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[...]... general overview of the field ofmovement 1 2 Chou et al disorders surgery, including a brief summary of basal ganglia structure and function, as well as discussions of the major surgical treatments available for PD, essential tremor (ET), other tremor disorders, dystonia, and spasticity 2 PATHOPHYSIOLOGY OFMOVEMENTDISORDERS All movementdisorders are believed to result from abnormalities of the basal... review of the surgical treatments currently available for various movement disorders, with an emphasis on surgical indications and results of surgery It should be of utmost interest to practitioners and trainees in the clinical neurosciences (neurology/neurosurgery) who want a better understanding of candidates for movement disorder surgery, the current surgical procedures, the effected results of surgery,... severity of symptoms and improve the quality of life for patients with these devastating neurological disorders Surgery for the field ofmovementdisorders has evolved significantly since Spiegel et al first described stereotaxis in 1947 (1) Much of this progress has been made within the last decade with the development of techniques for precise targeting of brain structures and the discovery of new targets... MovementDisorders Center, Pennsylvania Hospital, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A 1 INTRODUCTION From Parkinson’s disease (PD) to dystonia, movementdisorders are major neurologic causes of disability, causing not only physical handicap, but often social embarrassment as well Although a plethora of pharmacologic options exists to treat these disorders, ... Department of Neurology, University of California, San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, California, U.S.A Ali R Rezai Department of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, U.S.A Joshua M Rosenow Department of Neurosurgery, Feinberg School of Medicine of Northwestern University, Chicago, Illinois, U.S.A Uzma Samadani Department of. ..Preface Movementdisorders represent major causes of neurological disability and eventual mortality affecting millions of people across the globe From Parkinson’s disease to spasticity, these neurological disorders devastate young and old worldwide While progress continues to be made toward effective treatment, many limitations remain The combination of the limitation of medical therapy and surgical. .. Department of Neurosurgery, University of Minnesota, Minneapolis, Minnesota, U.S.A xv 1 Overview Kelvin L Chou Department of Clinical Neurosciences, Brown University Medical School, Providence, Rhode Island, U.S.A Gordon H Baltuch Department of Neurosurgery, Penn Neurological Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A Matthew B Stern Parkinson’s Disease and Movement. .. rate of these procedures Our goal was to summarize the current status of the field as well as make projections for the next few years Gordon H Baltuch Matthew B Stern v Contents Preface v Contributors xiii 1 Overview 1 Kelvin L Chou, Gordon H Baltuch, and Matthew B Stern 1 Introduction 1 2 Pathophysiology ofMovementDisorders 2 3 Surgical Treatment of. .. Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A ´ ´ Frederic Schils Department of Neurosurgery, University of Geneva, Geneva, Switzerland Jason M Schwalb Division of Neurosurgery, Toronto Western Hospital, University of Toronto and University Health Network, Toronto, Ontario, Canada Tanya Simuni Department of Neurology, Feinberg School of Medicine, Northwestern University,... Philip A Starr Department of Neurosurgery, University of California, San Francisco and San Francisco Veterans Affairs Medical Center, San Francisco, California, U.S.A Contributors Matthew B Stern Parkinson’s Disease and MovementDisorders Center, Pennsylvania Hospital, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U.S.A Atsushi Umemura Department of Neurosurgery, Nagoya . h0" alt="" Surgical Management of Movement Disorders NDT_half-series-title 6/24/05 12:31 PM Page A NEUROLOGICAL DISEASE AND THERAPY Advisory Board Louis R. Caplan, M.D. Professor of Neurology Harvard. Washington Kapil Sethi, M.D. Professor of Neurology Director, Movement Disorders Program Medical College of Georgia Augusta, Georgia Mark Tuszynski, M.D., Ph.D. Associate Professor of Neurosciences Director,. and Peter M. Rothwell 73. Gait Disorders: Evaluation and Management, edited by Jeffrey M. Hausdorff and Neil B. Alexander 74. Surgical Management of Movement Disorders, edited by Gordon H. Baltuch