RESEARCH Open Access Accuracy of peak VO2 assessments in career firefighters Dana C Drew-Nord 1* , Jonathan Myers 2 , Stephen R Nord 3 , Roberta K Oka 4 , OiSaeng Hong 1 and Erika S Froelicher 5 Abstract Background: Sudden cardiac death is the leading cause of on-duty death in United States firefighters. Accurately assessing cardiopulmonary capacity is critical to preventing, or reducing, cardiovascular events in this population. Methods: A total of 83 male firefighters performed Wellness-Fitness Initiative (WFI) maximal exercise treadmill tests and direct peak VO 2 assessments to volitional fatigue. Of the 83, 63 completed WFI sub-maximal exercise treadmill tests for comparison to directly measured peak VO 2 and historical estimations. Results: Maximal heart rates were overestimated by the traditional 220-age equation by about 5 beats per minute (p < .001). Peak VO 2 was overestimated by the WFI maximal exercise treadmill and the historical WFI sub-maximal estimation by ~ 1MET and ~ 2 METs, respectively (p < 0.001). The revised 2008 WFI sub-maximal treadmill estimation was found to accurately estimate peak VO 2 when compared to directly measured peak VO 2 . Conclusion: Accurate assessment of cardiopulmonary capacity is critical in determining appropriate duty assignments, and identification of potential cardiovascular problems, for firefighters. Estimation of cardiopulmonary fitness improves using the revised 2008 WFI sub-maximal equation. Background Every 23 seconds a fire in the United Sta tes requires the services of a career or volunteer fire department [1]. Sudden cardiac death is the most common cause of on- duty death among firefighters and occurs at higher rates than those found in similar occupations, such as police and emergency medical services [2]. A joint task force of the International Association of Firefighters (IAFF) and International Association of Fire Chiefs developed the Fire Service Joint Labor Manage- ment Wellness-Fitness Initiative (WFI) in 1997. Revi- sions in the 1999 and 2008 WFI recognize the firefighter as the “most important asset” inthefireser- vice, and its intent is to improve firefighter function, on- duty effectiveness, and overall quality of life, while redu- cing morbidity and mortality related to fire fighting [3]. A major component of the WFI is assessment of fire- fighters’ cardiopulmonary capacity, with a stepmill test, sub-maximal, or a maximal exercise treadmill test. The WFI mandates that firefighters have a maximal exercise test at age 40 and every other year thereafter. The maxi- mal exercise test is intended to measure peak VO 2 (measured as ml/kg -1 ·min -1 ), which is an objective, clini- cal measure that defines the limits of cardiopulmonary function. Peak VO 2 reflects an individual’sabilityto increase their heart rate and stroke volume, and redirect oxygenated blood to muscles for work on demand. Exer- cising at level s beyond which the cardiopulmonary sys- tem can adequately supply oxygen (commonly termed the anaerobic or ventilatory threshold, or VT) involves progressively greater degrees of oxygen-independent muscle metabolism, which is dramatically less efficient than aerobic metabolism, and can compromise cardio- vascular function [4]. Quantifying the energy demands of firefighting during fire suppression is difficult due to the inherent dangers of fire suppression tasks. Most efforts to define the arduous physical work demand requirements during firefighting have been focused on establishing the level of metabolic equivalents (METs) (1 MET ≈ 3.5 ml of O 2 /kg/min) using simulated tasks. A MET is a multiple of the resting metabolic rate and is commonly estimated using standardized equations [4]. 10 METs is roughly equivalent to jogging a 10-minute mile; 14 METs is * Correspondence: mochadana@aol.com 1 Department of Community Health Systems, School of Nursing, University of California, 2 Koret Way, San Francisco, California 94143, USA Full list of author information is available at the end of the article Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 © 2011 Drew-Nord et al; licensee BioMed Central Ltd. This is an Ope n Access article distributed under the terms of the Creative Commons Attribution License (http://creativeco mmons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original wor k is prope rly cited. similar to many extended competitive ac tivities such as running or rowing competitively, or bicycle racing at a high level [5]. The estimated METs proposed for fire- fighting range from 9.6 [6] to 14 [7] (a peak VO 2 range of 33.6 ml/kg -1 min -1 ·to 49 ml/kg -1 ·min -1 ). Recent analy- sis of physical aptitude tests among firefighter recruits demonstrated that male recruits’ average VO 2 require- ment was 38.5 ml/kg -1 ·min -1 (11 METs) to complete a timed simulated firefighting assessment course [8]. Mea- surement of functional capacity in 23 firefighters sug- gested that a mean of 41.54 ml/kg -1 ·min -1 (11.9 METs) is required to complete standard fire suppression tasks while wearing personal protective equipment [9]. Firefighting work demands can be extreme and accu- rate assessment of cardiopulmonary status, as well as detection and treatment of any underlying cardiovascu- lar disease, is critical to insure firefighter fitness for duty and prevent on-duty cardiac events or death. The 1999 WFI sub-maximal exercise test was found to overesti- mate true peak VO 2 in individual firefighters [10]. Con- cern about overestimation led to a revised equation for estimating peak VO 2 from sub-maximal exercise tread- mill tests in the 2008 WFI. Materials and methods Given that previous sub-maximal exercise test results in the WFI were shown to overestimate peak VO 2 ,andthat the WFI maximal exercise treadmill protocol has not been validated for accurac y in the literature, this study was undertaken to assess the validity of both the maximal and revised sub-maximal exercise treadmill peak VO 2 estimates in firefighters. Specifically, the present study tested the following comparisons: (a) estimated maximal heart rate (220 - age) to actual measured maximal heart rate; (b) WFI maximal exercise estimated peak VO 2 to directly measured peak VO 2 ;c)averagedpre-revision sub-maximal estimated peak VO 2 to revised sub-maximal estimated peak VO 2 ; and (d) directly measured peak VO 2 to revised WFI sub-maximal estimated peak VO 2 . Study Setting and Participants The study setting was a medium-sized suburban fire department in the eastern region of the San Francisco Bay Area in northern California. This department serves approximately 163,000 citizens and covers 46 square miles. All firefighters (N =105)assignedtosuppression duties were recruited, including firefighters, firefighter/ paramedics, firefighter/engineers, firefighter/captains and battalion chiefs. There were no women suppression fire- fighters in the department studied. This is consistent with national career firefighter statistics as women only represent approximately 4.5% of the fire service [11]. All testing took place during a five-week period between December 2008 and January 2009. Inclusion criteria for participation required that each participant had successfully completed a WFI examina- tion within the previous nine months and achieved a minimum of 10 METs (peak VO 2 of 35 ml/kg/min), on either a sub-maximal (using the pre-2008 equation), or maximal exercise treadmill test. Exclusion criteria included injury, illness, or scheduling conflicts that pre- cluded testing during the study period. The final study pop ulation consi sted of 83 male career firefighter s from all suppression ranks in this department. The study was conducted with approval of the Univer- sity of California San Francisco Committee on Human Research. Signed informed consents were obtained and all testing was conducted during on-duty hours with the approval of the department and union local. Testing occurred at an occupational health clinic where previous WFI examinations for this fire depart- ment had been conducted. A physician board certified in internal medicine and occupational medicine, and a nurse practitioner experienced in exercise testing, per- formed all treadmills and direct VO 2 measurements. Participants arrived on the day of scheduled testing with their assigned duty crew, with gym clothes and runn ing shoes appropriate for completing a maximal exercise test. Measurements Data collection consisted of medical record abstraction for demographics, cardiovascular risk factors and exer- cise test information. Demographic characteristics included age, rank, and years of fire service. Definitions of cardiovascular risk factors were obtained from the American Heart Association, Adult Treatment Panel III (ATP III), The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7), and the Cen- ters for Disease Control and Prevention [12-15]. All serum samples were analyzed at the same hospital-based certified laboratory (Centers for Medicare and Medicaid Services Clinical Laboratory Improvements Amend- ments (CLIA)). Cardiovascular risk factors of the partici- pants are summarized in Table 1. Maximal Heart Rates Maximal estimated heart rates were calculated as 220- age. Directly measured maximal heart rates were deter- minedfromtheelectrocardiogramatthepointofvoli- tional fatigue as determined by the firefighter and corroborated by the direct VO 2 assessment indicating that they had crossed the VT. Maximal Exercise Treadmill with Direct Peak VO 2 Assessment All 83 participants completed a maximal exercise test using the 2008 WFI Protocol with concurrent direct peak VO 2 measurements. Maximal exercise treadmill Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 Page 2 of 6 tests were considered complete when the firefighter indicated volitional fatigue (n = 83, see above), or if ter- minated by the testing physician due to concerns about cardiopulmonary distress (n = 0). The WFI protocol is a modified ramp protocol comprised of a 3-minute warm- up period at 3 mph - 0% grade, followed by fifteen 1- minute stages. Stage 1 begins at 4.5 mph and 0% grade, with the treadmill incline increasing 2% and speed increasing by 0.5 mph alternately in stages 2 through 15. The WFI maximal exercise treadmill estimates peak VO 2 based on the American College of Sports Medicine metabolic equation for running [16]. Peak VO 2 was obtained using the Cardio Coach CO 2 ™ VO 2 Fitness Assessment System, Model 9001- RMR (Korr Medical Technologies, Salt Lake City, Utah). The Cardio Coach CO 2 ™ is an economical, portable metabolic testing device that is feasible for use in a clinic and has been previously validated for measurement of peak VO 2 levels [17,18]. The Cardio Coach CO 2 TM is a dual gas analyzer (O 2 and CO 2 )that automatically calibrates to standar d temperature and pressure, dry at the beginning o f each testing cycl e. The Cardio Coach CO 2 ™ measures heart rate using the Polar T-31 heart monitor (Polar, I nc., Lake Suc- cess, NY). Heart rate and VO 2 (ml/kg -1 ·min -1 ), VCO 2 (ml/kg -1 ·min -1 ), VE/VO 2, VE/VCO 2 ,VEinL/min, FeO 2 %, Fe CO 2 %, and respiratory exchange ratio are graphically reported every 15 seconds. The Cardio Coach CO 2 ™ uses the ventilatory equivalents method (Ve/VO 2 ) to detect VT (Korr Medical Technologies, 2009). Revised Sub-maximal Exercise Treadmill Assessments In the latter part of 2008, the WFI introduced a revised equation for estimating peak VO 2 :peakVO 2 = 56.981 + (1.242 × TT) - (0.8 05 × BMI), where TT is the test time required to achieve target heart rate, and BMI is Body Mass Index. The 2008 WFI calculates target sub-maxi- mal heart rate (208 - (0.7 × age) × 0.85, whereas pre- vious sub-maximal heart rates were based on (220-age) × 0.85 [3,19]. Of the 83 firefighters who volunteered for the maxi- mal exercise treadmill tests and directly measured peak VO 2 , 63 subsequently completely their annually sched- uled WFI examination, which included a sub-maximal exercise treadmill test, within the subsequent four to eight weeks. These subsequent WFI sub-maximal exer- cise treadmill tests, using the revised equation, took place under identical conditions as the study WFI maxi- mal exercise treadmill tests but without the direct VO 2 measurement. The sub-maximal test uses the WFI treadmill protocol (see above) but terminates 15 seconds after the firefighter reaches their target heart rate. Pre-revision Sub-maximal Exercise Treadmill Assessments Prior to the 2008 WFI revision there was no published equation for the estimation of peak VO 2 from the sub- maximal exercise treadmill. The estimated peak VO 2 was determined by duration of the test and stage achieved [19]. Between one and seven historical sub- maximal test results were available for each of the 63 participants, and were averaged to create comparative historical variables. Procedure Participant’s height, weight and resting blood pressure was measured. A resting electrocardiogram (ECG) was completed, using the Welch-Allyn Schiller AT-10 6- Channel electrocardiograph/treadmill (San Diego, Cali- fornia). Upon completion of the resting ECG the Mason- Likar lead configuration was modifi ed to accommodat e the exercise treadmi ll [4]. The participant was then fitted with the appropriate 2-way non-rebreathable mask (Hans-Rudolph, Inc., Shawnee, Kansas). The mask com- pletely covered the nose and mouth of the participant and was checked for air leaks to eliminate extraneous room air from affecting the interpretation of peak VO 2 . A standing electrocardiogram was obtained and the treadmill was initiated. At test termination the firefigh ter recovered in the supine position. Available data from the maximal exercise treadmills is detailed in Table 2. Statistical Analyses Prior to all analysis all data were examined using stem and leaf plots and found to have normal distribution. Table 1 Participant Cardiovascular Risk Factor Profile - Maximal Exercise Treadmill-Peak VO 2 Assessment (n = 83) Risk Factor Mean, SD Body Mass Index (kg/m 2 ) 28.2 (± 3.9) Systolic BP 117 (± 10) Diastolic BP 69 (± 7) Total Cholesterol* (mg/dL) 197 (± 38) HDL** (mg/dL) 47 (± 11) LDL** (mg/dL) 126 (± 36) Cholesterol/HDL Ratio 4.35 (± 1.17) Triglycerides (mg/dL) 118 (± 70) *-fasting **- HDL - high density lipoprotein; LDL - low density lipoprotein Table 2 Maximal Exercise Treadmill Data (n = 83) Minimum Maximum Mean, SD Resting Systolic 102 164 122 (±10) Resting Diastolic 60 100 73 (±8) Resting Heart Rate 42 91 63 (±10) Maximal Heart Rate 130 194 174 (±10) Peak VO 2 Actual 26.3 69.5 43.6 (±9.1) RER* - Peak Exercise 0.90 1.28 1.09 (± .07) * - Respiratory Exchange Ratio Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 Page 3 of 6 Dependent t-tests were conducted on all 83 participants to test for differences between: 1) Estimated maximal heart rate (220 - age) and directly measured maximal heart rate. 2) WFI maximal exercise treadmill estimated peak VO 2 and directly measured peak VO 2 . Additional dependent t-tests were conducted on the results of the 63 participants who subsequently per- formed a revised WFI sub-maximal exercise treadmill test for differences between: 1) Averaged pre-revision WFI sub-maximal exercise treadmill estimated peak VO 2 mean (converted to METs) to revised WFI sub-maximal exercise tread- mill estimated peak VO 2 (converted to METs). 2) Directly measured peak VO 2 (converted to METs) to revised WFI sub-maximal exercise treadmill esti- mated peak VO 2 (converted to METs). All dependent t-tests were two tailed, with a =0.05 used for statistical significance. Statistical analyses were performed using SPSS Version 15.0 (SPSS, Inc., Chicago, Illinois). Results There were 105 active suppression male career firefigh- ters eligible for participation in the study. Of those, five were new hires who had not completed a WFI examina- tion. Six firefighters chose not to participate; of the 94 choosing to participate 11 could not be scheduled for maximal exercise tests due to injury, illness or schedul- ing conflicts resulting in an n =83forthisstudy.The participants’ ages ranged from 26 to 57 years with a mean of 41.1; 94% of the participants were Caucasian, and 6% were Hispanic or African-American. The years of firefighting ranged from 2 to 34 with a mean of 15.6. Maximal Estimates and Measurements The traditional maximal heart rate estimation (220 - age) was significantly higher than measured maximal heart rate (178.6 vs. 173.6 with a mean difference of 4.96 beats/min, p < 0.001, 95% CI: 3.03, 6.90). Estimated peak VO 2 was significantly higher than directly mea- sured peak VO 2 (47.7 vs. 43.6, with a mean difference of 4.06 ml/kg/min, (1.16 METs) p < 0.001, 95% CI: 2.88, 5.23). Sub-maximal Estimates and Measurements Within four to eight weeks of the maximal exercise treadmill tests 63 participants completed a sub-maximal exercise treadmill test (using the revised 2008 WFI equatio n). Their average age was 40.19 years (± 6.9) and average years of firefighting was 14.4 (± 6.8). All firefigh- ter suppression ranks were represented in this sub- group. The subsequent examination allowed for compar- ison of the revised sub-maximal exercise treadmill peak VO 2 estimate to an averaged pre-revision (comparative historical variable) sub-maximal exercise treadmill peak VO 2 estimate and the recently obtained directly mea- sured peak VO 2 . For simplicity in reporting sub-maxi- mal results all peak VO 2 results were convert ed to METs (peak VO 2 /3.5). A statistically significant difference was found between pre-revision sub maximal exerci se treadmill peak METs mean estimates and revised sub-maximal peak METs estimates (14.81 vs. 12.58, with a mean difference of 2.23 METs, p < 0.001, 95% CI: 1.86, 2.59) These findings support previous research determining that WFI sub- maximal peak METs estimates prior to the 2008 revi- sion were overestimated [10]. Revised sub-maximal treadmill METs estimates did not differ from directly measured maximal exercise treadmill METs, indicating that the revised 2008 estimating equation is a reasonable estimate of METs (12.64 vs. 12.58 with a mean differ- ence of .07 METs, p ≤ .76, 95% CI: 39, .54) This repre- sents additional validation of the accuracy of the new estimating equation [3]. All maximal and sub-maximal comparisons are summarized in Table 3. Discussion Fire departments often struggle to determine fitness for duty for their members who return from an injury or ill- ness, prepare to embark on wildland strike teams, heavy rescue missions, or for daily work assignments. There are ongoing efforts to define minimally acceptable and safe fitness levels; levels that should be informed by the energy requirements needed during a firefighter’stour of duty. Maximum directly measured METs for the fire- figh ters in this study ranged from 7.5 to 19.9, indicating that some participants might have a difficult time meet- ing the demands of the job while others appear ade- quately fit. Four different methods of cardiopulmonary assessment are compared here: direct measurement of peak VO 2 , estimated peak VO 2 derived from a maximal exercise treadmill equation, historical average of pre- revision estimated peak VO 2 sub-maximal exercise treadmills, and estimated peak VO 2 derived from the rev ised (2008) sub-maximal exercise treadmill equation. Directly measured peak VO 2 is the most objective and considered the “gold standard” of the four methods [4]. The difference observed in maximum heart rate between directly me asured maximum heart rate (while wearing a non-rebreathable mask), and a 220-age esti- mated maximum heart rate (part of the maximal exer- cise treadmill estimation equation) provides some explanation for the over-estimation. Estimated maximal Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 Page 4 of 6 heart rates were about 5 beats per minute higher than those measured during peak exercise. H eart rates are a method used on the fire ground to evaluate a firefigh- ters’ capability to re-enter the fire scene. Using target heart rates that exceed true maximums, or percentages of estimated maximum heart rates that are inaccurate, could result in dangerous duty assignments. Assessment of direct peak VO 2 and maximal exercise treadmill results indicate that the equation utilized by the WFI maximal treadmill over-estimates peak VO 2 by an average of 4.06 ml/kg -1 ·min -1 , or approximately 1 MET. If a firefighter’ s fitness level is less than optimal, or if they have underlying cardiovascular disease, this overestimation could lead to on-duty clearances that could prove compromising. Revised sub-maximal ex ercise treadmill peak VO2 estimates were compared to averaged pre-revision his- torical sub-maximal exercise peak VO 2 estimates. The average overestimation of the historical mean was approximately 2 METs. This finding supports the Mier andGibsonreport(2004)thatthepre-revisionWFI sub-maximal treadmill equation overestimated peak VO 2 , and that those equation results should be used with caution for duty assignment decisions. The comparison of directly measured peak VO 2 to the revised sub-maximal exercise treadmill peak VO 2 esti- mates (n = 63) found that there were no differences between the two assessment methods. When comparing revised WFI sub-maximal exercise treadmill peak VO 2 estimates to previous years of testing, or to reports in the literature, careful consideration must be given to which estimation method was used. The same task, measured with different estimating equations, can result in different results as demonstrated herein. Limitations and Strengths The limitations of our study include the self-selection bias of the participants, the limited gender and ethnic demographics of the group (all male, predominantly Cau- casian), and the range in number of historical sub- maximal exercise treadmill VO 2 estimates, resulting in a less than ideal comparison g roup. While testing was completed within a four month period, it included the winter holiday season which may have had a seasonal influence on fitness behavior (resulting in an increase or decrease in exercise intensity). The composition of the sample is reflective of the department in terms of gender and ethnicity. There is an average four to eight week gap between the direct measure peak VO 2 and the sub-maxi- mal exercise treadmill peak VO 2 assessment without any documentation of fitness behaviors. Ho wever, any fitness improvement on the part of firefighters in the interim would have directed the results towards the null. The strengths of our study include the number of parti- cipants, their range in age, rank, firefighting experience, and their experience with the WFI protocol. The avail- ability of seven years historical data can be viewed as a strength. Use of the mask to measure peak VO 2 was familiar to the participants as they routinely work with self-contained breathing apparatus. The ability to per- form all testing components w hile on duty encourage d participation. There were no incentives of fered for parti- cipation. All testing was completed in the same facility using the same equipment and personnel, thus increasing consistency of testing and inter-rater reliability. Clinical Implications Firefighters who have been tested using earlier estimation equations may requ ire careful explanation as to a notice- able drop in test results when using the revised 2008 WFI equation. Participants are likely to be disappointed to see a reduction in their “fitness level” when they have not chan- ged their patterns, nor workout habits, between testing cycles. Again, if a fire fighter falls into the lower fitness categories, or has underlying cardiovascular disease, inac- curate estimates could contribute to cardiac compromise. Conclusions In order to protect firefighters from potentially life- threatening cardiac situations it is imperative that Table 3 Comparisons: Heart Rate, Peak VO 2 , Estimated METs n Mean SD SEM 95% CI Lower 95% CI Upper t d Sig(2-tailed) Estimated Max. HR: Actual Max. 83 4.96 8.87 .97 3.03 6.9 5.09 82 .00 HR Estimated peak VO 2 : Direct measure peak VO 2 83 4.06 5.39 .59 2.88 5.23 6.85 82 .00 Pre-revision METs Est.: Revised METs estimate 63 2.23 1.46 .18 1.86 2.59 12.14 62 .00 Direct METs: Revised Sub-maximal METs estimate 63 .07 1.85 .23 39 .54 .31 62 .76 Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 Page 5 of 6 exercise testing r esults are accurate, whether the test is being used for duty assignment or part of a comprehen- sive risk assessment. The results from the revised sub- maximal exercise treadmill estimation equation appear to accurately reflect directly measured peak VO 2 results. WFI maximal treadmill peak VO 2 estimates should be interpreted with caution, especially as they appear to over-estimateMETsbyanaverageof1.Giventhe potential for over-estimationoffitness,providerswho make fitness-for-duty assessments should consider the energy requirements of the job, any underlying cardio- vascular risk factors, and the method of testing used when recommending return to, or continuation of, duties. These findings support the continuation and further expansion of reliable exercise testing of firefigh- ters, within the context of a cardiovascular disease pre- vention program such as the WFI. Performing measured peak VO 2 and maximal exercise treadmill tests can be challenging for fire departments to accomplish due to limited resources. The 2008 WFI sub-maximal exercise t readmill test can be safely admi- nistered outside of a medical setting using tools that are often available within the fire department (treadmill, stopwatch, and Polar heart monitor). Disadvantages of the sub-maximal treadmill test are the limited means for assessing underlying cardiovascular conditions, and the inability to determine maximal cardiovascular perfor- mance directly. However, the revised 2008 sub-maximal treadmill peak VO 2 estimation equation is a valid tool to assess interim progress in cardiovascular training programs. Acknowledgements The corresponding author would like to thank the Livermore-Pleasanton Fire Department administration, suppression, and support staff for their trust, enthusiasm, and participation in this project; the National Institute for Occupational Safety and Health (Grant #T42 OH 008429) for its traineeship support; and the UCSF School of Nursing Century Club for its financial support. Author details 1 Department of Community Health Systems, School of Nursing, University of California, 2 Koret Way, San Francisco, California 94143, USA. 2 School of Medicine, Stanford University, Palo Alto VA Health Care System, 3801 Miranda Avenue, Palo Alto, California 94304-1290, USA. 3 Premier COMP Medical Group, Inc. 5635 W. Las Positas Blvd., Suite 401, Pleasanton, CA 94588, USA. 4 Palo Alto VA Health Care System, 3801Miranda Avenue, Palo Alto, California 94304-1290, USA. 5 Department of Physiological Nursing, School of Nursing, University of California, 2 Koret Way, San Francisco, California 94143, USA. Authors’ contributions All of the authors contributed substantially to the conception, design, data acquisition and analysis, manuscript drafts and revisions of this study. Each has given final approval for publication. Competing interests Dr. Drew-Nord and Dr. Nord own the occupational medicine practice where this research was conducted and contract with various fire agencies to provide WFI services. This relationship was determined to represent no conflict of interest by the Institutional Review Board of the University of California, San Francisco. The remaining authors declare that they have no competing interests. Received: 6 October 2010 Accepted: 25 September 2011 Published: 25 September 2011 References 1. Firefighter Statistics. [http://www.usfa.dhs.gov/statistics/estimates/nfpa/ index.shtm], retreived August 3, 2011. 2. United States Fire Administration: Firefighter Fatality Retrospective Study, April 2002/FA-220.Edited by: Corporation T: Firefighter Fatality Retrospective Study 2006. 3. Fire Service Joint Labor Management Wellness-Fitness Initiative. [http:// www.iaff.org/HS/Well/wellness.html]. 4. Froelicher VF, Myers J: Exercise and the heart. Philadelphia: Saunders Elsevier;, 5 2006. 5. Fletcher GF, Froelicher VF, Hartley LH, Haskell WL, Pollock ML: Exercise standards. A statement for health professionals from the American Heart Association. Circulation 1990, 82:2286-2322. 6. Sothmann MS, Saupe K, Jasenof D, Blaney J: Heart rate response of firefighters to actual emergencies. Implications for cardiorespiratory fitness. J Occup Med 1992, 34(8):797-800. 7. Malley KS, Goldstein AM, Aldrich TK, Kelly KJ, Weiden M, Coplan N, Karwa ML, Prezant DJ: Effects of fire fighting uniform (modern, modified modern, and traditional) design changes on exercise duration in New York City Firefighters. J Occup Environ Med 1999, 41(12):1104-1115. 8. Williams-Bell FM, Villar R, Sharratt M, Hughson RL: Physiological demands of the firefighter candidate physical ability test. Medicine and Science in Sports and Exercise 2009, 41:653-662. 9. Adams J, Roberts J, Simms K, Cheng D, Hartman J, Bartlett C: Measurement of functional capacity requirements to aid in the development of an occupation-specific rehabilitation training program to help firefighters with cardiac disease safely return to work. American Journal of Cardiology 2009, 103:762-765. 10. Mier CM, Gibson AL: Evaluation of a treadmill test for predicting the aerobic capacity of firefighters. Occup Med (Lond) 2004, 54(6):373-378. 11. Women in the fire service. [http://www.nfpa.org/itemDetail.asp? categoryID=955&itemID=23601&URL=Research/Fire%20statistics/The%20U.S. %20fire%20service&cookie%5Ftest=1], retrieved August 3, 2011. 12. Men and cardiovascular disease risk factors. [http://www.heart.org/ HEARTORG/Conditions/HeartAttack/UnderstandYourRiskofHeartAttack/ Understand-Your-Risk-of-Heart-Attack_UCM_002040_Article.jsp], retrieved August 3, 2011. 13. Healthy weight - it’s not a diet, it’s a lifestyle!. [http://www.cdc.gov/ healthyweight/assessing/bmi/adult_bmi/index.html#Interpreted]. 14. Third report of the expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (ATP III). [http://hp2010.nhlbihin.net/ atpiii/calculator.asp?usertype=prof]. 15. National Institute of Health National Heart Lung and Blood Institute: JNC7 Guidelines. 2006. 16. American College of Sports Medicine: Guidelines for exercise testing and prescription. Baltimore: Lippincott, Williams & Wilkins;, 6 2000. 17. Jensky NE, Vallejo AF, Ong MD, Schroeder ET: Validation of the Cardio Coach for sub-maximal and maximal metabolic exercise testing. Medicine and Science in Sports and Exercise 2005, 37(5):S231. 18. Dieli-Conwright CM, Jensky NE, Battaglia GM, McCauley SA, Schroeder ET: Validation of the CardioCoach CO2 for submaximal and maximal metabolic exercise testing. The Journal of Strength and Conditioning Research 2009, 23:1316-1320. 19. International Association of Fire Fighters: The Fire Service Joint Labor Management Wellness-Fitness Initiative. Washington, D.C.: International Association of Fire Fighters;, 2 1999. doi:10.1186/1745-6673-6-25 Cite this article as: Drew-Nord et al.: Accuracy of peak VO2 assessments in career firefighters. Journal of Occupational Medicine and Toxicology 2011 6:25. Drew-Nord et al. Journal of Occupational Medicine and Toxicology 2011, 6:25 http://www.occup-med.com/content/6/1/25 Page 6 of 6 . There were no incentives of fered for parti- cipation. All testing was completed in the same facility using the same equipment and personnel, thus increasing consistency of testing and inter-rater. determined to represent no conflict of interest by the Institutional Review Board of the University of California, San Francisco. The remaining authors declare that they have no competing interests. Received:. Initiative. Washington, D.C.: International Association of Fire Fighters;, 2 1999. doi:10.1186/1745-6673-6-25 Cite this article as: Drew-Nord et al.: Accuracy of peak VO2 assessments in career firefighters.