levels higher than 90 to 100 mg/dL after acute ingestion or 60 mg/dL or higher after chronic salicylism Specific indications for hemodialysis include (i) severe acidosis or other electrolyte disturbance, (ii) renal failure, (iii) persistent neurologic dysfunction, (iv) pulmonary edema, and/or (v) progressive clinical deterioration despite standard treatment Criteria for Admission or Discharge: Patients who are clinically asymptomatic with either undetectable or downtrending serial salicylate levels