Handbook of Medicinal Herbs 663 MAD); Eczema (f; CEB); Emphysema (f; MAD); Enuresis (f; MAD); Fever (f; APA; FAD; FEL; TOM); Hemorrhoid (f; CEB); Hoarseness (f; FEL); Inflammation (1; APA; DEM); Laryngosis (f; MAD); Mucososis (f; TOM); Ophthalmia (f; MAD); Pain (1; FAD); Pertussis (f; MAD; TOM); Pharyngosis (1; CAN); Photophobia (f; MAD); Phthisis (f; MAD); Pleurisy (f; APA; FAD; MAD); Pneumonia (f; FAD; FEL; MAD; TOM); Pulmonosis (f; MAD); Respirosis (2; DEM; FAD; KOM; PH2; PIP); Rheumatism (1; DEM; FAD; MAD; TOM); Smallpox (f; TOM); Snakebite (f; APA; CEB; TOM); Sore Throat (f; FEL); Swelling (f; FAD); Syphilis (f; CEB); Toothache (f; DEM); Tracheosis (1; PHR; PH2); Tuberculosis (f; MAD); Typhoid (f; FEL); Water Retention (f; FAD; FEL); Wound (f; FEL) Dosages (Senega Root) — Root ×/day (AHP; KOM); 0.5–2 g root, several ×/day (MAD); 1.5–3 g root (PIP); 0.5 g (ca 1/5 tsp) root/cup tea/day, not to exceed g/day (APA); 0.5 g root/cup (HHB); 0.5–1.0 g dry root, or in tea, ×/day (CAN); 0.5–1 g powdered root (PNC); 2.5–5 ml concentrated root tea (PNC); 0.3–1 ml liquid root extract (CAN; PNC); 1.5–3 g fluid root extract (KOM; PIP); 2.5–7.5 g root tincture (KOM; PIP); 2.5–5 ml root tincture (CAN; PNC) Contraindications, Interactions, and Side Effects (Senega Root) — Class 2b Emmenagogue and uterotonic Contraindicated in gastric ulcers and gastrosis; not for long-term use (AHP) Commission E reports root permitted for oral use No contraindications, adverse effects, or interactions, except for GI irritation from continued or prolonged use (AEH; KOM) The Herbal HDR cautions that overdosage leads to diarrhea, gastric complaints, nausea, and queasiness (PHR) CAN cautions that saponins can irritate GI tract Polygalic acid and senegin irritate the GI mucosa and may cause a reflex secretion of mucus in the bronchioles Large doses may cause purging and vomiting (CAN) Extracts (Senega Root) — One antiinflammatory triterpenic acid is useful for eczema, graft rejection, multiple sclerosis, and psoriasis, according to a French patent mentioned by CAN Looking at that suggests, to me, that the acid has immunosuppressant activity, which would be contraindicated in most diseases Saponins can be hemolytic and a GI irritant (CAN) Hemolytic saponins are toxic when injected iv, but have low toxicity when given orally since they don’t cross GI mucosa (CAN) Free saponins in GI tract may react with mucosa, causing an increased permeability of small intestine to intraluminal solutes and inhibiting active nutrient absorption This activity may facilitate entry of antigens and active food peptides into the blood circulation with adverse (and I also suppose good) side effects (CAN) SENSITIVE PLANT (Mimosa pudica L.) ++ Activities (Sensitive Plant) — Abortifacient (f; JFM); Analgesic (f; AAB); Antibacterial (1; AAB); Antiinflammatory (1; AAB); Antipyretic (f; JFM); Antispasmodic (1; AAB); Antiviral (1; AAB); Depurative (f; KAB); Diaphoretic (f; KAB); Diuretic (f; AAB; JFM); Emetic (f; JFM); Myorelaxant (f; AAB); Sedative (f; AAB); Tonic (f; KAB); Vermifuge (f; ZUL) Indications (Sensitive Plant) — Adenopathy (f; JLH); Asthma (f; KAB); Backache (f; AAB); Bacteria (1; AAB); Biliousness (f; KAB); Calculus (f; KAB); Cancer (f; KAB); Conjunctivosis (f; KAB); Convulsion (f; KAB; ZUL); Cramp (1; AAB); Dysmenorrhea (f; ZUL); Dysuria (f; JFM; WOI); Eczema (f; JFM); Edema (f; KAB); Fatigue (f; KAB); Fever (f; JFM; KAB); Fistula (f; KAB); Gravel (f; WOI); Guinea Worm (f; KAB); Hemorrhoid (f; KAB; WOI); Hydrocele (f; KAB); Infection (1; AAB); Inflammation (1; AAB; KAB); Insomnia (f; AAB; ZUL); Jaundice (f; KAB); Leprosy (f; KAB); Leukoderma (f; KAB); Lumbago (f; JFM); Myalgia (f; KAB); Nephrosis (f; JFM); Nervousness (f; AAB; ZUL); Pain (f; AAB; KAB); Palpitation (f; ZUL); Rheumatism (f; KAB); Scrofula (f; KAB); Sinusosis (f; WOI); Smallpox (f; KAB); Snakebite (f; KAB); Sore (f; WOI); Staphylococcus (1; AAB); Sting (f; KAB); Teething (f; ZUL); Tumor (f; JLH); Ulcer (f; KAB); Uterosis (f; KAB); Vaginosis (f; KAB); Virus (1; AAB); Water Retention (f; AAB; JFM); Worm (f; ZUL) S 664 Handbook of Medicinal Herbs Extracts (Sensitive Plant) — Contains “epinephrine adrenalin” (AAB) and mimosine (WBB; ZUL) SERVICETREE (Sorbus domestica L.) ++ Synonym: Pyrus domestica (L.) Sm., P sorbus Gaertn “Sorb Apple” in PH2 Activities (Servicetree) — Analgesic (1; PH2); Antiinflammatory (1; PH2); Astringent (1; EFS; PH2); Dermabrasive (f; PH2) Indications (Servicetree) — Inflammation (1; PH2); Pain (1; PH2) SESAME (Sesamum indicum L.) +++ Synonyms: S mulayanum N C Nair, S orientale L S Activities (Sesame) — Abortifacient (f; EFS; FEL; KAB); Antiabortive (f; JFM); Antiedemic (f; JFM); Anticonvulsant (f; DAA); Antiinflammatory (f; JFM); Antioxidant (f; WOI); Aphrodisiac (f; KAB; WOI); Astringent (f; KAB); Demulcent (f; EFS; FEL; KAB); Dentifrice (f; DAA); Diuretic (f; KAB; SKJ; WOI); Emmenagogue (f; EFS; FEL; KAB; SKJ; WOI); Emollient (f; KAB; SKJ; WOI); Immunosuppressant (1; HH2; PH2); Lactagogue (f; JFM; KAB; SKJ; WOI); Laxative (f; JFM; PH2); Neurotonic (f; JFM); Propecic (f; DAA; KAB); Tonic (f; KAB; SKJ; WOI) Indications (Sesame) — Alopecia (f; DAA; JFM); Amenorrhea (f; FEL; KAP; WOI); Arthrosis (f; JFM; KAB); Asthma (f; KAB); Bleeding (f; KAB); Bronchosis (f; JFM); Burn (f; KAB; WOI); Cachexia (f; DAA); Cacoethes (f; JLH); Cancer (f; JLH); Cancer, abdomen (f; JLH); Cancer, breast (f; JLH); Cancer, colon (f; JLH); Cancer, eye (f; JLH); Cancer, stomach (f; JLH); Catarrh (f; FEL; JFM; KAP); Cholera (f; KAP); Cold (f; DAA; JFM); Condylomata (f; DAA); Conjunctivosis (f; JFM); Constipation (f; DAA; JFM; KAB; PH2); Convulsion (f; DAA); Cough (f; KAB; WOI); Cystosis (f; FEL; KAP); Dermatosis (f; FEL; JFM; PH2); Diarrhea (f; FEL; JFM); Dyschezia (f; PH2); Dysentery (f; FEL; KAB; SKJ); Dysmenorrhea (f; DAA; KAP; WOI); Dysuria (f; KAB; SKJ); Edema (f; JFM); Enterosis (f; JLH; KAP); Gastrosis (f; JLH); Gout (f; KAB); Gray Hair (f; DAA; KAB); Hemorrhoid (f; DAA; KAB; SKJ; WOI); High Blood Pressure (f; DAA); Impotence (f; DAA); Induration (f; JLH); Inflammation (f; JFM; KAB); Malaria (f; KAB); Mastosis (f; JLH); Menorrhagia (f; KAB); Migraine (f; KAB); Nephrosis (f; FEL); Handbook of Medicinal Herbs 665 Neurosis (f; DAA); Neuroparalysis (f; DAA); Ophthalmia (f; FEL; JLH); Otorrhea (f; DAA); Proctorrhagia (f; WOI); Pulmonosis (f; KAB); Respirosis (f; KAB); Rheumatism (f; JFM; PH2); Scab (f; PH2); Scabies (f; KAB); Smallpox (f; KAB); Snakebite (f; KAB); Sore (f; DAA; SKJ; WOI); Sore Throat (f; KAB); Splenosis (f; KAB); Strangury (f; KAB; KAP); Swelling (f; JFM; PH2); Syphilis (f; KAB); Urethrosis (f; FEL); Uterosis (f; DAA); Uterorrhagia (f; JFM); VD (f; KAB); Vertigo (f; DAA; KAB); Wart (f; DAA; JLH); Water Retention (f; KAB; SKJ; WOI) Dosages (Sesame) — 30–60 g (HH2); 20 g seed/0.5 liter water (JFM) Contraindications, Interactions, and Side Effects (Sesame) — Class (Food) (AHP) Not covered (KOM; PHR) “Health hazards not known with proper therapeutic dosages” (PH2) Some people are anaphylactically sensitive to sesame (AHP) While the seeds are rich in oil, they not contain 97% to 98% fatty oil, as reported in PH2 In vitro, sesamin is immunosuppressant, IC50 = 0.33 µg/ml, cf prednisolone 0.06 µg/ml (HH2) SHANSHI (Coriaria ruscifolia L subsp microphylla (Poir.) L E Skog) X Synonyms: C microphylla Poir., C thymifolia Humb & Bonpl ex Willd Activities (Shanshi) — Astringent (f; CRC); Candidicide (f; CRC); Hallucinogen (f; CRC); Poison (f; CRC); Rodenticide (f; CRC) Indications (Shanshi) — Candida (f; CRC); Collapse (f; CRC); Diarrhea (f; CRC); Yeast (f; CRC) Dosages (Shanshi) — mg as a stimulant in case of collapse (CRC) Contraindications, Interactions, and Side Effects (Shanshi) — “Classified as a narcotic hallucinogen (giving flight sensations) The LD50 for the leaves is 3.75 mg/kg, mature fruits 1.55, and green fruits 0.45 mg/kg Frequent symptoms of intoxication include stupor, vertigo, convulsion Death may result from asphyxia, respiratory paralysis, and heart failure.” (CRC) SHATAVARI, SHATAMULI (Asparagus racemosus Willd.) ++ Synonyms: A rigidulus Nakai, A schoberioides Kunth, Protasparagus racemosus (Willd.) Oberm Activities (Shatavari) — Alterative (f; DEP; SUW); Amebicide (1; KAP; MPI); Antiaggregant (1; MPI); Antibacterial (1; ABS; WO2); Anticancer (1; KAP; MPI); Antiinflammatory (f; KAB); Antioxytocic (1; MPI); Antipyretic (f; DEP; SUW); Antispasmodic (f; DEP; KAP; SUW); Antitussive (1; FT71:686); Aperitif (f; KAB); Aphrodisiac (f; DEP; HHB; KAP; SUW); Astringent (f; KAB); Bitter (f; KAB); Bradycardic (f; MPI); Carcinogenic (1; WO2); Demulcent (f; DEP; SUW); Depurative (f; KAB); Diuretic (f; DEP; HHB; MPI; SUW); Expectorant (f; KAB); Fungicide (1; WO2); Hypotensive (1; MPI); Lactagogue (1; MPI; SUW; WO2); Laxative (f; KAB); Mastogenic (f; MPI); Respiradepressant (1; MPI); Stimulant (f; DEP); Stomachic (f; KAB); Tonic (f; MPI); Tuberculosis (f; KAB); Uterorelaxant (1; WO2) Indications (Shatavari) — Ameba (1; KAP; MPI); Anorexia (f; KAB); Bacteria (1; ABS; WO2); Biliousness (f; KAB; KAP); Cancer (1; JLH; KAB; KAP; MPI); Cancer, abdomen (1; JLH; MPI); Cancer, colon (1; JLH; MPI); Cancer, skin (1; KAP); Cardiopathy (f; MBB); Cerebrosis (f; SUW); Constipation (f; KAB); Cough (1; FT71:686); Cramp (f; DEP; KAP; KAB; SUW); Dermatosis (f; ABS); Dehydration (f; HH2); Diabetes (f; SUW); Diarrhea (f; DEP; KAB; SUW); Dysentery (f; DEP; KAB; SUW); Dyspepsia (f; HH2); Dysuria (f; KAB); Enterosis (f; JLH); Epilepsy (f; KAB; MBB); Epistaxis (f; SKJ); Escherichia (1; WO2); Fever (f; DEP; SKJ; SUW); Fungus (1; WO2); Gastrosis (f; MBB); Gleet (f; KAB; KAP); Gonorrhea (f; KAB; KAP); Gout S 666 Handbook of Medicinal Herbs (f; MBB); Heatstroke (f; SKJ); Hematuria (f; MBB); Hemorrhoid (f; MBB); Hepatosis (f; KAB; KAP; MBB); High Blood Pressure (1; MBB; MPI); Impotence (f; DEP); Infection (1; WO2); Infertility, female (f; HHB); Inflammation (f; KAB; MBB); Leprosy (f; KAB); Mycosis (1; WO2); Nephrosis (f; KAB; KAP); Nyctalopia (f; KAB); Ophthalmia (f; KAB); Pain (f; SKJ); Pulmonosis (f; MBB); Rheumatism (f; HH2; SUW); Salmonella (1; WO2); Schistosomiasis (f; HH2); Shigella (1; WO2); Smallpox (f; DEP); Spermatorrhea (f; SKJ); Staphylococcus (1; WO2); Thirst (f; SKJ); Tuberculosis (1; PR14:118); Uterosis (f; MBB); VD (f; KAP; PR14:118); Water Retention (f; DEP; HHB; MPI; SUW) Dosages (Shatavari) — 12–20 ml infusion (KAP); 56–112 ml decoction (KAP); 20–30 g powdered herb (KAP) Extracts (Shatavari) — Methanol extracts antitussive, IC40 = 200 mg/kg orl mus, IC58.5 = 400 mg/kg orl mus Contains saponins, shatavarin I to IV Shatavarin IV is a glucoside of sarsapogenin (two molecules of rhamnose and one of glucose) At doses 20–500 µg/ml, it specifically blocks ocytocin SHAVEGRASS, GREAT SCOURING RUSH (Equisetum hyemale L.) + Activities (Shavegrass) — Abortifacient (f; DEM); Astringent (f; CRC); Depurative (f; CRC); Diaphoretic (f; CRC); Diuretic (f; CRC; DEM); Hemostat (f; CRC) Indications (Shavegrass) — Adenopathy (f; DEM); Backache (f; DEM); Bleeding (f; CRC); Cancer (f; CRC); Carcinoma (f; JLH); Cataract (f; DEM); Cholecystosis (f; CRC); Cold (f; DEM); Conjunctivosis (f; DEM); Constipation (f; DEM); Cystosis (f; CRC); Dermatosis (f; DEM); Diarrhea (f; DEM); Dysentery (f; CRC); Dysmenorrhea (f; CRC; DEM); Dysuria (f; CRC; DEM); Embolism (f; CRC); Enuresis (f; CRC); Fever (f; CRC); Fistula (f; CRC); Gonorrhea (f; DEM); Hemorrhoid (f; CRC); Incontinence (f; CRC); Lumbago (f; DEM); Nephrosis (f; DEM); Ophthalmia (f; CRC; DEM); Pain (f; DEM); Prostatosis (f; DEM); Pulmonosis (f; CRC); Sore (f; CRC); Stone (f; CRC); Syphilis (f; DEM); Tuberculosis (f; CRC); Urethrosis (f; CRC); VD (f; DEM); Water Retention (f; CRC; DEM) S Contraindications, Interactions, and Side Effects (Shavegrass) — “Classified by the FDA as an Herb of Undefined Safety: Infusion of whole plants used sometimes in dropsical and renal diseases but the diuretic action is very feeble Cattle overdosed for diuresis have voided blood Said to have caused poisoning in California Horsetails are said to develop a powerful nerve poison, aconitic acid Sheep and cattle are poisoned by grazing the fresh plant; horses, usually by eating the dried plant in hay It produces, especially when dried, sudden symptoms of weakness and loss of appetite followed, after a few weeks, by loss of muscular control, excitement, and falling, and in acute cases, labored respiration, rapid, weak pulse, diarrhea, convulsions, coma, and death” (CRC) SHEEP SORREL (Rumex acetosella L.) ++ Used interchangeably with R acetosa (HHB) Activities (Sheep Sorrel) — Allergenic (1; WOI); Antipyretic (f; EFS; FAD; KAB); Antitumor (1; FNF); Depurative (f; EFS); Diaphoretic (f; EFS; KAB; WOI); Diuretic (f; FAD; PNC; WOI); Hemostat (f; EFS); Laxative (1; APA; EFS); Peristaltic (f; APA) Indications (Sheep Sorrel) — Bleeding (f; EFS); Bruise (f; DEM); Cancer (1; FAD; FNF; WOI); Cancer, colon (1; FNF; JLH); Cancer, eye (1; FNF; JLH); Cancer, face (1; FNF; JLH); Cancer, skin (1; FNF; JLH); Cancer, stomach (1; FNF; JLH); Cancer, throat (1; FNF; JLH); Constipation Handbook of Medicinal Herbs 667 (1; APA; EFS); Dermatosis (f; EFS; JLH); Diarrhea (f; FAD); Dysmenorrhea (f; FAD); Dysuria (f; PNC); Epithelioma (1; FNF; JLH); Fever (f; EFS; FAD; KAB; WOI); Gastrosis (f; DEM); Inflammation (f; FAD); Metrorrhagia (f; FAD); Nephrosis (f; KAB); Scrofula (f; FEL); Sore (f; DEM); Syphilis (f; FEL); Tuberculosis (f; DEM); Tumor (1; FNF; FAD); Wart (f; DEM; JLH); Water Retention (f; FAD; PNC; WOI) Dosages (Sheep Sorrel) — As a food pharmaceutical, a USDA 100-g serving of fresh sorrel equates to about 10 g of dry sorrel (HOW) Contraindications, Interactions, and Side Effects (Sheep Sorrel) — Class 2d (AHP) Those with kidney stones should avoid this plant Oxalates should be avoided by patients with endometriosis and nephrosis Oxalic acid levels may attain 10–35% of dry matter in some species The LDlo reported for humans is 700 mg/kg body weight Weighing 110 kg, my LDlo would be 77,000 mg, or 77 g (more than ounces of oxalic acid) (HOW) Polysaccharides show antitumor activity (ZUL) SHEPHERD’S PURSE (Capsella bursa-pastoris (L.) Medik.) ++ S Synonym: Thlaspi bursa-pastoris L Activities (Shepherd’s Purse) — Analgesic (f; CEB); Antibacterial (f; APA); Anticapillary Fragility (1; CAN); Antihemorrhagic (f; BGB; FAD; SHT); Antiinflammatory (1; APA; BGB; PNC); Antineoplastic (1; BGB); Antipyretic (f; PNC); Antitumor (1; PNC); Antiulcer (1; BGB; PNC); Cardioactive (1; PH2); CNS Depressant (1; BGB; CAN); Diuretic (1; APA; FAD; PNC); Emmenagogue (1; AHP; CEB); Hemostat (1; APA; PNC); Hypertensive (2; KOM); Hypotensive (2; APA; BGB; KOM); Larvicide (f; CEB); Laxative (f; APA); Muscarinic (2; KOM; PIP); Myostimulant (f; BGB); Negative Chronotropic (2; BGB; KOM; PH2); Positive Inotropic (2; BGB; KOM; PH2; PIP); Oxytocic (1; APA; PNC); Rubefacient (1; CAN); Urinary Antiseptic (f; CAN); Uterocontractant (2; FAD; KOM; PH2; PIP); Vasodilator (f; BGB); Vermifuge (f; DEM) ...664 Handbook of Medicinal Herbs Extracts (Sensitive Plant) — Contains “epinephrine adrenalin” (AAB) and mimosine... KAB); Mastosis (f; JLH); Menorrhagia (f; KAB); Migraine (f; KAB); Nephrosis (f; FEL); Handbook of Medicinal Herbs 665 Neurosis (f; DAA); Neuroparalysis (f; DAA); Ophthalmia (f; FEL; JLH); Otorrhea... (1; WO2); Gastrosis (f; MBB); Gleet (f; KAB; KAP); Gonorrhea (f; KAB; KAP); Gout S 666 Handbook of Medicinal Herbs (f; MBB); Heatstroke (f; SKJ); Hematuria (f; MBB); Hemorrhoid (f; MBB); Hepatosis