bioprocess engineering principles

[...]... expected to work at the interface of biology and engineering science This textbook on bioprocess engineering is designed to prepare you for this challenge 2 Introduction to Engineering Calculations Calculations used in bioprocess engineering require a systematic approach with well-defined methods and rules Conventions and definitions which form the backbone of engineering analysis arepresented in this chapter... control, and efficient and safe layout of fermentation factories The subject of this book, bioprocessengineering, is the study of engineering principles applied to processes involving cell or enzyme catalysts I.I Steps in Bioprocess Development: A Typical New Product From Recombinant DNA The interdisciplinary nature of bioprocessing is evident if we look at the stages of development required for a complete... Given the importance of interaction between biology and engineering in bioprocessing, these differences in outlook between engineers and biologists must be overcome Although it is unrealistic to expect all biotechnologists to undertake full engineering training, there are many advantages in understanding the practical principles of bioprocess engineering if not the full theoretical detail The principal... little attempt to teach biotechnologists even those qualitative aspects of engineering applicable to process design The primary aim of this book is to present the principles of bioprocess engineering in a way that is accessible to biological scientists It does not seek to make biologists into bioprocess engineers, but to expose them to engineering concepts and ways of thinking The material included in the... this book is to teach scientists trained in biology those aspects of engineering science which are relevant to bioprocessing An adequate background in biology is assumed At the end of this study, you will have gained a heightened appreciation for bioprocess engineering You will be able to communicate on a professional level with bioprocess engineers and know how to analyse and critically evaluate new... chemistry and medical science While several excellent texts on bioprocess engineering are currently available, these generally assume the reader already has engineering training On the other hand, standard chemical -engineering environmental expression, protein translated by a texts do not revolutionary new often consider examples from bioprocessing and are written almost exclusively with the petroleum... disciplines is involved in bioprocessing Scientists working in this area are constantly confronted with biological, chemical, physical, engineering and sometimes medical questions 1.2 A Quantitative Approach The biological characteristics of cells and enzymes often impose constraints on bioprocessing; knowledge of them is therefore an important prerequisite for rational engineering design For instance,... laboratory, bringing modern biotechnology to industrial fruition requires engineering skills and know-how Biological systems can be complex and difficult to control; nevertheless, they obey the laws of chemistry and physics and are therefore amenable to engineering analysis Substantial engineering input is essential in many aspects of bioprocessing, including design and operation of bioreactors, sterilisers... standard chemicalengineering texts The chapters are organised around broad engineering subdisciplines such as mass and energy balances, fluid dynamics, transport phenomena and reaction theory, rather than around particular applications ofbioprocessing That the same fundamental engineering principle can be readily applied to a variety of bioprocess industries is illustrated in the worked examples and problems... fractionation In terms of bioprocess development, parameters of major importance are stability of the constructed strains and level of expression of the desired product After cloning, the growth and production characteristics of I Bioprocess Development: An Interdisciplinary Challenge Table 1.1 4 Major products of biological processing (Adaptedj~om M.L Shuler, 1987, Bioprocess engineering In: Encyclopedia . class="bi x0 y0 w0 h0" alt="" Biop.rocess Engineering Principles This Page Intentionally Left Blank Pauline M. Doran Bioprocess Engineering Principles ACADEMIC PRESS Har~~114rt Br.ace. present the principles of bioprocess engineering in a way that is accessible to biological scientists. It does not seek to make biologists into bioprocess engineers, but to expose them to engineering. excel- lent texts on bioprocess engineering are currently available, these generally assume the reader already has engineering training. On the other hand, standard chemical -engineering texts