PLANTS THAT FIGHT CANCER - PART 9 ppt

80 Plumericin 268 81 Podophyllotoxin 269 82 Psoralen 269 83 Quercetin 269 84 L-Malic acid, sodium salt 270 85 Paclitaxel 270 86 Tetrahydrofuran 270 87 Thymol 271 88 Tricine 271 89 Tubulosine 271 90 S-(–)-Tyrosine 271 91 Urethane 272 92 Valtrate 272 93 Vinblastine 272 94 22-oxovincaleukoblastine 273 95 Viscotoxin A 3 273 Synonyms: 1,4-Naphthalenedione; 1,4-dihydro-1,4-diketonaphthalene; ␣-naphthoquinone. Synonyms: Accutane; 13-cis-Vitamin A acid; 13-cis-Retinoic acid; cis-retinoic acid; neovitamin A acid; 13-RA; ro-4-3780; retinoic acid, 9Z form; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)- 2,(E),4,6,8(Z,Z,Z)-nonatetraenoic acid; Isotretinoin; Accure; IsotrexGel; Roaccutane; Isotrex; Teriosal; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)2-cis-4-trans-6-trans-8-trans-nonatetraenoic acid; Tasmar. O HO Isoretinoin OO 1,4-Naphthoquinone 244 Appendix Synonyms: 4-Methoxysalicylaldehyde. Synonyms: Fluorouracil, FU; 5-FU; 5-fluoro-2,4(1H,3H)-Pyrimidinedione; Adrucil; Efudex; Fluoroplex; Ro 2-9757; Arumel; Carzonal; Effluderm (free base); Efudix; Fluoroblastin; Fluracil; Fluri; Fluril; Kecimeton; Timazin; U-8953; Ulup; 5-Fluoro-2,4-pyrimidinedione; 5-Fluoropyrimidine-2,4-dione; 5-Ftouracyl; efurix; fluracilum; ftoruracil; queroplex; 50fluoro uracil; Fluorouracil (Topical); Fluroblastin. O 5-Fluorouracil O HN N H F O O HO 22-Hydroxytingenone R 3 R 2 R 1 3 4 5 6 23 7 8 9 10 1 25 11 12 26 27 19 18 15 16 28 22 17 20 H 13 29 30 21 14 2 1HCH 3 OH R 1 R 2 R 3 O HOO H 2-H y drox y -4-methox y benzaldeh y d e Appendix 245 246 Appendix Synonyms: ADP; adenosine 5Ј-diphosphate. Synonyms: Ammonium biphosphate; Ammonium Dihydrogen Phosphate; ADP; Ammonium phosphate; Phosphoric acid, monoammonium salt; Monoammonium phosphate. O P Ammonium p hos p hate monobasic OH OH NH 4 Ј – O NH 2 N N N N O H OO O HO PP H H OHOH Adenosine diphosphate OH OH O 12 14 11 R 3 R 1 R 1 R 2 R 3 R 2 10 9 13 B O 5 6 4 16 15 1 2 N N – OMe H 9-Methox y canthin-6-one Synonyms: AFB1; AFBI aflatoxin b; 2,3,6a,9a-tetrahydro-4-methoxycyclopenta(c)furo(3Ј,2Ј:4,5)furo- (2,3-h)(1)benzopyran-1,11-dione; Aflatoxin B1, crystalline. Synonyms: AIP; 2-Propanol, aluminum salt; Aluminum(III)isopropoxide. O O O O O O OH H H H H Allamandin O O AI O Aluminum iso p ro p oxid e O O H Aflatoxin B1 O O O O H Appendix 247 Synonyms: Furo(2,3-h)coumarin. Synonyms: 5,8,11,14-icosatetraenoic acid; 5,8,11,14-Eicosatetraenoic acid, (all-Z)-; Eicosa- 5Z,8Z,11Z,14Z-tetraenoic acid. O H O Arachidonic acid O O O Angelicin O Allamcin O O O OH H H H H 248 Appendix Synonyms: all cis-Delta-5,8,11,14-icosatetraenoate. Synonyms: L-ascorbic acid; L-3-ketothreohexuronic acid; Ascorbicap; Cebid; Cecon; Cevalin; Cemill; Sunkist; L-(ϩ)-Ascorbic Acid; Acid Ascorbic; antiscorbic vitamin; antiscorbutic vitamin; cevitamic acid; 3-keto- L -gulofuranolactone; L-3-ketothreohexuronic acid lactone; laroscorbine; L-lyxoascorbic acid; 3-oxo- L-gulofuranolactone; L-xyloascorbic acid; adenex; allercorb; cantan; proscorbin; vitacin; AA; arco-cee; ascoltin; ascorb; ascorbajen; ascorbicab; ascor-b.i.d.; ascorbutina; ascorin; ascorteal; ascorvit; cantaxin; catavin c; cebicure; cebion; cee-caps td; cee-vite; cegiolan; ceglion; celaskon; ce lent; Celin; cemagyl; ce-mi-lin; cenetone; cereon; cergona; cescorbat; cetamid; cetemican; cevatine; Cevex; cevibid; cevimin; ce-vi-sol; cevital; cevitamin; cevitan; cevitex; Cewin; ciamin; Cipca; citriscorb; c-level; C-Long; colascor; concemin; C-Quin; C-Span; c-vimin; dora-c-500; davitamon c; duoscorb; L- threo-hex-2-enonic acid, ␥-lactone; Hicee; hybrin; IDO-C; lemascorb; liqui-cee; Meri-c; natrascorb injectable; 3-oxo- L-gulofuranolactone (enol form); planavit c; redoxon; ribena; roscorbic; scorbacid; scorbu-c; secorbate; testascorbic; vicelat; Vicin; vicomin c; viforcit; viscorin; vitace; vitacee; vitacimin; vitamisin; vitascorbol; Xitix; Ascorbic Acid. Synonyms: 5,6,7-Trihydroxyflavone. OH HO HO O O Baicalein O O HO Vitamin C HO HO OH HO O Arachidonic acid Appendix 249 Synonyms: 6,7-Benzopyrene; B[A]P; BP; 3,4-Benzopyrene; Benzo[d,e,f]chrysene; 3,4-Benzpyrene; Benzpyrene; 3,4-benzylpyrene; 3,4-benz[a]pyrene; 3,4-BP; Benzo[a]pyrene. Synonyms: Benzene, (isothiocyanatomethyl) Synonyms: Solatene; trans-␤-Carotene; Carotene; ␤,␤-Carotene. Synonyms: 5,7-dihydroxy-4Ј-methoxyiso-flavone;olmelin. OH HO Biochanin A O O O -Carotene N S Benzylisothiocyanate Benzo[a]pyrene 250 Appendix Appendix 251 Synonyms: 1,3,7-Trimethylxanthine; 3,7-dihydro-1,3,7-trimethyl-1H-Purine-2,6-dione; 1,3,7- Trimethyl-2,6-dioxopurine; 7-Methyltheophylline; Alert-Pep; Cafeina; Cafipel; Guaranine; Koffein; Mateina; Methyltheobromine; No-Doz; Refresh’n; Stim; Theine; 1-methyltheobromine; methyltheo- bromide; eldiatric c; organex; 1,3,7-trimethyl-2,6-dioxo-1,2,3,6-tetrahydropurine; caffenium. Synonyms: Carbachol chloride; 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-Ethanaminium chloride; Carbachol; (2-Hydroxyethyl)trimethylammonium chloride carbamate; (2-Carbamoyloxyethyl)trimethy- lammonium chloride. Synonyms: carvacrol; Phenol, 2-methyl-5-(1-methylethyl)-; Cymenol; Hydroxy-p-cymene; Isopropyl- o-cresol; Isothymol; Methyl-5-(1-methylethyl)phenol. OH 5-Isopropyl-2-methyl-phenol NЈ O Carbam y lcholine chloride Cl – H 2 N O O N N R 3 R 2 R 1 R 1 O R 2 H Canthin-6-one R 3 H 11 1 2 10 913 12 14 15 16 4 5 8 6 O Caffeine N N O N N 252 Appendix Synonyms: Cianidanol; (ϩ)-CATECHIN. Synonyms: cis-Diaminedichloroplatinum(II); cis-Platinous Diamine Dichloroplatin; CACP; CDDP; CPDD; Platinol; cis-Platinous diamine dichloride; dCDP; cis Pt II; cis-Diaminedichloroplatinum; DDP; DDPt; Platiblastin; cis-Dichlorodiamineplatinum(II); (SP-4-2)-diaminedichloroplatinum; cis- diaminodichloroplatinum(II); cis-platinum(II) diamine dichloride; cisplatyl; CPDC; cis-ddp; neoplatin; peyrone’s chloride; platinex; PT-01; diaminedichloroplatinum; cis-dichlorodiaminoplatinum(II); cis-dichlorodiamineplatinum; cis-platinous diaminodichloride; 2Ј-Deoxycytidine diphosphate; cis-Diammine dichloroplatinum(II); cis-Dichlorodiammine platinum (II); CISPLATIN (CIS- DIAMINEDICHLOROPLATIUM (II)). Synonyms: (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide; N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-acetamide; N-acetyltrimethylcolchicinic acid methyl ether; 7-acetamido-6,7-dihydro-1,2,3,10-tetramethoxy- benzo[a]heptalen-9(5H)-one; 7-␣-H-colchicine; colchineos; colchisol; colcin; colsaloid; condylon; colchiceine methyl ether; Colgout; COLCHICINE CRYSTALLINE. O O O O O O HN Colchicine NH 3 NH 3 Cl Cl Pt Cis p latin OH OH OH OH HO Catechin O Appendix 253 Synonyms: C.I. 75300; 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-; tumeric yellow; 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; C.I. natural yellow 3; curouma; diferuloylmethane; gelbwurz; Haidr; Halad; haldar; Halud; indian saffron; kachs haldi; merita earth; safra d’inde; souchet; terra merita; yellow ginger; yellow root; YO-KIN; Natural Yellow 3; E-100. Synonyms: N, N-Bis(2-Chloroethyl)tetrahydro-2H-1,3,2-Oxazaphosphorin-2-Amine, 2-Oxide; Cytoxan; Cyclophosphane; B 518; Procytox; Neosar; Cyclophosphamides; Cyclophosphoramide; Sendoxan; bis(2-Chloroethyl)phosphamide cyclic propanolamide ester; bis(2-Chloroethyl)phosphoramide cyclic propanolamide ester; N,N-bis(beta-Chloroethyl)-NЈ,O-propylenephosphoric acid ester diamide; N- bis(␤-Chloroethyl)-NЈ,O,trimethylenephosphoric acid ester diamide; Cytophosphane; 2-(bis(2- Chloroethyl)-amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; Cycloblastin; Cyclostin; (Ϫ)-Cyclophosphamide; Asta B 518; Clafen; Claphene; Cyclophosphamidum; cb 4564; Endoxan R; Endoxan-Asta; Endoxana; Endoxanal; Endoxane; Enduxan; Genoxal; Mitoxan; N,N-Bis(␤-chloroethyl)- NЈ,O-trimethylenephosphoric acid ester diamide; N,N-Bis(2-chloroethyl)-NЈ,O-propylenephosphoric acid ester diamide; N,N-Di(2-chloroethyl)-N,O-propylene-phosphoric acid ester diamide; Semdoxan; Senduxan; sk 20501; tatrahydro-2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide; 2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane 2-oxide; ASTA; N,N-bis(2- chloroethyl)-NЈ-(3-hydroxypropyl)phosphorodiamidic acid intramol. ester; tetrahydro-N,N-bis(2- chloroethyl)- 2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; 1-(bis(2-chloroethyl)amino)-1-oxo-2-aza- 5-oxaphosphoridine. Synonyms: D-(ϩ)-Galactose; Galactose; Gal; ␣-Galactose(D); D(ϩ)GALACTOSE SIGMA GRADE. O OH HO HO OH OH D-Galactose O P NH Cl Cl Cyclophosphamide O N OO Curcumin O O OH HO [...]... N-acetyl-N-methyl-, 6-ester with 11-chloro-6,21-dihydroxy-12,20-dimethoxy2,5 ,9, 16-tetramethyl-4,24-dioxa -9 , 22-diazatetracyclo[ 19. 3.1.1(10,24).0(3,5)]hexacosa10,12,14[26],16,18-pentaene-8,23-dione; N-acetyl-N-methyl-L-Alanine, [1S-(1R*,2S*,3R*,5R*, 6R*,16E,18E,20S*,21R*) ]-1 1-chloro-21-hydroxy-12,20-dimethoxy-2,5 ,9, 16-tetramethyl-8,23-dioxo4,24-dioxa -9 , 22-diazatetracyclo[ 19. 3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl... sulfate) -A 6 7 sm -T hr - L o -S e Lys - C y eIle - Viscotoxin A3 A - 36 ro - Tyr u - Thr Le P Thr - Lys - Asp - Pro 15 16 17 18 la C ys - Arg - 19 sCy Thr - Se r - G l y 46 14 -A 2 3 er 4 5 -C ys Cys - P r Leu - Lya - Ala Ser ly - 30 29 28 27 ? o - Cys - ? O Pr 26 rs - 31 41 40 32 42 25 39 43 33 38 24 34 44 37 - s e r - I l 35 45 -S a- 1 ys 13 - Tyr - Asn ie 10 11 9 ly - Arg - A 12 8 hr - G sn T -l 23... 6-amino-1,1a,2,8,8a,8b-hexahydro- 8-( hydroxymethyl )-8 a-methoxy-5-methylazirino[2Ј,3Ј:3,4]pyrrolo[1,2-a]indole-4,7-dione, carbamate (ester); (1ar )-6 -amino- 8-( ((aminocarbonyl) oxy)methyl )-1 ,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2Ј,3Ј:3,4]pyrrolo[1,2-a]indole-4,7dione O– NЈ O NH N H N N O N-methyl-NЈ-nitro-N-nitrosoguanidine Synonyms: MNNG; N-methyl-N-nitroso-NЈ-nitroguanidine; NЈ-nitro-N-nitroso-N-methylguanidine; 1-methyl-3-nitro-1-nitrosoguanidine;... methylnitronitrosoguanidine; N-nitroso-N-methylnitroguanidine; 1-methyl-1-nitroso-N-methylguanidine; 1-nitro-N-nitroso-N-methylguanidine; MNG; MethylNЈ-nitro-N-nitrosoguanidine; N-Methyl-N-Nitroso-NЈ-Nitroguanidine, 97 % - Carc Appendix 265 OH OH O HO O N H OH N-Acetylgalactosamine Synonyms: N-Acetylchondrosamine; 2-Acetamido-2-deoxygalactose; N-Acetyl-␤-D-galactosamine; N-Acetyl-D-galactosamine O N N N-Nitrosopyrrolidine... [1aR-(1a␣,8␤,8a␣,8b␣) ]-6 -amino- 8-[ [(aminocarbonyl)oxy]methyl ]-1 ,1a,2,8,8a,8b-hexahydro-8amethoxy-5-methylazirino[2Ј,3Ј:3,4]pyrrolo[1, 2- ]indole-4,7-dione; Ametycin; Mit-C; Mito-C; Mitocin-C; Mitomycinum; Mytomycin; 7-Amino -9 -methoxymitosane; Azirino[2Ј,3Ј:3,4]pyrrolo[1,2-a]indole4,7-dione, 6-amino- 8-[ [(aminocarbonyl)oxy]methyl ]-1 ,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, [1aS-(1a␣,8␤,8a␣,8b␣) ]-; 6-amino-1,1a,2,8,8a,8b-hexahydro- 8-( hydroxymethyl )-8 a-methoxy-5-methylazirino[2Ј,3Ј:3,4]pyrrolo[1,2-a]indole-4,7-dione,... 5-Hydroxy-2-methyl-1,4-naphthoquinone O O H H O H O O H O Plumericin Synonyms: [3aS-(3E,3a␣,4a␤;,7a␤,9aR*,9b␤) ]-3 -Ethylidene-3,3a,7a,9b-tetrahydro-2-oxo-2H,4aH1,4,5-trioxadicyclopent[a,hi]indene-7-carboxylic acid methyl ester Appendix 2 69 OH O O O O O O O Podophyllotoxin Synonyms: 5,8,8a , 9- Tetrahydro -9 - hydroxy- 5-( 3,4,5-trimethoxyphenyl)furo[3Ј,4Ј:6,7]naphthol[2,3-d ]-1 ,3dioxol-6(5aH)-one; 1-hydroxy-2-hydroxymethyl-6,7-methylenedioxy- 4-( 3Ј,4Ј,5Ј-trimethoxyphenyl)1,2,3,4-tetrahydronaphthalene-3-carboxylic... 6-deoxy-L-mannose; L-rhamnose; L-Mannomethylose; -6 -Deoxy-Lmannose; ␣-L-Mannomethylose; rhamnose OH OH H OH H O H HO H H H O O HO OH H H H OH H OH D-(+)-Lactose Synonyms: Milk sugar; 4-O-␤-D-galactopyranosyl-D-glucose; ␤-lactose; ␤-D-Lactose; Lactose; Lac; lactin; 4-( ␤-D-galactosido)-D-glucose; lactobiose; saccharum lactin; (ϩ )- -D-lactose O O OH Lapachol Synonyms: 2-Hydroxy- 3-( 3-methyl-2-butenyl )-1 ,4-naphthalenedione... Sinemet; [ 3-( 3,4-Dihydroxyphenyl)-L-Alanine]; L-3,4-dihydroxyphenylalanine; 3-hydroxy-L-tyrosine; L-Dihydroxyphenyl-L-alanine; 3,4-Dihydroxy-L-phenylalanine; L- -( 3,4Dihydroxyphenyl)alanine; L- 3-( 3,4-Dihydroxyphenyl)alanine OH O OH HO OH L-(+)-Arabinose Synonyms: L-Arabinopyranose; Arabinose(L); L-(ϩ)-ARABINOSE CRYSTALLINE 262 Appendix OH O OH OH OH -L-Rhamnose Synonyms: ␣-L-rhamnopyranose; 6-deoxy-L-mannose;... (2,4-Diamino-6pteridinyl)methyl)-methylamino)-benzoyl)-L-glutamic acid; cl-14377; emt 25, 299 ; Metatrexan; Methopterin; R 99 85; L-(ϩ)-amethopterin dihydrate; 4-amino-4-deoxy-N(sup 10)-methylpteroylglutamate; N-bismethylpteroylglutamic acid; N-(p-( ( (2,4-diamino-6-pteridyl)methyl)methylamino) benzoyl)glutamic acid; 4-amino-4-deoxy-N(sup 10)-methylptero ylglutamic acid; 4-aminoN(sup 10)-methylpteroylglutamic acid; methotextrate; antifolan; L-(ϩ)-N-(p-(... dodecylphenylsulfonate; AA -9 ; AA-10; abeson nam; bio-soft D-40; bio-soft D-60; bio-soft D-62; bio-soft D-35x; calsoft f -9 0 ; calsoft L-40; calsoft L-60; conco aas-35; conco aas-40; conco aas-65; conco aas90; conoco c-50; conoco c-60; conoco sd 40; detergent hd -9 0 ; mercol 25; mercol 30; naccanol nr; naccanol sw; nacconol 40f; nacconol 90 f; nacconol 35SL; neccanol sw; pilot hd -9 0 ; pilot sf-40; pilot sf-60; pilot sf -9 6 ; pilot . Appendix Synonyms: 2-Acetamido-2-deoxy-D-galactopyranose; N-Acetyl-D-chondrosamine; 2-Acetamido- 2- deoxy- D-galactose; GalNAc. Synonyms: [3aR-(3aa,5b,8ab,9aa) ]-3 a,5,6,7,8,8a ,9, 9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho- [2,3-b]furan-2(3H)-one;. (II)). Synonyms: (S)-N-(5,6,7 , 9- tetrahydro-1,2,3,10-tetramethoxy -9 - oxobenzo[a]heptalen-7-yl)acetamide; N-(5,6,7 , 9- tetrahydro-1,2,3,10-tetramethoxy -9 - oxobenzo[a]heptalen-7-yl)-acetamide; N-acetyltrimethylcolchicinic. 11-chloro-6,21-dihydroxy-12,20-dimethoxy- 2,5 ,9, 16-tetramethyl-4,24-dioxa -9 , 22-diazatetracyclo[ 19. 3.1.1(10,24).0(3,5)]hexacosa- 10,12,14[26],16,18-pentaene-8,23-dione; N-acetyl-N-methyl- L-Alanine, [1S-(1R*,2S*,3R*,5R*, 6R*,16E,18E,20S*,21R*) ]-1 1-chloro-21-hydroxy-12,20-dimethoxy-2,5 ,9, 16-tetramethyl-8,23-dioxo- 4,24-dioxa -9 , 22-diazatetracyclo[ 19. 3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl