1282 In Vivo Imaging of Rabbit Corneal Wound Healing Fibroblasts Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society of Gene TherapyS418 ����������!�����!�"���7[.]
!!"7" "!"! 1280 Insulator Elements Confer High Level, Position Independent, Copy Number Dependent, Uniform Expression of a Linked T ransgene Directed by the Transgene Erythroid Band (AE1) Promoter in Mice 1281 Successful Generation of Reporter System for Non-Invasive Imaging of the TGF β Signal T ransduction TGFβ Transduction Pathway Activity with Positron Emission T omography In Tomography Vivo Patrick G Gallagher,1 Tiffany F Frazar,2 Nancy E Seidel,2 Amanda P Cline,2 Lisa J Garrett,2 Gary Felsenfeld,3 David M Bodine.2 Pediatrics, Yale University School of Medicine, New Haven, CT, United States; 2NHGRI, NIH, Bethesda, MD, United States; NIDDK, NIH, Bethesda, MD, United States Inna Serganova,1 Vladimir Ponomarev,1 Mikhail Doubrovin,1 Ludmila Ageeva,1 Tatiana Beresten,1 Suren Soghomonian,1 Ronald G Blasberg,1 Joan Massague,2 Juri Gelovani Tjuvajev.1 Neurology, MSKCC, New York, NY, United States; 2Cell Biology Program, MSKCC, New York, NY, United States " γ" 3 β" -L,9H/ " " " 3 G '>8 '>8 "8;=:J,, "=&;J,, ' γ" & ' "8;=: J,, '>8 %γ" " 3 -,%: 3 / 3 - / @*' '>8%γ" 3 L89H α" @*' 3 3 ;H 59H γ" "=&; J,, '>8 %γ" " 3 -=%89 3 / '>8%γ" @*' 3 L;&H α" @*' @*' >3 3 @ 1 "8;=: "=&; 3 3 " - $ ,99,I 8B7,;8",::/ β" G β" &′ =′ "8;=:J,,'>8 %γ" " 3 '>8%γ" " -B%B 3 / -O9998/ 3 '>8%γ" 3 L,9H α" @*' >3 -899H 3 / B '>8 1 "8;=: 7 8/ '>8 " " 3 γ" β" -L,9H/I ,/ % 3 56+)7 @ G " 3 ?β ?β " " ?β% A?! )7 $ - 1 α / α"( "'#D" A?! '#D8 ( $*' '#D8 ( C(.8% ?! " * 69 #$'"#2" ,=8 " ?β% A?! ( 68: #$'"#2" ,=8 α"( "'#D" A?! 3 ?"β 6: A?! 3 1 ?'( -86" ?'4 =C" @/ )*)7 ' ?β 8B 3 ?β8 -,%/ ?"β8 3 A?! ?'( -T89, / ( ?'4% @ -989±99,/ " -999;±99998/ (*)+()7 ?'4 α"( "'#D" A?! ?β 8,6"?'4 !> " ?β S418 1282 In Vivo Imaging of Rabbit Corneal Wound Healing Fibroblasts Joel Gatlin, Michael Melkus, Angela Padgett, J Victor Garcia, James V Jester 0 G ' @$886 #D." 3 ?! G ?'( - / 3 E 3 3 3 ! - 65H ?!J #) =/( 1 ?! 3 C 1 "$ 3 " #D. Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy !!"7" "!"! ) 1 " ?!" " 1283 Critical Role of Putative MyoD and MEF-2 Binding Sites in the Construction of a Powerful MYH 3-Based Muscle-Specific T ranscriptional Cassette Transcriptional Stephane M Konig,1 James M Burkman,1 Hansell H Stedman.1 Surgery, University of Pennsylvania Medical Center, Philadelphia, PA, United States "' &V -#+C =/ 3 ' - >*>('* ! ! * * "**!! ! !"!!#'A>@ $*'" 2 2 ' "22' > ( ( " >((/ 3 #+C C # " #+C = &V" &V #+C = #$ #>?, -#$ #>?", G " / ' 4 -699 / 3 3 -,9 / 3 (.69 ? G " #$ #>?, # ++8- / 1 3 1 3 #>?", #+C = 3 1284 Effects of Distance on the Activity of the Chicken HS4 Chromatin Insulator in Oncoretrovirus Vectors Mari Aker,1 Julie Tubb,1 George Stamatoyannopoulos,1 David W Emery.1 Department of Medicine, University of Washington, Seattle, WA, United States 3 ' 1 3 8, $* " 6 β" -C(6/ #(. " 3 Q!*'( 5;758&9 ,999R #!*, 3 7 ?! D @ -D @→?!/ * ! -!→* / @ C(6 D @ Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ! C D @ 8, C(6 5&9 D @ 4= D @ 8, C(6 3 4= C(6 C(6 8, C(6 8/ ,&9 E ,/ &59 G -N / =/ C(6 E N 89 & 89 B % *C= = * " -=& &, / G 3 D @→?! 0 3 ?! &5 ±=8H N 3 ?! B9 ±=8H N 3 ,&9 C(6 3 ?! 6; ±=5H ,&9 N 3 ?! 65 ±=6H 8, C(6 3 ?! :8 ±,,H -M9998 / ,&9 C(6 8, &59 ? 1285 Renal Cell Carcinoma-Specific Oncolysis Mediated by MN-Promoter Based T ranscriptional Transcriptional Regulation of Adenoviral E1a Protein Thomas A Gardner,1 David W Brandli, Malka Shalhav,1 Tenir Shalhav,1 Hong-Sup Kim,1 Chinghia Kao.1 Dept of Urology, Microbiology and Immunology, Walther Oncology Center, Indiana University Medical Center, Indianapolis, IN, United States " ! #* -@/ #* @" #* #* ' '3 D= @ " @ @ ' "#*">8">8 ' " >8"#*">8 G #* >8 >8 #* C @ (A"@",5(A"@"=:(A"@"6,(A"@"&, (A" @"&6 " (A"@",5 (A" @"6, #*-"/ #*-J/( @ 2'D2% E ' "#*">8 " #." #* @ @ "!@ #*" #*-J/ @ #*-"/ @ " ' "#*" >8">8 ' ">8"#*">8 #*-J/ @ #*-"/ @ "@ ' "#*">8 E " #*-J/ @ ? @ @ S419