Site Species Katayama fever All Symptoms Diagnosis Fever, malaise, cough, Serology; can help rash, abdominal pain, with speciation, nausea, diarrhea, but cannot tender differentiate hepatosplenomegaly, ongoing infection, lymphadenopathy, and recent infection, or eosinophilia past infection Intestinal S mansoni, S Low worm burden: may Identification of eggs japonicum, be asymptomatic or in the stool S mekongi, have mild symptoms (several specimens S may be necessary) Moderate–severe worm intercalatum burden: mucoid bloody diarrhea, tender hepatomegaly Late findings: portal hypertension, ascites, esophageal varices, and hematemesis Urinary S hematobium Dysuria, urgency, Microscopic frequency; examination of microscopic or gross urine (egg hematuria Late excretion in urine findings: bladder typically peaks fibrosis and bladder between noon and cancer pm); bladder biopsy may be necessary Genital tract S hematobium Males: obstructive Microscopic uropathy, rare examination of involvement of urine (egg prostate, testes, excretion in urine epididymis, and penis typically peaks between noon and Females: ulcerating pm) polypoid or nodular lesions of the vulva,