MEDICAL INFORMATICS Edited by Shaul Mordechai and Ranjit Sahu Medical Informatics Edited by Shaul Mordechai and Ranjit Sahu Published by InTech Janeza Trdine 9, 51000 Rijeka, Croatia Copyright © 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license, which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials, instructions, methods or ideas contained in the book. Publishing Process Manager Oliver Kurelic Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published March, 2012 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechweb.org Medical Informatics, Edited by Shaul Mordechai and Ranjit Sahu p. cm. ISBN 978-953-51-0259-5 Contents Preface IX Part 1 Information Technology 1 Chapter 1 Innovative Integration of Information Systems for Managing a National Access to Surgery 3 Luís Velez Lapão Chapter 2 Anonymization Approach for Protect Privacy of Medical Data and Knowledge Management 25 Asmaa Hatem Rashid and Norizan Binti Mohd Yasin Part 2 Bioinformatics Methods 39 Chapter 3 Aligning Biomedical Terminologies in French: Towards Semantic Interoperability in Medical Applications 41 Tayeb Merabti, Lina F. Soualmia, Julien Grosjean, Michel Joubert and Stefan J. Darmoni Chapter 4 A Comprehensive Analysis of MALDI-TOF Spectrometry Data 69 Malgorzata Plechawska-Wojcik Part 3 Clinical Applications 91 Chapter 5 Using Brazilian Digital TV to Integrate Health Care Services Embedded in Medical Commercial Devices 93 Vandermi Silva, Ricardo Erikson Veras De Sena Rosa and Vicente Ferreira De Lucena Jr. Chapter 6 Real Time Clinical Decision Support System 111 Hsueh-Chun Lin VI Contents Chapter 7 Wireless Monitoring of Patient’s Vital Signs 137 Anna G. C. D. Ribeiro, André L. Maitelli, Ricardo A. M. Valentim, Cicília Raquel Maia Leite and Ana M. G. Guerreiro Preface The advent of newer technologies along with the developments in the field of computer software and information technologies has been revolutionizing everyday life. It has also impacted the field of biomedicine and health care, bringing into its ambit additional dimensions of database creation for analysis of patient samples, in retrospect or in real time, making impressive changes to the way health care and patient information is recorded, processed, interpreted and utilized for improving the quality of life. The book consists of seven chapters, dealing with three major issues of medical information gathering from patient's and health care professional’s perspective, translational approaches from a researcher point of view, and finally the application potential as required by the clinicians. The first section of the book consists of two chapters that detail the basic process of acquisition of information in a health system, and how the barriers of language can play a role in creating a noise in transmission of information through a medical system. These chapters emphasize the ways to make the system comprehensible to both the clinician/physician as well as to the patient, the source and the recipient. A chapter by Msc. Rashid is also included in this section, wherein the issue dealt with is the protection of the individuals' identities while disseminating required information to the designated personnel. This section intends to especially educate the people with expertise in information technology who are involved in medical fields, thereby aiding in their discretion of data collection, evaluation, storage and supply in clinical set ups. The chapters also describe the design and first results of using an information system to improve the access to surgery by re-defining key processes and workflows. The use of the proposed systems has the potential to improve health care quality and prevent medical errors, as well as increasing the efficiency of the care provided and reducing unnecessary health care costs. Section II deals with technological developments that have been invading the health system, with the example of MALDI-TOF and its application in prostate cancer diagnosis and monitoring. It demonstrates the requirement of translating scientific concepts and jargons to the common men in lay terms, through the use of information systems. The section also includes a chapter about the integration of technological X Preface breakthroughs, patients, physicians and the information system, and principles laid out in the studies help to demonstrate the increased effectiveness of communication between the source and the recipient. There is currently extensive literature on mass spectra analysis problems. In the chapter "A comprehensive analysis of MALDI-TOF spectrometry data" the successful preprocessing as a condition of reliable mass spectrometry data analysis is emphasized. All elements of mass spectra analysis are closely related. Any performed operation has an influence on the further quality of the results. Not only are the set of methods and parameters important, but the proper order of methods is also important. Another important issue in mass spectrometry data analysis is the supporting of biological interpretation. Biological interpretation tries to determine peptides and proteins on the basis of the m/z values list. The ability to check the details of those components is of great importance to biologists. The final section encompasses chapters that deal with realistic evaluation of the principles of medical informatics in terms of relevance to the patients. The practical utility of any break through in science requires an evaluation under everyday conditions. Since medical informatics is a growing and upcoming field, it is routinely subjected to scrutiny for its relevance. The chapters in section III are thus examples of how the medical informatics system is likely to integrate into the lives of both patients and the medical professionals. The chapter "WIRELESS MONITORING OF PATIENT’S VITAL SIGNS", proposes a wireless monitoring of patient’s vital signs, presenting a new telemedicine software using GPRS (General Packet Radio Service) and Bluetooth technologies that add the idea of ubiquity to the medical area, innovating the relation between doctors and patients through wireless communication and bringing security and confidence to a patient being monitored in home care. Lastly, the chapter "Using Brazilian Digital TV to Integrate Health Care Services Embedded in Medical Commercial Devices" shows how to construct highly integrated systems for measuring and collecting patients’ data, aimed at assisting in diagnoses, prevention of diseases and patient care under real world situations, using the information highways of the virtual world. Ranjit Sahu Center for Autoimmune and Musculoskeletal Diseases Feinstein Institute for Medical Research Manhasset NY USA Shaul Mordechai Head, Biomedical Spectroscopy Department of Physics, Ben Gurion University Beer-Sheva Israel . MEDICAL INFORMATICS Edited by Shaul Mordechai and Ranjit Sahu Medical Informatics Edited by Shaul Mordechai and Ranjit Sahu. can be obtained from orders@intechweb.org Medical Informatics, Edited by Shaul Mordechai and Ranjit Sahu p. cm. ISBN 978-953-51-0259-5