[...]... E VERMETTEN, AND E.J.L GRIEZ nine out of ten responders no longer met the personality disorder criteria OCD also co-exists with a number of other axis I disorders including panic disorder (54%, Crino and Andrews, 19 96), social phobia (42%, Crino and Andrews, 19 96), eating disorders (17 %, Rasmussen and Eisen, 19 94), and Tourette’s disorder (5%, Black and Noyes, 19 90) Crino and Andrews (19 96) remark... and dermatological diseases) and anxiety disorders (especially panic disorder, GAD and agoraphobia) (Stoudemire, 19 96) In this chapter the epidemiological findings from some large population-based surveys and some smaller but relevant clinical studies will be reviewed, all DSM-IV anxiety disorders arranged by diagnostic category EPIDEMIOLOGY OF ANXIETY DISORDERS ——————————————— 5 PANIC DISORDER AND AGORAPHOBIA... previously suggested Hollander (19 97) calls OCD ‘‘the hidden epidemic’’, where social phobia has been called ‘‘the neglected anxiety disorder’’ (Liebowitz, 19 99) An earlier cross-national study by Weissman et al (19 94), using DSM-III criteria, reports annual prevalence rates ranging from 1. 1 /10 0 in Korea and New Zealand to 1. 8 /10 0 in Puerto Rico The only exception was Taiwan (0.4 /10 0), which has the lowest... follow-up only 10 % were shown to be symptom-free (Noyes et al., 19 90) Faravelli et al (19 95) found that only 12 % of panic disorder patients after five years were in full remission Panic disorder can be a very disabling disorder with high impact on daily life and social, personal and professional functioning and can put a great strain on quality of life (Candilis and Pollack, 19 97; Candilis et al., 19 99) Comorbidity... Zebb, 19 99) EPIDEMIOLOGY OF ANXIETY DISORDERS ——————————————— 7 Natural Course Panic disorder and agoraphobia seem to be a chronic condition (Pollack and Smoller, 19 95; Hirschfeld, 19 96; Liebowitz, 19 97), mostly with a fluctuating course with periods of waxing and waning (Liebowitz, 19 97; Pollack and Otto, 19 97) In some studies longitudinal aspects have been addressed, e.g in a three-year follow-up only... B, Klein DF (19 98) Cognitive-behavioral group therapy vs phenelzine therapy for social phobia: 12 -week outcome Arch Gen Psychiatry 55 (12 ): 11 33 11 41 Hollon SD, Shelton RC, Loosen PT (19 91) Cognitive therapy and pharmacotherapy for depression J Consult Clin Psychol 59: 88–99 Klein DF (19 94) Testing the suffocation false alarm theory of panic disorder Anxiety 1: 1 7 Klein DF (19 95) Response to critique... Print ISBN 0-4 7 1- 9 789 3-6 Electronic ISBN 0-4 7 0-8 464 3-7 ———————————————————————————————— CHAPTER 1 Epidemiology of Anxiety Disorders T Overbeek, E Vermetten, and E.J.L Griez Maastricht University, Maastricht, The Netherlands INTRODUCTION Anxiety disorders have a high impact on daily life (illness intrusiveness) and cause a great deal of suffering for the individual patient (Antony et al., 19 98) They also... D Nutt and D Zohar Copyright © 20 01 John Wiley & Sons Ltd Print ISBN 0-4 7 1- 9 789 3-6 Electronic ISBN 0-4 7 0-8 464 3-7 Introduction Donald F Klein New York State Psychiatry Institute, New York Introducing an up -to- date book covering a broad range of anxiety- related topics presents a problem It seems in the nature of scientific activity that investment in one’s conclusions may lead to a less than balanced consideration... seven to nine months a prevalence of DSM-III-R PTSD of 23% Almost 50% of them had symptoms the first day, and about 70% developed PTSD symptoms during the first week after the event In one study, victims of substantiated child abuse and neglect were assessed and compared with a group of matched non-abused and non-neglected children and followed into adulthood Victims of child abuse (sexual and physical) and. .. predisposes to panic disorder in later life (Zandbergen et al., 19 91; Verburg et al., 19 95; Perna et al., 19 97) In addition, chronic obstructive pulmonary disorders can lead to panic disorder in primarily lung patients (Wingate and Hansen-Flaschen, 19 97), although the role of psychological factors, such as cognitive misinterpretation of bodily symptoms (shortness of breath) must be taken into account (Moore and . and L. Bellodi 3 Genetics of Anxiety Disorders: Part II 41 B. de Brettes and J.P. Le´pine PART II NOSOLOGY AND TREATMENT OF ANXIETY DISORDERS 51 4 Panic Disorder: Clinical Course, Morbidity and Comorbidity. disorders: an introduction to clinical management and research / edited by E.J.L. Griez . . . [et al.]. p. cm. Includes bibliographical references and index. ISBN 0-4 7 1- 9 787 3-6 (alk. paper) 1. Anxiety. . 0-4 7 0-8 464 3-7 Anxiety Disorders An Introduction to Clinical Management and Research Edited by Eric J.L. Griez Department of Psychiatry and Neuropsychology, University of Maastricht, The Netherlands Carlo