Part 1 of ebook Transfusion management of the obstetrical patient: A clinical casebook provide readers with content about: obstetrical management of postpartum hemorrhage; laboratory testing and predictors of severe postpartum hemorrhage; component therapy in obstetric hemorrhage; evidence for 1:1:1 transfusion support and importance of a hemorrhage protocol; evidence for/against administration of antifibrinolytic agents during an obstetrical hemorrhage;...
Theresa Nester Editor Transfusion Management of the Obstetrical Patient A Clinical Casebook 123 Transfusion Management of the Obstetrical Patient Theresa Nester Editor Transfusion Management of the Obstetrical Patient A Clinical Casebook Editor Theresa Nester University of Washington Medical Center Bloodworks Northwest Seattle Washington USA ISBN 978-3-319-77139-7 ISBN 978-3-319-77140-3 (eBook) https://doi.org/10.1007/978-3-319-77140-3 Library of Congress Control Number: 2018942631 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed The use of general descriptive names, registered names, trademarks, service marks, etc in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland To the families who have lost a mother, wife, daughter, or sister to postpartum hemorrhage or other complications of pregnancy We hope that our energy directed toward making this a “never” event reaches you and helps you to heal Preface This series of case sections has been assembled to help educate clinicians and laboratorians so that they may better understand transfusion and therapeutic apheresis support of obstetrical patients A main focus is on management of a patient experiencing postpartum hemorrhage, both in terms of tools available to the obstetrician and the anesthesiologist and in terms of blood component therapy and laboratory testing that should be used to monitor such a patient Several sections cover basic transfusion medicine theory, so that the principles of safe transfusion practice are shared Smaller yet very important topics include prevention of sensitization to RhD in an RhD negative woman and the differentiation of causes for microangiopathic hemolytic anemia in pregnancy Case examples of red cell antibodies found on prenatal testing, and subsequent management, are also presented An overarching goal is to highlight situations where transfusion medicine consultation may help contribute to optimal patient care The authors have done an excellent job covering the topics at hand Yet, it is an incomplete work, in that large numbers of prospective, randomized clinical trials are often not available to help guide the management of these patients Where evidence is available, it is cited Beyond that is the compilation of knowledge gained by in-depth experience vii viii Preface We hope that the information presented helps to reduce the morbidity and mortality that can result from complications associated with pregnancy Seattle, WA Theresa Nester Contents 1 Obstetrical Management of Postpartum Hemorrhage Michael Dombrowski and Michael Paidas 2 Laboratory Testing and Predictors of Severe Postpartum Hemorrhage 15 Evelyn Lockhart 3 Component Therapy in Obstetric Hemorrhage 23 Joseph Griggs 4 Evidence for 1:1:1 Transfusion Support and Importance of a Hemorrhage Protocol 39 Mark Fung and Sarah Harm 5 Evidence for/Against Administration of Antifibrinolytic Agents During an Obstetrical Hemorrhage 47 Kerry L O’Brien 6 Evidence for/Against Administration of Fibrinogen Concentrate and Coagulation Factor Concentrate During an Obstetrical Hemorrhage 55 Michael Dombrowski and Michael Paidas 7 Recommendations on Blood Recovery in Obstetrics 67 Gerhardt Konig ix x Contents 8 Thrombocytopenia in Pregnancy 73 Thomas G DeLoughery 9 Von Willebrand Disease in Pregnancy Thomas G DeLoughery 81 10 Platelet Count and Neuraxial Anesthesia Cathleen Peterson-Layne and Beth R Burton 91 11 ABO Compatibility Theresa Nester 97 12 RhD Compatibility 103 Jessica Poisson 13 Other Rh Antibodies That Can Impact Transfusion 107 Jessica Poisson 14 Importance of Getting a Sample for ABO Type Early in a Resuscitation 113 Ashok Nambiar 15 Risks of Giving Uncrossmatched Red Cells 121 Ashok Nambiar 16 Management of Thrombotic Microangiopathies in Pregnancy 131 Jeffrey L Winters, Vesna D Garovic, Layana Alrahmani, and Kristina A Davis 17 Hyperhemolysis Syndrome in a Pregnant Woman with Sickle Cell Anemia 155 Henry Hilt and Oyebimpe Adesina 18 Fetal and Neonatal Alloimmune Thrombocytopenia 163 Justin Juskewitch and Jeffrey L Winters Contents xi 19 Weak D in Pregnancy 179 Meghan Delaney 20 Testing Algorithm for Rh Immune Globulin Dosing in the Post-natal RhD-Negative Mother 187 Theresa Nester 21 Pre-transfusion Testing in Women with High Bleeding Risk Requiring Prolonged Hospitalization 193 Theresa Nester and Katherine L Eastwood 22 Warm Autoantibodies During Pregnancy 201 Chakri Gavva 23 Hemolytic Disease of the Fetus and Newborn/Selection of Red Cells for Intrauterine Transfusion 207 Brian Gorospe and Nabiha Huq Saifee 24 Maternal Red Cell Alloantibody Directed Against a High Incidence Antigen 217 Theresa Nester Index 223 .. .Transfusion Management of the Obstetrical Patient Theresa Nester Editor Transfusion Management of the Obstetrical Patient A Clinical Casebook Editor Theresa Nester University of Washington... AG, part of Springer Nature 2 018 T Nester (ed.), Transfusion Management of the Obstetrical Patient, https://doi.org /10 .10 07/97 8-3 - 31 9-7 714 0-3 _1 M Dombrowski and M Paidas Risks of the high-risk... vaginal or cesarean delivery In the United States, the Bakri, BT-Cath, and Ebb balloons are commercially available, FDA-approved options Each balloon has a drainage port located in the fundal