1237 Analysis of Gene Transfer to Lymphoid Cell Populations Following In Utero Administration of Lentiviral Vectors to Fetal Rhesus Monkeys Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts C[.]
*4 >@) >*> @'*(?>@ 1235 Hematopoietic Stem Cell Directed Gene Transfer: Effect of Pseudotyping in In-Utero Gene Therapy Amrithraj M Nair,2 Hajime Hiraragi,2 John O′Rourke,1 Bruce A Bunnell.1 Molecular Medicine, Children′s Hospital, Columbus, Ohio, United States; 2Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States ? ) " " -C(/ 3 -#D./ C( " E ' D - 'D./ ' #D. @ -@$886/ @ β" -DN/ #D. 3 'D. @ @$886 E " 8B =389& ? 8 = -?4" #/ -2?4">/ G β" !@ !@ #D. E @$886 B,&±B,&H B,&±::=H ' E 'D. 6=;&±::=H DN E 8,&±;,,H E E ;=B6±8&;H @$886 'D. ;88:±8&9,H 6B;5±:=BH 885±5,8H @$886 E &8=6±8&=5H 'D. -=55=±89BH =::5±685H 885±8&:H / C( E #D. ! @$886 'D. @$886 'D. " 1236 Gestational Age Determines Gene T ransfer Transfer Efficienty to Hematopoietic Cells, Lung and Liver Following In Utero Retroviral-Mediated Gene T ransfer Transfer Christopher D Porada,1 Paul Park,1,2 Alireza Torabi,1,2 Graỗa Almeida-Porada,1 Esmail D Zanjani.1,2 Animal Biotechnology, University of Nevada, Reno, Reno, Nevada, United States; 2Medicine, VA Sierra Nevada Health Care System, Reno, Nevada, United States E " S402 " 3 3 " #(." -@?!/ &6&;B& ;: - 786& / -!2/ -2#/ " E 8,9 3 " % 3 @?! 89" 3 &; 3 @?!J !2 2# B& ;: !2 2# E &; 3 3 @?! E B& ;: G -89" / C 3 " 0 E 3 ' " E " E % 3 1237 Analysis of Gene T ransfer to L ymphoid Cell Transfer Lymphoid Populations Following In Utero Administration of Lentiviral V ectors to Fetal Rhesus Monkeys Vectors Chang I Lee,1 Bruce A Bunnell,2 Donald B Kohn,3 Alice F Tarantal.1 California Regional Primate Research Center, University of California, Davis, CA, United States; 2Pediatrics, Children′s Research Institute, Columbus, HO, United States; 3Research Immunology/BMT, Childrens Hospital Los Angeles, LA, CA, United States ? ? -8/ " -,/ 3 -=/ 1 C 1 -'$'/ 1 -'$(/ 3 2 3 (* (." Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy " # " C."8" #*$ -89;"89: % / 3 -> ?!/ 3 &9 - 8B&±89 / B B 2 $, $6 $: $85 = -; " / !@ > ?! !@ 8 > ?! 89& - 8 899999 / ' ' $*'" > ?! ' $, $6 $: $85 C 3 .(." C."8" ( 3 !"" # " 1238 Optimising Retroviral-Mediated Gene T ransfer Transfer into Hematopoietic Stem Cells under Clinical Relevant Conditions Sonja Naundorf,1 Stephanie Laufs,2 Axel A Fauser,1 Hans-Georg Eckert,1 W Jens Zeller,2 Stefan Fruehauf,3 Klaus Kuehlcke.1 European Institute for Research and Development of Transplantation Strategies (EUFETS AG), Idar-Oberstein, Germany; 2German Cancer Research Center (DKFZ), Heidelberg, Germany; 3Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany @ -( G ,999/ $=6J @ ®-@*/ - / " -A ,99,/ @* ' G D= DB ' 8 -#$@8/ $*' *)$%($ @ 8,= 3 1 !@ ) @* 89 % " 3 " ' *)$%($ = % " 3 " *)$% ($ ? " @* % " 3 " ( " @* D= DB Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy ( S !@ 3 D= DB ) " ' 3 1239 The Selective Amplifier Gene Promotes Multiclonal Expansion of Hematopoietic Stem/Progenitor Cells in a Nonhuman Primate Masaaki Takatoku,1 Yutaka Hanazono,2 Takeyuki Nagashima,3 Hiroaki Shibata,4 Naohide Ageyama,4 Yasuji Ueda,3 Akihiro Kume,2 Cynthia E Dunbar,5 Keiji Terao,4 Mamoru Hasegawa,3 Keiya Ozawa.1,2 Division of Hematology, Department of Medicine, Jichi Medical School; 2Division of Genetic Therapeutics, Center of Molecular Medicine, Jichi Medical School; 3DNAVEC Res Inc.; 4Tsukuba Primate Center, National Institute of Infectious Disease; Hematology Branch, NHLBI, NIH 3 " -C(/ C( -(' / "(? - 3 / " (' 3 3 -A 2 855;I597=::6# A# 8555IB789=:F @