allo-responses via the TH2 pathway: relevance to tissue engineering human heart valves Tissue Eng 2006;12(8):2263–2273 83 El-Hamamsy I, et al Long-term outcomes after autograft versus homograft aortic root replacement in adults with aortic valve disease: a randomised controlled trial Lancet 2010;376(9740):524–531 84 Godown J, et al Handheld echocardiography versus auscultation for detection of rheumatic heart disease Pediatrics 2015;135(4):e939– e944 85 Roberts K, et al Echocardiographic screening for rheumatic heart disease in high and low risk Australian children Circulation 2014;129(19):1953–1961 86 Webb RH, et al Valvular regurgitation using portable echocardiography in a healthy student population: implications for rheumatic heart disease screening J Am Soc Echocardiogr 2015;28(8):981–988 87 Engelman D, et al Screening-detected rheumatic heart disease can progress to severe disease Heart Asia 2016;8(2):67–73 88 Engelman D, et al Clinical outcomes for young people with screening-detected and clinicallydiagnosed rheumatic heart disease in Fiji Int J Cardiol 2017;240:422–427 89 Remond M, et al Are minor echocardiographic changes associated with an increased risk of acute rheumatic fever or progression to rheumatic heart disease? Int J Cardiol 2015;198:117–122 90 Engelman D, et al Focused cardiac ultrasound screening for rheumatic heart disease by briefly trained health workers: a study of diagnostic accuracy Lancet Glob Health 2016;4(6):e386– e394 91 Ploutz M, et al Handheld echocardiographic screening for rheumatic heart disease by nonexperts Heart 2016;102(1):35–39 92 Yacoub M, et al Taking cardiac surgery to the people J Cardiovasc Transl Res 2014;7(9):797– 802 93 Yacoub MH Establishing pediatric cardiovascular services in the developing world: a wake-up call Circulation 2007;116(17):1876– 1878 94 Yacoub M, et al Eliminating acute rheumatic fever and rheumatic heart disease Lancet 2017;390(10091):212–213 95 Watkins D, et al Seven key actions to eradicate rheumatic heart disease in Africa: the addis ababa communique Cardiovasc J Afr 2016;27(3):184–187 96 Yacoub M, Hosny H, Afifi A Improving postoperative outcome of congenital heart surgery in low/middle-income countries: climbing mount excellence Heart 2017 ... Taking cardiac surgery to the people J Cardiovasc Transl Res 2014;7(9):797– 802 93 Yacoub MH Establishing pediatric cardiovascular services in the developing world: a wake-up call Circulation 2007;116(17):1876–