Site Lesion Cause Cornea Scar Ulcer Lens Cataracts Metabolic: galactosemia, galactokinase deficiency Viral: Rubella, CMV Traumatic: nonaccidental trauma, birth injury, blunt trauma, perforation of globe Chromosomal: trisomies, Turner syndrome Genetic: aniridia, Treacher Collins, Pierre Robin, Rubinstein–Taybi, Hallermann–Streiff Endocrine: congenital hypoparathyroidism, Albright hereditary osteodystrophy Neurologic: Sjögren syndrome, Smith–Lemli– Opitz Lens Subluxation Fundus Coloboma of fundus Retinoblastoma Persistent hyperplastic primary vitreous Norrie disease Incontinenta pigmenti Retinal dysplasia Marfan syndrome, homocysteinuria, sulfite oxidase deficiency, hyperlysinemia, Ehlers– Danlos, Weill–Marchesani syndrome, trauma Norrie disease-X-linked recessive