fri 15 March 2013 Advanced Workshop – Thurs 25th & Fri 26th July 2013... Street, Carlton, VIC One Workshop Both Workshops Regular th Early Bird (before 15 February for Basic Workshop only or both th workshops; before 25 June for Advanced Workshop only) $660 $1210

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