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BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance placed on this supplemental material which has been supplied by the author(s) Supplemental material Tob Control Supplementary Information for JUUL ‘NEW TECHNOLOGY’ PODS EXHIBIT GREATER ELECTRICAL POWER AND NICOTINE OUTPUT THAN PREVIOUS DEVICES Ebrahim Karam1,3, BE; Soha Talih1,3, PhD; Rola Salman1,3, BS; Rachel El-Hage1,2, MS; Nareg Karaoghlanian1,3, BE; Ahmad El-Hellani1,2, PhD; Najat Saliba1,2, PhD; Alan Shihadeh1,3, ScD* Mechanical Engineering Department, Maroun Semaan Faculty of Engineering and Architecture, American University of Beirut, Bliss Street, PO Box 11-0236, Beirut, Lebanon Chemistry Department, Faculty of Arts and Sciences, American University of Beirut, Bliss Street, PO Box 11-0236, Beirut, Lebanon Center for the Study of Tobacco Products, Virginia Commonwealth University, 821 West Franklin Street, Richmond, Virginia 23284, United States * Corresponding Author: Alan Shihadeh Tel: + 961 344444 Email address: as20@aub.edu.lb Address: American University of Beirut PO Box 11-0236 Beirut, Lebanon Karam E, et al Tob Control 2021;0:1–5 doi: 10.1136/tobaccocontrol-2020-056427 Supplemental material BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance placed on this supplemental material which has been supplied by the author(s) Tob Control The thermogravimetric analysis spectrum obtained for the new technology JUUL wick showed a decay in % mass between 300 and 400oC (Figure S1), which matches the degradation profile of cotton reported in the literature.1 Figure S1 TGA spectrum of the degradation of JUUL new technology wick The FTIR spectra of the degradation products in the mass decay region between 300 and 450oC showed the generation of typical cotton pyrolytic degradation products including molecules with free OH (glucose) and C=O bands (carbonyl compounds), in addition to small gases (CO and CO2) (Figure S2).2,3 Karam E, et al Tob Control 2021;0:1–5 doi: 10.1136/tobaccocontrol-2020-056427 BMJ Publishing Group Limited (BMJ) disclaims all liability and responsibility arising from any reliance placed on this supplemental material which has been supplied by the author(s) Supplemental material 300 C 350 C Tob Control 430 C 0.09 CO2 0.08 0.07 C=O stretches (carbonyls) 0.06 0.05 0.04 0.03 C-O stretches 0.02 C-H stretches 0.01 OH stretches CO 650 1150 1650 2150 2650 Wavenumbers 3150 3650 4150 (cm-1) Figure S2 FTIR spectra of the degradation of the new technology JUUL wick between 300 and 450 oC Noureddine Abidi, Eric Hequet, Dean Ethridge Thermogravimetric Analysis of Cotton Fibers: Relationships with Maturity and Fineness Journal of Applied Polymer Science, 2007, 103(6):3476-3482 D.K Shen, S Gu The mechanism for thermal decomposition of cellulose and its main products Bioresource Technology, 2009,100:6496–6504 Robert f schwenker, jr., Eugene pacsu Pyrolytic Degradation Products of Cellulose CHEMICAL AND ENGINEERING DATA SERIES, 1957, 2, 83-88 Karam E, et al Tob Control 2021;0:1–5 doi: 10.1136/tobaccocontrol-2020-056427

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