217 Enhanced Intramuscular Gene Expression by DNA Delivery Via Combined Polymeric Networks / Electroporation Molecular Therapy Vol 5, No 5, May 2002, Part 2 of 2 Parts Copyright © The American Society[.]
!"" # 215 Use of Southern Hybridisation T o Analyse To Plasmid V ector Structure in the Mouse Lung Airways Vector Ian A Pringle,1,4 Sundhya Raman,2 Seng H Cheng,3 Deborah R Gill,1,4 Stephen C Hyde.1,4 GeneMedicine Research Group, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom; 2ATR-X Research Group, Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom; 3Genzyme Corporation, Framingham, MA, United States; 4The United Kingdom Cystic Fibrosis Gene Therapy Consortium, United Kingdom " 3 $*' -$*'/ ( $*' ' " 3 $*' AD 3 #. " (.69 ? 3 3 , -56&8 J%",;,9 @D4% / ; ( ($ 3 3 ! AD 3) , >6)@?= " 3 D 3 8, AD 3) -L89H , AD 3 :6/ 42D 3 3 1 " 3 AD 3 " 3 " 4 ( $*' 3 $*' 2'D2% $*' : D B; -BBμ $*'%9&# *1; 899μ/ # , ; $*' -,99 % : / E $*'" G # " G (>'! 3 (>'! % * (>'! 3 89 ,9 218 Biodistribution and In V ivo Gene T ransfer of Vivo Transfer Liposomes Generated from Poly(Cationic Lipid) and DOT AP DOTAP Li Liu,1 Mark A Zern,1 Michael H Nantz,2 Jian Wu.1 Transplant Research Institute, University of California, Davis Medical Center, Sacramento, CA, United States; 2Department of Chemistry, University of California-Davis, Davis, CA, United States &'( 7 8," - 3/" ="- / -$) '!/ - / -$) '!" / - / -!D/ 3 " -2E ,998I 8,7,&8",&;/ !D" $) '!" $) '!"$)!> )7 7 !D" $) '!" $) '!" $)!> =78 Q=CR" =9 E 3 $*' E - =/ E D ,6 )*)7 =9 E Q=CR" " !D" E $) '!" $) '!"$)!>-=&B±6; :589±&9BI;=69±6,8O998M =/ !D" $) '!" $) '!"$)!> E $) '!" $) '!"$)!> ,," ,=" !D" "E D !D" "E E $) '!" $) '!"$)!> -=B,&±B;& 8B6&±68:I 885=±,8& % 899 O99&/ D -,& =;" / !D" "$*' E = E $) '!" "$*' $) '!"$)!>"$*'-65,58=±=&=B6 85B=,8±::9& 8=,6;,±66:&6 @D4% O998 M =/ (*)+(7 ) G " $) '!" $) '!"$)!># !D" $) '!" $) '!"$)!> = E !D" $) '!" $) '!"$)!> 219 Increasing the Therapeutic Index of Cationic Lipid:pDNA Complexes Using Dexamethasone Jennifer D Tousignant,1 Simon J Eastman,1 Steven Boule,1 Macy Joseph,1 Rebecca Rubenstein,1 Stephen A Rydberg,1 Qiuming Chu,1 Ronald K Scheule.1 Genzyme Corporation, Framingham, MA, United States ( 7 $*'-$*'/ 3 " 3 G Molecular Therapy Vol 5, No 5, May 2002, Part of Parts Copyright © The American Society of Gene Therapy 3 " 3 1 N2 ( 3 7$*' 3 ? " 1 3 3 7$*' ) 3 3 3 $ 3 " $ 3 3 &"89 G 3 #. 41 2 3 " ' 3 3 1 3 ? 7$*' " E 3 3 ? ′ 220 Development of a Dual-Luciferase Fusion Gene as a Sensitive Marker for Site-Directed DNA Repair Strategies Michael L Bennett,1 Jerome Schaack.1 Microbiology, University of Colorado Health Sciences Center, Denver, Colorado, United States @ 1 " $*' 69H 4 G 1 C G " G 3 3 > " $*' 1 " 1 &9F89"B-O8 ,99999/ 221 Sustained High Levels of Gene Expression Achieved In-Vivo by Electroporation of DNA-Containing Microparticles D Wang, K Roy, M L Hedley, S P Barman Zycos Inc, Lexington, MA, United States G $*' G S73