This page intentionally left blank Carcinoma of the Esophagus Contemporary Issues in Cancer Imaging A Multidisciplinary Approach Series Editors Rodney H. Reznek Cancer Imaging, St. Bartholomew’s Hospital, London Janet E. Husband Diagnostic Radiology, Royal Marsden Hospital, Surrey Current titles in the series Cancer of the Ovary Lung Cancer Colorectal Cancer Carcinoma of the Kidney Forthcoming titles in the series Carcinoma of the Bladder Prostate Cancer Squamous Cell Cancer of the Neck Pancreatic Cancer Interventional Radiological Treatment of Liver Tumours Carcinoma of the Esophagus Edited by Sheila C. Rankin Series Editors Rodney H. Reznek Janet E. Husband CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK First published in print format ISBN-13 978-0-521-88285-9 ISBN-13 978-0-511-37745-7 © Cambridge University Press 2008 Every effort has been made in preparing this publication to provide accurate and up-to- date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors, and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors, and publishers therefore disclaimall liability for direct or consequential damages resulting fromthe use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. 2007 Information on this title: www.cambridge.org/9780521882859 This publication is in copyright. Subject to statutory exception and to the provision of relevant collective licensing agreements, no reproduction of any part may take place without the written p ermission of Cambrid g e University Press. Cambridge University Press has no responsibility for the persistence or accuracy of urls for external or third-party internet websites referred to in this publication, and does not g uarantee that any content on such websites is, or will remain, accurate or a pp ro p riate. Published in the United States of America by Cambridge University Press, New York www.cambridge.org eBook (EBL) hardback Contents Contributors vii Series foreword ix Preface to Carcinoma of the Esophagus xi 1 Epidemiology and Clinical Presentation in Esophageal Cancer Satvinder S. Mudan and Jin-Yong Kang 1 2 Pathology of Esophageal Cancer Harriet M. R. Deere 14 3 Recent Advances in the Endoscopic Diagnosis of Esophageal Cancer Anne Marie Lennon and Ian D. Penman 28 4 Endoscopic Ultrasound in Esophageal Cancer Anne Marie Lennon and Ian D. Penman 44 5 CT in Esophageal Cancer Naama R. Bogot and Leslie Eisenbud Quint 62 6 FDG-PET and PET/CT in Esophageal Cancer Sheila C. Rankin 85 7 The Role of Surgery in the Management of Esophageal Cancer and Palliation of Inoperable Disease Robert Mason 107 8 Chemotherapy and Radiotherapy in Esophageal Cancer Peter Harper and David Landau 122 v 9 Role of Stents in the Management of Esophageal Cancer Tarun Sabharwal and Andreas Adam 134 10 Lasers in Esophageal Cancer Laurence B. Lovat 145 Index 151 vi Contents Satvinder S. Mudan, BSC, MD, FRCS Consultant in Surgical Oncology Royal Marsden Hospital London, UK Ian D. Penman, MD, FRCP EDIN Consultant Gastroenterologist Lothian University Hospitals Division Western General Hospital, Edinburgh Leslie Eisenbud Quint, MD Professor of Radiology Division of Cardiothoracic Imaging University of Michigan Health System Ann Arbor, Michigan, USA Sheila C. Rankin, FRCR Consultant Radiologist Guy’s and St. Thomas’ Foundation Trust London, UK Tarun Sabharwal, FRCR, FRCSI Consultant Interventional Radiologist and Honorary Senior Lecturer Guy’s and St. Thomas’ Foundation Trust Department of Radiology St. Thomas’ Hospital London, UK viii Contributors [...]... higher incidence of SCC in low income and low socioeconomic groups [5,7,8] Adenocarcinoma The last 30 years have seen a dramatic fall in the incidence of noncardia gastric cancer and, as mentioned earlier, a decline or stabilization in the incidence of SCC of the esophagus in Western countries [9 ,10 ,11 ,12 ,13 ] Over the same period the age-standardized incidence of adenocarcinoma of the lower esophagus, previously... incidence . stabilization in the incidence of SCC of the esophagus in Western countries [9 ,10 ,11 ,12 ,13 ]. Over the same period the age-standardized incidence of adenocarcinoma of the lower esophagus, previously a. Paulo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK First published in print format ISBN -1 3 97 8-0 -5 2 1- 8 828 5-9 ISBN -1 3 97 8-0 - 51 1-3 774 5-7 © Cambridge University Press. titles in the series Cancer of the Ovary Lung Cancer Colorectal Cancer Carcinoma of the Kidney Forthcoming titles in the series Carcinoma of the Bladder Prostate Cancer Squamous Cell Cancer of the