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Dashboard Review Fourth Quarter of FY-2017 Joe Selby, MD, MPH Executive Director On Target Projected/Target Off Target Needs Board Attention Too Early to Evaluate / No Target Board of Governors Dashboard Fourth Quarter FY-2017 (As of 9/30/2017) $428M for FY-2017 400 60 Q1 Q2 Q3 Q4 500 100 25 Median time: 9.2 months 75 19 23 27 29 Percent Percent 75 100 36 29 36 32 50 21 25 Q1 Q2 Q3 Q4 Altmetrics 70 20 Articles 50 40 12 CER 30 Other 20 Articles 60 Number of Publications in Top 5% of Research Scored 15 10 Q1 Q2 Q3 Q4 Q1 CER Other 10 0 30 Time to Complete Peer Review (Target: months) Results Published in Literature Q2 Q3 Q4 400 Goal 2: Speeding Uptake PCORI-funded results on self75 monitoring of blood glucose 50 have been taken up into N=1 N=2 practice via UpToDate®, a 25 point-of-care, evidence-based Q1-Q2: NA Q3 Q4 medical resource software used by clinicians globally, and % Abstracts Posted to nearly 90% of major academic PCORI.org in < 90 days medical centers in the US External Funding in PCORnet Goal 3: Externally- and Co-Funded Influencing Research 10 Projects (Cumulative) PCORI is credited with inspiring policy changes and capacity building efforts at the Externally 2 Funded University of Arkansas for Medical Science (UAMS), including an IRB Co-Funded with PCORI Dissemination policy on returning results to the Q1 Q2 Q3 Q4 Impact community and participants 100 Target > 90% Q2 Q3 Q4 % of Draft Final Research Reports On Time 33 200 300 $ Millions Public Reporting of Research Findings PCORI Peer Review Completed as of Q4: 12 Target > 90% N= 100 % of Projects On Track Draft Final Research Reports 50 50 Process 200 300 $ Millions Actual 70 Goal 1: Increasing Information A PCORI-funded study comparing two programs to prevent falls among older adults found that a groupbased standing-exercise program called On The Move is more effective than commonly used seated exercises Target 100 % Uptake 100 80 Percent Total FY-17 $379M $423M for FY-2017 Outputs Actual Percent 90 Budgeted Projects Budgeted Operating Budget and Research Awards Target > 90% 100 Use Includes funds committed to PCORnet Q4 2017 Narrative Examples Budget Inputs Project Performance Funds Committed to Research Q1 2017 Q2 2017 Q3 2017 Goal 1: Results of PCORI-Funded Research Standing-exercise is more effective than seated exercise in improving mobility in older adults Brach JS, Perera S, Gilmore S, et al Effectiveness of a Timing and Coordination Group Exercise Program to Improve Mobility in Community-Dwelling Older Adults: A Randomized Clinical Trial Jama Internal Aug 2017 Study title: On the Move: Optimizing Participation in Group Exercise to Prevent Walking Difficulty in At-Risk Older Adults Exercise is beneficial to physical and mental health and may prevent walking difficulty and promote independence for community-dwelling older adults Exercise programs offered to older adults are typically a seated range-of-motion exercises that not involve walking This study compared the effectiveness of an exercise program (On the Move) that focuses on the timing and coordination of movement with usual care (a seated strength, endurance, and flexibility program) The study found that the On the Move program was more effective than the seated exercise program at improving function, disability, and walking ability of older adults • Principal Investigator: Jennifer S Brach, PhD, University of Pittsburgh at Pittsburgh ” Older adults who are interested in improving their mobility should consider participating in a group-based T designed to be more challenging for participants, but they are important for walking and can improve mobility -Dr Jennifer Brach, Study Investigator Consumer.HealthDay.com article Goal 2: Speed Uptake and Use of Information Uptake of Results from PCORI-Funded Studies in UpToDate® Recent results from a PCORI-funded study on self-monitoring of blood glucose (SMBG) have been taken up in UpToDate®, a point-of-care, evidence-based medical resource software used by more than 1.3 million clinicians in 187 countries, including nearly 90% of major academic medical centers in the United States1 • Topic page titled: Self-monitoring of blood glucose in management of adults with diabetes mellitus, updated Oct 31, 20172 o Young LA, et al Glucose Self-monitoring in Non Insulin-Treated Patients With Type Diabetes in Primary Care Settings: A Randomized Trial JAMA Internal June 2017 • PI: Katrina Donahue, MD, MPH, University of North Carolina at Chapel Hill At least CER results publications from PCORI-funded studies have now been taken up in UpToDate® 1UpToDate About Us UpToDate®, Inc 2017 https://www.uptodate.com/home/about-us Self-monitoring of blood glucose in management of adults with diabetes mellitus In: UpToDate®, Hirsch, IB (ed), UpToDate®, Waltham, MA, 2017 2McCulloch, DK Goal 3: Influencing Research Example: Establishment of Policies and Programs to Promote PCOR A PCORI-funded project (PI: Peter Kohler, MD, University of Arkansas for Medical Sciences) has inspired policy changes and capacity building efforts at the University of Arkansas for Medical Science (UAMS) Policy changes: • • Hiring policy: Redefining the classification and necessary qualifications for research coordinators, interpreters, and community health workers representing the communities of research focus IRB Dissemination policy on returning results to the community and study participants (implementation in progress) Capacity building: • • Implementation of a training on the responsible conduct of research for non-academic research partners Bolstered services offered through Community Engagement component of the UAMS Translational Research Institute to mentor ~25 UAMS researchers [Peter Kohler, MD & Pearl McElfish, Ph.D; July 2017] $1.95B Committed to Research through FY-2017 Cumulative Funds Committed to Research and Research Infrastructure 2500 $2.39B Budgeted End FY-18 2000 $ Millions $1.95B End FY-17 1500 $1.6B End FY-16 $1.2B End FY-15 1000 $683M 500 End FY-14 $333M End FY-14 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 2012 2013 2014 2015 2016 2017 2018 Cumulative Research & Research Infrastructure Funding Commitments by National Priority for Research as of FY-2017 Research and Research Infrastructure Commitments by National Priority as of 9/30/2017 Addressing Disparities, $235M, 12% Accelerating Patient-Centered Research and Methodological Research, $480M, 25% Subset: PCORnet Infrastructure and Workforce Training, $355M, 18% Communication and Dissemination Research, $109M, 6% Subset: Methods Research, $125M, 6% $1.948B Improving Healthcare Systems, $451M, 23% Assessment of Prevention, Diagnosis, and Treatment Options, $672M, 34% We are making progress on our Strategic Priority to “Increase the proportion of research funding going to focused and targeted topics” Cumulative Funds Committed to Research by Fiscal Year 2,000 Broad 60% Targeted Pragmatic 52% % of Funding to Focused/Targeted Research 1,500 $ Millions 46% $332 40% 1,250 50% 40% $258 1,000 $483 $179 30% $321 750 20% 500 250 17% $50 20% $186 % Focused / Targeted 1,750 $108 $440 $555 $669 $746 10% $244 0% Cumulative as of FY-2013 Cumulative as of FY-2014 Cumulative as of FY-2015 Cumulative as of FY-2016 Cumulative as of FY-2017 Status of PCORI-Funded Research Projects Status of PCORI-Funded Research Projects N=496, as of Q4-17 350 300 A refers to the PCORI contract period, which includes both the research period and PCORI Peer Review 311 250 200 150 123 100 50 36 Awarded; Contract Pending Active; Too early for quarterly project evaluation Active; Eligible for quarterly project evaluation Complete; Complete; Active; Active; Summaries Results posted DFRR due and In PCORI Peer to PCORI.org being Review not yet (during all of developed for submitted posting Q4) Terminated *Does not include Pilots, Infrastructure, or D&I awards *Does not include studies awarded in Q1-2018 *This slide includes a correction identified during the original presentation We are monitoring trends and shifts in project status Project Status by Color Zones Q3-15 to Q4-17 90 78 80 72 70 79 79 77 74 67 70 Percent of Projects (%) 73 78 Green Zone 60 Yellow Zone 50 Off Track (Orange/Red) 40 Award Terminated* 30 25 22 21 20 21 18 20 10 9 Q3-16 Q4-16 16 16 17 5 Q1-17 Q2-17 Q3-17 17 Q3-15 Q4-15 Q1-16 Q2-16 Q4-17 *Notice of Termination Issued, 90% Q2 Q3 Q4 % of Draft Final Research Reports On Time 33 200 300 $ Millions Public Reporting of Research Findings PCORI Peer Review Completed as of Q4: 12 Target > 90% N= 100 % of Projects On Track Draft Final Research Reports 50 50 Process 200 300 $ Millions Actual 70 Goal 1: Increasing Information A PCORI-funded study comparing two programs to prevent falls among older adults found that a groupbased standing-exercise program called On The Move is more effective than commonly used seated exercises Target 100 % Uptake 100 80 Percent Total FY-17 $379M $423M for FY-2017 Outputs Actual Percent 90 Budgeted Projects Budgeted Operating Budget and Research Awards Target > 90% 100 Use Includes funds committed to PCORnet Q4 2017 Narrative Examples Budget Inputs Project Performance Funds Committed to Research Q1 2017 Q2 2017 Q3 2017 14