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  • Cover Page

  • Table of Contents

  • Biomass Utilization, Limits of

    • Biomass Utilization, Limits of

      • Glossary

      • Biomass Resources

        • World Biomass

        • United States Biomass

        • United States Agricultural and Forest Products and Biofuels

      • Conversion of Biomass Resources

        • Direct Heating

        • Health Effects

        • Ethanol Production

      • Biogas

        • Biogas for Smallholders

        • Gasification

        • Pyrolysis

        • Vegetable Oil

        • Electricity

      • Biomass and the Environment

        • Soil Erosion

        • Forest Land Erosion

        • Nutrient Losses and Water Pollution

        • Water Use

        • Air Pollution

      • Social and Economic Impacts

      • Conclusion

      • Acknowledgment

      • See also the Following Articles

      • References

  • Biomass, Bioengineering of

    • Biomass, Bioengineering of

      • Glossary

      • Background

      • Characteristics of Biomass

        • Production of Biomass

          • Natural Inputs to Biomass Production

          • Potential and Actual Yields of Biomass

          • Comparison of Biomass and Petroleum

          • Cost of Biomass versus Fossil Feedstocks

        • Major Types of Biomass: Their Production and Composition

          • Sugar Crops

          • Starch Crops

          • Plant Oil and Protein Crops

          • Tree and Fiber Crops

          • Forage and Grass Crops

        • Biotechnology and Biomass Production

          • Modify Biomass Composition for Easier Processing

          • Enhance Biomass Yields and Reduce Inputs

          • New Products

      • Uses of Biomass

        • Current Uses

          • Food/Feed Consumption and World Protein/Calorie Demand

          • Animal Feeds

          • Existing Fuels/Chemicals/Materials Uses of Biomass

        • New and Developing Uses of Biomass

          • New Chemicals and Materials Uses

          • New Liquid Fuels from Biomass

          • Land Requirements for Fuel Production

          • Cost of Liquid Fuel Production from Biomass

      • Bioprocessing of Biomass

        • Historical Lessons from the Chemical and Petroleum Processing Industries

          • Importance of Raw Material and Processing Costs for Commodities

          • Need for Complete Raw Material Utilization

          • Incremental Process Improvement

          • Innovation and Risk

        • Current Status of Biomass Processing

        • Priorities for Developing Lignocellulose Biorefineries

          • Enhancing Yield and Feedstock Modification

          • New Technologies Needed for Low Cost Lignocellulose Conversion

          • Generic Biomass Processing Technologies

      • Potential and Limitations of Biomass and Biobased Industrial Products

        • Potential Benefits

        • Potential Limitations of Biomass and Biobased Industrial Products

        • Achieving the Benefits of Biobased Products

      • See also the Following Articles

      • References

  • Biomaterials, Synthetic Synthesis, Fabrication, and Applications

    • Biomaterials, Synthetic Synthesis, Fabrication, and Applications

      • Glossary

      • Introduction to Medical Biomaterials

      • Aspects of the Structural Chemistry of Natural Materials Used in the Human Body

        • Natural Polymers

        • Natural Pliant Composites

        • Natural Mineralized Tissues, Bone, Cartilage, and Enamel

      • General Repair Mechanisms and Biocompatibility

      • Materials of Construction

        • Synthetic Polymers

          • Synthesis

          • Polymer Modification

          • Biodegradable Polymers

        • Polymers from Natural Sources

        • Metals

        • Ceramics

          • Conventional Ceramics

          • Bioactive Ceramics

          • Toward Resorbable Implants

        • Composites

          • Composites Based on HAP

          • Bone Graft Materials

      • The Way Forward, Tissue Engineering

        • Prevention of Unwanted Tissue Interactions

        • Directing Tissue Formation

        • Large-Scale Culture of Therapeutic Cells

        • Future Directions

      • See also the Following Articles

      • References

  • Biomineralization and Biomimetic Materials

    • Biomineralization and Biomimetic Materials

      • Glossary

      • Structural Biological Materials

      • Structural Proteins

      • Structural Polysaccharides

      • Mineralized Tissues

        • Silica

        • Carbonate

        • Hydroxyapatite

      • Biological and Synthetic Processing

      • The Process of Biomineralization

      • Biomimetic Materials

        • Polymers

        • Surfactants and Self-Assembly

        • Inorganic Particle Formation

        • Tough-Layered Structures

        • Biomimetic Processing Methods

        • Cell Adhesion and Tissue Engineering

      • Applications of Biomimetic Materials

      • See also the Following Articles

      • References

  • Bioreactors

    • Bioreactors

      • Glossary

      • Introduction

      • Bioreactor Systems

        • Submerged Culture

          • Mechanically Stirred Tank Bioreactors

          • Bubble Columns

          • Airlift Bioreactors

          • Fluidized Beds

          • Packed Bed Bioreactors

          • Photobioreactors

          • Other Bioreactor Configurations

        • Solid-State Culture

        • Bioreactors for Immobilized Enzymes and Cells

      • Considerations for Bioreactor Design

        • General Features

        • Mixing, Heat, and Mass Transfer

          • Mixing and Shear Effects

          • Oxygen Supply and Carbon Dioxide Removal

          • Heat Removal and Temperature Control

        • Monoseptic Operation, Cleaning, Sterilization

        • Operational Modes of Bioreactors

        • Medium Composition

        • Kinetics, Productivity, and Bioreactors

          • Cell Growth

          • Productivity

          • Enzyme Kinetics

      • Concluding Remarks

      • See also the Following Articles

      • References

  • Fiber-Optic Chemical Sensors

    • Fiber-Optic Chemical Sensors

      • Glossary

      • Introduction

      • Fundamental Principles of Fiber-Optic Chemical Sensors

        • Optical Fibers

          • Basic Characteristics

          • Optical Fiber Types

          • Optical Fiber Configurations

        • Fiber-Optic Chemical Sensor Design and Instrumentation

          • Light Sources

          • Optical Signal Detectors

        • Optical Phenomena Employed for Sensing in Fiber-Optic Chemical Sensors

          • Absorption

          • Fluorescence

          • Time-Resolved Fluorescence Spectroscopy

          • Fluorescence Energy Transfer

          • Raman Spectroscopy

          • Surface Plasmon Resonance (SPR)

          • Evanescent Wave Spectroscopy

      • Sensing Schemes for Fiber-Optic Chemical Sensors

        • Intrinsic Sensing Mechanism—Direct Spectroscopy

          • Liquid-Phase Sensing

          • Gas-Phase Sensing

        • Extrinsic Sensing Mechanism—Indicator Chemistry

          • Chemical Sensing Reagent—Optrodes

            • pH sensing

            • Gas and vapor sensing

            • Ion sensing

          • Immobilization Techniques

            • Adsorption/electrostatic immobilization

            • Entrapment immobilization

            • Covalent immobilization

          • Biological Sensing Materials (Fiber-Optic Based Biosensors)

            • Biocatalysts as the recognition element in fiberoptic biosensor

            • Bioaffinity as the recognition mechanism in fiber-optic biosensors

      • Applications of Fiber-Optic Chemical Sensors

        • Clinical Applications

          • Fiber-Optic Chemical Sensors for in Vivo Analysis

          • Clinical Fiber-Optic Chemical Sensors for in Situ Sample Analysis

        • Environmental Fiber-Optic Chemical Sensors

        • Industrial and Bioprocess Control Applications

      • Recent Developments

        • Multianalyte Sensing

        • Distributed Chemical Sensing

        • Imaging and Chemical Sensing

      • Conclusions

      • See also the Following Articles

      • References

  • Hybridomas, Genetic Engineering of

    • Hybridomas, Genetic Engineering of

      • Glossary

      • Introduction: the Nature of Antibodies

      • The Molecular Structure of Antibodies

      • Glycosylation of Antibodies

      • Production of Monoclonal Antibodies

      • Immunization in Vivo

      • Immunization in Vitro

      • The Development of Cell Hybridization

      • Methods of Cell Fusion

      • Cell Fusion to Immortalize Lymphocytes

      • Selectable Gene Markers for Cell Selection

      • Clonal Selection of Mab-Secreting Hybridomas

      • Assay of Monoclonal Antibodies

        • Enzyme-Linked Immunosorbent Assay (ELISA)

        • Radioimmunoassay (RIA)

        • Affinity Binding

      • Human Monoclonal Antibodies

        • The Source of Antibody-Secreting Lymphocytes

        • Immortalization and Chromosome Instability

        • Antibody Secretion of Human Parental Fusion Partners

      • Recombinant Antibodies

      • Recombinant Antibody Fragments

      • Therapeutic Antibodies

      • Antibodies from Plants

      • Humanized Antibodies from Transgenic Mice

      • The Importance of Glycosylation to Therapeutic Antibodies

      • Large-Scale Production of Monoclonal Antibodies from Hybridomas

        • In Vivo (Ascites) Production of Monoclonal Antibodies (Mabs)

        • In Vitro Production

        • Stirred-Tank Bioreactor

        • The Airlift Fermenter

      • The Control of Culture Parameters

        • Agitation

        • Culture pH

        • Oxygen

      • Serum and Serum-Free Medium for Antibody Production from Hybridomas

        • Serum-Free Media

      • Conclusions

      • See also the Following Articles

      • References

  • Image-Guided Surgery

    • Image-Guided Surgery

      • Glossary

      • Image-Guidance Methods and Technologies

      • Intraoperative Imaging

      • Intraoperative Magnetic Resonance Imaging

      • Image-Guided Neurosurgery

      • Thermal Ablations

        • Interstitial Laser Therapy

        • Focused Ultrasound Surgery

      • Cryoablation

      • Conclusion

      • Acknowledgments

      • See also the Following Articles

      • References

  • Mammalian Cell Culture

    • Mammalian Cell Culture

      • Glossary

      • Introduction

      • The Cell

        • Cell Types

        • Cell Lines

        • Hybrid Cell Lines

          • Hybridomas

          • Heterokayons

        • Recombinant Cell Lines

          • Nonviral DNA Transfer Vehicles for Mammalian Cells

          • Transfer of Genes of Interest into Mammalian Cells

          • Amplification of Transferred DNA Through Methotrexate Selection

          • Transient DNA Transfer into Mammalian Cells for Rapid Protein Synthesis

      • The Culture System

        • Reactors for Anchorage-Dependent Cells

          • Basic Culture Units

          • Multisurface Plate Units

          • High-Volume Units

            • Glass bead culture:

            • Microcarrier culture:

        • Bioreactors for Suspension Cells

          • Laboratory Scale

          • Scale-Up

            • Air-lift fermenter:

            • Celligen fermenter:

          • Large-Scale Bioreactors

        • High-Cell-Density Bioreactors

          • Hollow-Fiber Bioreactors

          • Spin Filters

          • Microporous Microcarriers

      • The Culture Production Process

      • Cell Products

        • Viral Vaccines

        • Antibodies

        • Immunoregulators

        • Recombinant Products

        • Cell and Tissue Therapy

          • Cell Therapy

          • Gene Therapy

        • Other Products

      • Applications of Cell Culture

      • Conclusion

      • See also the Following Articles

      • References

  • Metabolic Engineering

    • Metabolic Engineering

      • Glossary

      • Background

      • Introduction

      • Molecular Biology Tools

      • Metabolic Network Analysis

      • Metabolic Control Analysis

      • Tools from Functional Genomics

      • Applications of Metabolic Engineering

        • Heterologous Protein Production

        • Extension of Substrate Range

        • Pathways Leading to New Products

        • Pathways for Degradation of Xenobiotics

        • Engineering of Cellular Physiology for Process Improvement

        • Elimination of By-Product Formation

        • Improvement of Yield or Productivity

      • Future Directions

      • Acknowledgment

      • See also the Following Articles

      • References

  • Microanalytical Assays

    • Microanalytical Assays

      • Glossary

      • Microfabrication

      • Biosensors

      • Biological Recognition Elements

      • Immobilization

      • Detector Elements

      • Optically Based Biosensors

      • Sensor Dynamics

      • Other Detectors

      • See also the Following Articles

      • References

  • Optical Fiber Techniques for Medical Applications

    • Optical Fiber Techniques for Medical Applications

      • Glossary

      • Introduction

      • Optical Fibers

        • Properties of Optical Fibers

          • Total lnternal Reflection

          • Optical Fibers

          • Transmission in Optical Fibers

        • Material and Methods of Fabrication of Optical Fibers

          • Optical Fibers Made of Silica Glass

          • Special Optical Fibers

      • Lasers for Fiberoptic Medical Systems

        • Medical Lasers

        • The Use of Various Lasers in Medicine

        • Lasers and Fibers

      • Fiberoptic Endoscopes

        • Light Guides for Illumination

          • Light Sources

          • Light Guides (Nonordered Bundles)

        • Ordered Bundles for Image Transmission

        • Fabrication of Fiberoptic Bundles

        • Fiberscopes and Endoscopes

        • Clinical Applications of Endoscopes

          • Standard Endoscopes

          • Thin and Ultrathin Endoscopes

      • Fiberoptic Medical Diagnostics

        • Diagnostic Systems

        • Direct Sensors

          • Physical Sensors

          • Chemical Sensors

        • Indirect Sensors

          • Physical Sensors

          • Chemical Sensors

      • Integrated Fiberoptic Systems

        • Power Fibers for Medical Systems

        • Laser Catheters

        • Laser Endoscopes

        • Robotic Systems

      • Laser–Fiberoptic Systems and their Clinical Applications

        • Gastroenterology

        • Urology

        • Gynecology

        • Fetal Diagnosis and Therapy

        • Cardiovascular and Heart Surgery

          • Laser Angioplasty Using Laser Catheters

          • Transmyocardial Revascularization

          • Closed Chest Endoscopic Surgery on a Beating Heart

        • Cancer Diagnoses and Photochemotherapy

      • Novel Fiberoptic Medical Systems

        • Time Resolved Phenomena

        • Optical Coherent Tomography

      • Outlook

      • See also the Following Articles

      • References

  • Pharmaceuticals, Controlled Release of

    • Pharmaceuticals, Controlled Release of

      • Glossary

      • Introduction/History

      • Methods of Achieving Controlled Release

        • Membrane Diffusion-Controlled Systems

        • Biodegradable Systems

        • Osmotic Systems

      • Important Controlled Release Products

        • Transdermal Systems

        • Nasal Spray/Inhalers

        • Targeted Drug Delivery

        • Implants

      • Future Directions

      • See also the following Articles

      • References

  • Pharmacokinetics

    • Pharmacokinetics

      • Glossary

      • Basic Pharmacokinetic Concepts

        • Half-Life

        • Volume of Distribution

        • Bioavailability

        • Mechanisms of Transport

      • Drug Absorption

        • Gastrointestinal Absorption

        • Transdermal, Subcutaneous, Intramuscular Routes of Absorption

        • Intraperitoneal Administration

        • Inhalation

        • Mathematical Approaches to the Description of Absorption and Bioavailability

      • Drug Distribution

        • Volume of Distribution

        • Binding

      • Drug Metabolism and Elimination

        • Renal Excretion

        • Hepatic Metabolism

        • Extrahepatic Metabolism

        • Biliary Excretion

      • Pharmacokinetic Variability

        • Pharmacokinetic Changes in the Elderly

        • Transplacental Transfer of Drugs

        • Renal Failure

        • Removal of Drugs by Dialysis

        • Patients with Liver Disease

        • Congestive Heart Failure Congestive Heart Failure Includes Cardiac

        • Patients with Burns

      • Quantitative Approaches to Pharmacokinetic Modeling

        • Compartmental Approaches

        • Physiologic Pharmacokinetic Models

        • Noncompartmental Model Approaches

      • See also the Following Articles

      • References

  • Separation and Purification of Biochemicals

    • Separation and Purification of Biochemicals

      • Glossary

      • Principles Of Chromatographic Separations

        • Basic Parameters

          • Parameters of the Chromatogram

          • Retention

          • Column Efficiency and Zone Width

          • Peak Asymmetry

          • Selectivity

          • Resolution

        • Separation by Stationary Phase Interaction

          • Ion Exchange Chromatography

          • Hydrophobic Interaction Chromatography

          • Reversed-Phase Chromatography

          • Hydroxyapatite Chromatography

        • Separation by Affinity (Biospecific Interactions)

          • Immobilized Metal Affinity Chromatography

          • Chiral Chromatography

        • Separation by Size

      • Process Design In Chromatography

        • The Different Modes of Chromatography

          • Gradient and Isocratic Elution Chromatography

          • Frontal Chromatography

          • Displacement Chromatography

        • Scale-Up Considerations

        • Processes for Preparative Chromatography

          • Expanded (Fluidized) Bed Chromatography

          • Radial Chromatography

          • Preparative-Continuous Annular Chromatography

          • Simulated Moving Bed

      • Stationary Phases For Biochromatography

        • Particle-Based Stationary Phases

          • Conventional Porous Particles

          • Particles with Reduced Mass Transfer Limitation

        • Continuous Stationary Phases

          • Membranes

          • Monoliths

      • See also the Following Articles

      • References

  • Tissue Engineering

    • Tissue Engineering

      • Glossary

      • A Brief History Of Tissue Engineering

      • Fundamentals Of Tissue Engineering

        • Biomaterial Design

          • Materials Used in Tissue Engineering

          • Optimization of Surface Chemistry

          • Fabrication of Porous Matrices

        • Cell Engineering

          • Growth Factors, Hormones, and Signal Transduction

          • Genetic Engineering

          • Metabolic Engineering

          • Effects of Mechanical Forces on Cells and Tissues

        • Transport Phenomena in Tissue Engineering

          • Cell Migration

          • Metabolite Transport

          • Bioreactor Technologies

            • Microcarrier-based systems.

            • Hollow-fiber systems.

            • Rotating vessel wall bioreactor.

        • Morphogenesis of Engineered Tissues

        • Summary

      • Applications Of Tissue Engineering

        • Connective Tissues

          • In Vitro Construction of Connective Tissues

          • In Vivo Regeneration Using Guidance Templates

          • Epithelial and Connective Tissue Composites

        • Epithelia and Endothelia

          • Secretory and Transport Functions of Epithelial and Endothelial Cells

          • Tissue Constructs Using Epithelial Cells

          • Epithelial and Connective Tissue Composites

        • Endocrine Tissues

      • Future Prospects For Tissue Engineering

      • See also the Following Articles

      • References

  • Toxicology in Forensic Science

    • Toxicology in Forensic Science

      • Glossary

      • Applications of Forensic Toxicology

      • Specimens

      • Chain of Custody

      • What Chemicals should be Targeted?

      • Techniques Used

      • Initial Tests and Confirmation

      • Quality Assurance and Validation

      • Reports

      • Interpretation of Toxicological Results

      • Artefacts in Analysis

        • Stability of Drugs

        • Bioconversion

        • Redistribution

      • Court Testimony and Expertise

      • See also the Following Articles

      • References

Nội dung

[...]... t) of topsoil This soil formation rate is the equivalent of about 1 t/ha/yr Forest soil re-formation is slower than in agriculture and is estimated to take more than 1000 years to produce 2.5 cm of soil The adverse effect of soil erosion is the gradual loss of productivity and eventually the abandonment of the land for crop production P1: FJU Revised Pages Encyclopedia of Physical Science and Technology. .. annual production of biomass FIGURE 3 World food and forage production (millions of tons) P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33 148 for these many food and feed uses, as well as available crop and forestry residues C Biotechnology and Biomass Production 1 Modify Biomass Composition for Easier Processing Plant breeding and/ or molecular... Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33 153 Biomass, Bioengineering of toxicity, but by high oxygen demands if processed in conventional sewage treatment facilities Solid wastes from biomass processing could occupy large volumes of landfill space, and would tend also produce high oxygen demand liquid effluents from landfills The volume of landfill space... Encyclopedia of Physical Science and Technology EN002C-60 May 17, 2001 20:23 171 Biomass Utilization, Limits of as to how much biomass can be harvested as an energy source without further causing the extinction of more plants, animals, and microbes because of biomass resources on which biodiversity depends Agriculture and managed forests occupy approximately 70% of the total land area and use about 70% of the... greater than the human demand Obviously, much of the plant matter we grow is used to feed animals, not people directly However, if we so chose, we could easily feed the world’s population with an adequate, plant-based, diet using a fraction of the land now devoted to agriculture and animal husbandry (There P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33... these tree and fiber crops and their residues are essentially all P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33 147 Biomass, Bioengineering of lignocellulosic materials, i.e., they are composed mostly of sugar polymers and lignin 5 Forage and Grass Crops For purposes of this article, we will not distinguish between grasses and legumes, but will consider... will follow B Major Types of Biomass: Their Production and Composition 1 Sugar Crops The major sugar crops are sugar cane and sugar beets Worldwide, approximately 100 million tons per year of sugar (sucrose) are produced from sugar cane and sugar beets Most of these sugars are used ultimately in human P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33... oilseeds and sugar crops 2 Animal Feeds In 1998 the United States produced about 40 million tons of beef, pork, and poultry as well as billions of dozens of eggs and tens of millions of tons of milk To generate these products, livestock and poultry consumed well over 500 million tons of feed expressed on a feeding value equivalent to corn Over half of this total feed was from forages, about two thirds of. .. chief source of fuel and materials With the coming of the Industrial Revolution, a gradual switch from biomass as the major fuel source took place, first through a transition to coal and later to petroleum and natural gas The oil P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33 150 refining industry was developed over about the last 120 years and catalyzed... biomass P1: GNH 2nd Revised Pages Encyclopedia of Physical Science and Technology EN002G-61 May 19, 2001 19:33 151 Biomass, Bioengineering of 2 New Liquid Fuels from Biomass Total consumption of gasoline and diesel fuel in the United States is about 150 billion gallons per year Assuming an average density of these liquid fuels of six pounds per gallon, the total mass of raw material that would need to . 00, 00, 00, 00 Encyclopedia of Physical Science and Technology EN002C-64 May 19, 2001 20:39 Table of Contents (Subject Area: Biotechnology) Article Authors Pages in the Encyclopedia . Revised Pages Encyclopedia of Physical Science and Technology EN002C-60 May 17, 2001 20:23 160 Biomass Utilization, Limits of essential nutrients. This is the largest number and pro- portion of malnourished. and P1: FJU Revised Pages Encyclopedia of Physical Science and Technology EN002C-60 May 17, 2001 20:23 Biomass Utilization, Limits of 163 TABLE III Energy Inputs and Costs of Corn Production per Hectare

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