Vietnam market overview 2q2014 USD

BAYER H/C BIDIPHAR TRAPHACO FRESENIUS BIDIPHAR DOMESCO J&J STADA BAXTER ST.PAUL BRANDS HOSPIRA Million US$ MAT SPLY QTR % ±% EI V/Increase UNIT ±% mill US$ mill Unit UNIT... IPSEN GS

VIETNAM MARKET OVERVIEW

2Q - 2014

Therapy Classes Level 1 Performance

3

Survey Market: US$ 2,432 mill (+5%)

J - SYSTEMIC INFECTIVES (G:-3%

ANTI-EI: 92) 20.9%

A - ALIMENTARY T.&

METABOLISM (G:3%

EI: 99) 19.5%

C - CARDIOVASCULAR SYSTEM (G:5% EI:

101) 11.2%

L - ANTINEOPLAST+IMMU NOMODUL (G:14% EI:

109) 6.8%

N - NERVOUS SYSTEM (G:6% EI: 101) 6.6%

R - RESPIRATORY SYSTEM (G:14% EI:

109) 6.0%

M - SKELETAL SYSTEM (G:10% EI: 105) 5.5%

MUSCULO-K - HOSPITAL SOLUTIONS (G:5% EI:

101) 4.5%

V - VARIOUS (G:6%

EI: 102) 4.1%

G - G.U.SYSTEM & SEX HORMONES (G:4% EI:

100)

DERMATOLOGICALS (G:13% EI: 108) 3.6%

B - BLOOD + B.FORMING ORGANS (G:1% EI: 97) 3.4%

S - SENSORY ORGANS (G:23% EI: 117) 2.1%

H - SYSTEMIC HORMONES (G:5% EI:

101) 1.4%

T - DIAGNOSTIC AGENTS (G:9% EI:

104) 0.6%

P - PARASITOLOGY (G:2% EI: 97) 0.2%

MAT

2Q 14

ALL OTHER (G:4%;

E:100) 39.8%

HCMC (G:1%; E:96) 31.9%

DA NANG (G:14%;

E:109) 2.9%

Regions Performance

5

Pharmacy Survey Market: US$ 886 mill (+8%)

Hospital Survey Market: US$ 1,546 mill (+3%)

MAT

2Q 14

ALL OTHER (G:10%;

E:102)34.4%

HCMC (G:4%; E:96)30.3%

HANOI (G:5%; E:98)19.3%

CAN THO (G:12%;

E:104)6.4%

DA NANG (G:21%;

E:112)5.3%

HAI PHONG (G:12%;

E:104)

(G:2%; E:99)42.9%

HCMC 1%; E:97)32.8%

(G:-HANOI (G:11%;

E:108)18.7%

CAN THO (G:4%; E:101)2.5%

HAI PHONG (G:16%; E:113)1.6%

DA NANG (G:3%; E:100)1.5%

Survey Market Trend

670

W eig h ted A vg P rice

V alu e M illion U S $

P ack M illion

54.7 52.9 50.5 46.2 44.7 37.3 32.9 31.2 30.8 29.6 29.4 29.1 29.0 27.9 25.2 23.6 23.4

0.00

0.35 0.13 1.12

0.00 0.02 0.29 0.06 0.19

0.00 0.05

0.00

0.03 0.00

SANOFI GSK NOVARTIS DHG PHARMA ASTRAZENECA ROCHE MSD PFIZER SERVIER BOEH INGEL.

BAYER H/C BIDIPHAR TRAPHACO FRESENIUS BIDIPHAR

DOMESCO J&J STADA BAXTER ST.PAUL BRANDS HOSPIRA

Million US$

MAT SPLY QTR % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

31.5 28.7 23.7 23.6 13.7

13.5 13.1 12.4 12.4 11.9 11.9 11.7 10.5 10.0 9.6 9.2 8.7 8.7 8.4 8.3

0.00

0.02

0.00 0.00 0.00

0.00 0.03 0.00 0.00

SANOFI TRAPHACO DHG PHARMA ST.PAUL BRANDS BOEH INGEL.

IPSEN GSK HOA THIEN PHU MEGA LIFESCIENCES

TU VAN YD Q/TE-IMC

OPC (TW26) UNITED PHARMA

J&J MSD BMS NOVARTIS NHAT NHAT NAM DUOC PHARMEDIC BIDIPHAR

MAT SPLY QTR Million US$ % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

67.1 53.3

52.3 49.5 45.9 44.7 36.2 32.5 30.9 26.3 25.8 25.5 25.2 23.4 23.0 22.5 19.6 19.2 18.5 18.2

0

0

0.02 0

0.06 0.1 0.35 0.29

0.13 1.1 0.02

0 0

GSK SANOFI ASTRAZENECA ROCHE NOVARTIS PFIZER MSD SERVIER DHG PHARMA FRESENIUS BIDIPHAR

BAYER H/C DOMESCO BAXTER HOSPIRA STADA BIDIPHAR MERCK SERONO BOEH INGEL.

J&J PYMEPHARCO >>

MAT SPLY QTR Million US$ % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

51.5 39.1

26.4 23.0 22.8 20.6 20.0 19.6 19.2 15.4 13.8 13.3 13.2 12.5 12.3 12.2 11.6 11.3 11.1 10.1

0

0 0 0.02 0.02 0

0 0.18 0.06 0.1

0.54 0.13

0 0

SANOFI GSK DHG PHARMA NOVARTIS ST.PAUL BRANDS

MSD PFIZER BOEH INGEL.

SERVIER STADA BAYER H/C ASTRAZENECA

J&J TRAPHACO HOA THIEN PHU MEGA LIFESCIENCES

TU VAN YD Q/TE-IMC MERCK SERONO UNITED PHARMA

MAT SPLY QTR Million US$ % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

43.7 41.1 39.7 33.3 32.1 28.8 28.3 25.8 25.6 24.7 24.3 23.3 20.4 18.3 18.1 17.4 17.1 16.6 16.5 15.8

0.03

0

0 0 0 0

0.25 0.58

0 0 0

0.03

ROCHE GSK ASTRAZENECA SANOFI NOVARTIS BIDIPHAR DHG PHARMA FRESENIUS BIDIPHAR

MSD PFIZER BAXTER HOSPIRA DOMESCO PYMEPHARCO >>

SERVIER BAYER H/C TRAPHACO B.BRAUN PHARBACO (TW1)

MAT SPLY QTR Million US$ % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

2Q 14 MAT

OTC Vs Ethical

84.85 80.25 55.12 54.68 52.94 50.51 46.18 44.69 37.34 32.89 31.20 30.80 29.58 29.35 29.14 28.98 27.86 25.17 23.59 23.36

524 2,573 818 685 724 5,797 22,246 3,116 901 3,877 1,303 13,195 3,821 5,648 3,121 1,399 12,675 5,179 36,171 18,816

OTHER IMAGING AGENTS - T01X DPP-IV INHIBITOR A-DIABS - A10N

VITAMIN K ANTAGONISTS - B01A SPEC ANTIRHEUMATIC AGENT - M01C

LIP.REG.CO.W.OTH.LIP.REG - C10C

BLOOD COAGULATION - B02D PROTEIN KINASE INH A-NEO - L01H

IRON-CHELATING AGENTS - V03F ANTI-TNF PRODUCTS - L04B ANTI-ALZHEIMER PRODUCTS - N07D

OTH N-STER INFLAM SKIN - D05X FAT EMULSIONS,INCL TPN - K01D HAEMO DIALYSIS SOLUTIONS - K06A

OTHER METABOLIC PRODUCTS - A16A

PROTEIN SUPPLEMENTS - V06B TOP ANTIPSORIASIS PRDS - D05A

ANGIOTEN-II ANTAG, COMB - C09D

Corporation Leading Share in

TC3s Product Leading Share in TC3s

MSD 46.0% JANUVIA - MSD 26.3%

ECO >> 77.8% COUMADINE E10>> - ECO >> 42.4%

FORIPHARM (TW3) 38.3% LUMBROTINE - FORIPHARM (TW3) 38.3%

FRESENIUS BIDIPHAR 29.5% KABIVEN PERIPHERAL - FRESENIUS BIDIPHAR 11.0%

FRESENIUS BIDIPHAR 46.7% KETOSTERIL - FRESENIUS BIDIPHAR 46.7%

PT SOHO INDUSTRI 21.9% AMINORAL - PT SOHO INDUSTRI 21.9%

LEO 81.7% DAIVOBET - LEO 31.8%

PSYCHOTROPICS 25.3% TELPIL H - PSYCHOTROPICS 25.3%

BOEH INGEL 100.0% BERODUAL - BOEH INGEL 51.4%

HOA THIEN PHU 24.1% SAC NGOC KHANG - HOA THIEN PHU 21.2%

Slide auto layout FOR REFERENCE ONLY

Cut-off size: US$ 500,000

Top 10 Fastest Growing Therapy Classes Level III

CEPHALOSPORINS & COMBS - J01D

ANTIULCERANTS - A02B BROAD SPECTRUM PENICILLIN - J01C NON-NARCOTIC ANALGESICS - N02B OTH MUSCULO-SKELETAL PRDS - M05X

CEREB.+PERIPHE.VASOTHERAP - C04A HEPAT PROTECT-LIPOTROPICS - A05B OTH B-LACTAM EX PEN,CEPH - J01P ALL OTH.THERAPEUTIC PRDS - V03X FLUOROQUINOLONES - J01G ANTIRHEUMATIC NON-STEROID - M01A

OTHER DERMATOLOGICALS - D11A CHOLEST&TRIGLY.REGULATOR - C10A

CALCIUM - A12A VINCA ALKALOIDS - L01C MACROLIDES & SIMILAR TYPE - J01F PROTEIN SOLUTIONS - K03B

TONICS - A13A ANTI-INFLAMMATORY ENZYME - V03H

NOOTROPICS - N06D

71.0 56.1 56.0 51.9 51.8 46.7 42.1 39.0 37.8 36.2 34.9 34.5 33.2 31.1 29.5 29.4 27.8

78.9

221.9

25.4

Corporation Leading Share in

TC3s Product Leading Share in TC3s

GSK 26.8% AUGMENTIN - GSK 24.7%

BMS 17.9% EFFERALGAN - BMS 10.9%

ST.PAUL BRANDS 14.9% JEX - ST.PAUL BRANDS 14.8%

TRAPHACO 14.6% HOAT HUYET D/NAO - TRAPHACO 10.8%

MSD 28.3% TIENAM - MSD 23.5%

JSC SCIENTIFIC 5.8% REAMBERIN - JSC SCIENTIFIC 5.8%

HOA THIEN PHU 24.1% SAC NGOC KHANG - HOA THIEN PHU 21.2%

ST.PAUL BRANDS 16.7% ALIPAS - ST.PAUL BRANDS 16.7%

ITALFARMACO 22.3% GLIATILIN - ITALFARMACO 22.3%

Slide auto layout FOR REFERENCE ONLY

17.55 13.17

10.97 10.97 10.54 9.60 9.28 8.90 8.53 8.32 8.30 8.28 8.19 8.06 7.76 7.67 7.62 7.57 6.55 6.33

AUGMENTIN - GSK ZINNAT - GSK MERONEM - ASTRAZENECA

TIENAM - MSD DIANEAL LOW CALCI - BAXTER DIAMICRON - SERVIER NEXIUM - ASTRAZENECA CEREBROLYSIN - EVER NEURO PHARMA

TARCEVA - ROCHE MIXTARD 30 - NOVO NORDISK A/S

JEX - ST.PAUL BRANDS COVERSYL - SERVIER ALPHACHYMOTRYPSIN - SANOFI CALCIUM CORBIERE - SANOFI HUMAN ALBUMIN - BAXTER SAC NGOC KHANG - HOA THIEN PHU

PLAVIX - SANOFI ANZATAX - HOSPIRA HAGINAT - DHG PHARMA BISEKO - BIOTEST PHARMA

MAT SPLY QTR % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

8.30 8.06 7.67 6.12 6.09 6.01 5.83 5.70 5.58 5.20 4.91 4.84 4.79 4.53 4.50 4.44 4.29 3.97 3.57 3.52

JEX - ST.PAUL BRANDS CALCIUM CORBIERE - SANOFI SAC NGOC KHANG - HOA THIEN PHU

EFFERALGAN - BMS BOGANIC - TRAPHACO TANAKAN - IPSEN HOAT HUYET NHATNHA - NHAT NHAT

ENTEROGERMINA - SANOFI HOAT HUYET D/NAO - TRAPHACO ANGELA WOMENS GINS - ST.PAUL BRANDS

ALIPAS - ST.PAUL BRANDS

MARVELON - MSD HAPACOL - DHG PHARMA PHARMATON - BOEH INGEL.

DAFLON - SERVIER PANADOL EXTRA - GSK PROSPAN - ENGELHARD ARZNEIMI

SALONPAS - HISAMITSU STREPSILS - RECKITT BENCKISER PHOSPHALUGEL - BOEH INGEL.

17.55 13.17

10.97 10.97 10.54 9.60 9.28 8.90 8.53 8.32 8.28 8.19 7.76 7.62 7.57 6.55 6.33 6.26 6.25 6.01

AUGMENTIN - GSK ZINNAT - GSK MERONEM - ASTRAZENECA

TIENAM - MSD DIANEAL LOW CALCI - BAXTER DIAMICRON - SERVIER NEXIUM - ASTRAZENECA CEREBROLYSIN - EVER NEURO PHARMA

TARCEVA - ROCHE MIXTARD 30 - NOVO NORDISK A/S

COVERSYL - SERVIER ALPHACHYMOTRYPSIN - SANOFI HUMAN ALBUMIN - BAXTER

PLAVIX - SANOFI ANZATAX - HOSPIRA HAGINAT - DHG PHARMA BISEKO - BIOTEST PHARMA CONCOR - MERCK SERONO DBL OXALIPLATIN - HOSPIRA CIPROBAY - BAYER H/C

7.61 7.18 7.18 6.54 5.35 5.16 5.03 4.83 4.74 4.72 4.65 4.45 4.37 4.23 4.00 3.73 3.69 3.63

AUGMENTIN - GSK JEX - ST.PAUL BRANDS SAC NGOC KHANG - HOA THIEN PHU

ZINNAT - GSK CALCIUM CORBIERE - SANOFI ALPHACHYMOTRYPSIN - SANOFI HOAT HUYET NHATNHA - NHAT NHAT

EFFERALGAN - BMS ANGELA WOMENS GINS - ST.PAUL BRANDS

TANAKAN - IPSEN ALIPAS - ST.PAUL BRANDS DIAMICRON - SERVIER MARVELON - MSD PHARMATON - BOEH INGEL.

ENTEROGERMINA - SANOFI PANADOL EXTRA - GSK GLUCOPHAGE - MERCK SERONO HOAT HUYET D/NAO - TRAPHACO

SALONPAS - HISAMITSU CEREBROLYSIN - EVER NEURO PHARMA

Slide auto layout FOR REFERENCE ONLY

7.57 7.24 7.14 6.77 6.59 6.29 6.24 5.99 5.79 5.74 5.49 5.32 5.30 5.27 5.27

10.88

5.25

MERONEM - ASTRAZENECA

TIENAM - MSD DIANEAL LOW CALCI - BAXTER

TARCEVA - ROCHE ANZATAX - HOSPIRA AUGMENTIN - GSK HUMAN ALBUMIN - BAXTER NEXIUM - ASTRAZENECA MIXTARD 30 - NOVO NORDISK A/S BISEKO - BIOTEST PHARMA DBL OXALIPLATIN - HOSPIRA

ZINNAT - GSK MABTHERA - ROCHE HUMAN ALBUMIN - HUMAN BIOPLAZMA

SEVORANE - ABBVIE HAGINAT - DHG PHARMA GLIATILIN - ITALFARMACO NANOKINE - NANOGEN PHARMA CEREBROLYSIN - EVER NEURO PHARMA

INFANRIX HEXA - GSK

Slide auto layout FOR REFERENCE ONLY

Million US$

MAT SPLY QTR % ±% EI V/Increase UNIT ±%

(mill US$) (mill Unit) UNIT

New Products

27

Size: US$ 72.9 mill & Share: 3.0%

New Form0.6% - US$

14.3 mill

New brands 2.4% - US$

58.4 mill

Definition of New Products:

• Available in the market

• Within 1 year (since 2Q2013)

MAT

2Q 14

J - SYSTEMIC INFECTIVES 20.7%

ANTI-L - ANTINEOPLAST+IMMUNOM

ODUL 10.7%

C - CARDIOVASCULAR SYSTEM 9.9%

M - MUSCULO-SKELETAL

SYSTEM 6.3%

V - VARIOUS 6.2%

G - G.U.SYSTEM & SEX HORMONES 5.7%

N - NERVOUS SYSTEM

4.2% B - BLOOD + B.FORMING

ORGANS 4.1%

Leading product form Corporation TC4

CARMERO 1.00 G VIAL DRY IV (L ER) EUVIPHARM J01P02

BIO-ACIMIN GOLD 4 G 30 SAC GRAN (L O R) MELIPHAR-ME LINH A07F00

NEXIUM 40 MG BOX 14 MUPS TAB (I ER) ASTRAZENECA A02B02

DA HUONG MU/-TD-AL 100 ML L/SP VAG (L O R) NATA-HOA LINH G01D00

ALFALOG BOX 100 TAB F.C (IO R) RPG LIFE SCIENCES A16A00

HAEMOCTIN SDH 500 IU 10 ML VIAL DRY+SL (I ER) BIOTEST PHARMA B02D01

CEFTIZOXIME 1.00 G 10 VIAL DRY (I ER) SWISS PHARM-TAIWAN J01D02

ZIDIMBIOTIC 1000 MG 10 VIAL DRY (L ER) TENAMYD J01D02

ESSENCICAPS 300 MG BOX 50 CAPS (IO R) MINSKINTERCAPS A16A00

VIMOTRAM 1.00 G /0.5 VIAL DRY (L ER) VIET TRUNG-VCP J01C02

SUNOXIPLAT 50 MG VIAL DRY INF (I ER) SUN PHARMA L01F00

XUONG KHOP NHATNHA BOX 20 TAB F.C (L O R) NHAT NHAT M05X00

GAMMA I.V 2.5 G 50 ML INF (I ER) MEGA PRODUCT J06C00

CEFTAZIDIME (AV0) 1.00 G VIAL DRY (L ER) AMVIPHARM-AM VI J01D02

FDP MEDLAC 5 G 50 ML VIAL INF+SL (L ER) MEDLAC PHARMA C06A00

30

Slide auto layout

FOR REFERENCE ONLY

1,867 1,782 1,625 1,616 1,320

1,049 990 980 959 939 835 818 755 671 634 588 545 515 499

Leading product form Corporation TC4

BIO-ACIMIN GOLD 4 G 30 SAC GRAN (L O R) MELIPHAR-ME LINH A07F00

ALFALOG BOX 100 TAB F.C (IO R) RPG LIFE SCIENCES A16A00

HAEMOCTIN SDH 500 IU 10 ML VIAL DRY+SL (I ER) BIOTEST PHARMA B02D01

CEFTIZOXIME 1.00 G 10 VIAL DRY (I ER) SWISS PHARM-TAIWAN J01D02

ZIDIMBIOTIC 1000 MG 10 VIAL DRY (L ER) TENAMYD J01D02

ESSENCICAPS 300 MG BOX 50 CAPS (IO R) MINSKINTERCAPS A16A00

VIMOTRAM 1.00 G /0.5 VIAL DRY (L ER) VIET TRUNG-VCP J01C02

SUNOXIPLAT 50 MG VIAL DRY INF (I ER) SUN PHARMA L01F00

XUONG KHOP NHATNHA BOX 20 TAB F.C (L O R) NHAT NHAT M05X00

GAMMA I.V 2.5 G 50 ML INF (I ER) MEGA PRODUCT J06C00

CEFTAZIDIME (AV0) 1.00 G VIAL DRY (L ER) AMVIPHARM-AM VI J01D02

FDP MEDLAC 5 G 50 ML VIAL INF+SL (L ER) MEDLAC PHARMA C06A00

NEUPEG 6 MG /ML 1.00 ML SY PREF SC (I ER) INTAS L03A01

GREAXIM 1.00 G 5 ML VIAL DRY+SL (I ER) AMVIPHARM-AM VI J01D02

BAO XUAN TUOI 50 BOX 30 CAPS (L O R) NAM DUOC G02X09

31

Slide auto layout

FOR REFERENCE ONLY

1,782 1,320

1,049 990 980 959 939 835 818 755 671 634 588 545 515 499 452 451 404

Leading product form Corporation TC4

CARMERO 1.00 G VIAL DRY IV (L ER) EUVIPHARM J01P02

NEXIUM 40 MG BOX 14 MUPS TAB (I ER) ASTRAZENECA A02B02

DA HUONG MU/-TD-AL 100 ML L/SP VAG (L O R) NATA-HOA LINH G01D00

AMOXICILIN (P3B) 1000 MG BOX 100 CAPL F.C (L ER) PHARBACO (TW1) J01C01

NEXIUM 20 MG BOX 14 MUPS TAB (I ER) ASTRAZENECA A02B02

LIPIGOLD 20 % 250 ML INF BAG (I ER) JW LIFE SCIENCE K01D01

SALBUTAMOL (RDN) 5 MG /5ML 5 ML 10 AMP INF (I ER) RENAUDIN R03A02

RECTIOFAR 3 ML 50 LIQ RECTAL (L O R) PHARMEDIC A06A04

PRASOCARE 40 MG VIAL DRY IV (I ER) BHARATPARENTERALS A02B02

BIFUMAX 750 MG 8 ML VIAL DRY+SL (L ER) BIDIPHAR J01D02

PACLITAXEL STRAGEN 6 MG /ML 50 ML VIAL INF (I ER) HAUPT PHARMALIVRON L01C00

LOSARTAN STADA 25 MG BOX 30 TAB F.C (L ER) STADA C09C00

FAROMEN 1.00 G 20 ML VIAL DRY+SL (I ER) KWALITY J01P02

AUSTRIOL 250 Y BOX 100 SOFTCAP (L ER) MEBIPHAR-AUSTRAPHA A11C02

AMINOACID KABI 5 % 250 ML INFUSION (L ER) FRESENIUS BIDIPHAR K01E01

LACBIO PRO 1.00 G 30 SAC PWD (L O R) BIDIPHAR A07F00

32

Slide auto layout

FOR REFERENCE ONLY

1,625 1,616 493

489 283 255 237 194 194 192 177 171 151 145 126 126 121 115 114

Top 10 Corporations

33

Top 10 ® : Top 10 corporations with products officially

managed by Vietnam offices

SANOFI GSK

NOVARTIS DHG PHARMA ASTRAZENECA ROCHE

MSD PFIZER SERVIER BOEH INGEL.

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