MAVRIC a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage Original Research ajog org OBSTETRICS MAVRIC a multicenter randomized controlled trial of transabdo.
Original Research ajog.org OBSTETRICS MAVRIC: a multicenter randomized controlled trial of transabdominal vs transvaginal cervical cerclage Andrew Shennan, MD; Manju Chandiramani, PhD; Phillip Bennett, PhD; Anna L David, PhD; Joanna Girling, MA; Alexandra Ridout, MBBS; Paul T Seed, PhD; Nigel Simpson, MBBS; Steven Thornton, PhD; Graham Tydeman, FRCOG; Siobhan Quenby, PhD; Jenny Carter, PhD BACKGROUND: Vaginal cerclage (a suture around the cervix) commonly is placed in women with recurrent pregnancy loss These women may experience late miscarriage or extreme preterm delivery, despite being treated with cerclage Transabdominal cerclage has been advocated after failed cerclage, although its efficacy is unproved by randomized controlled trial OBJECTIVE: The objective of this study was to compare transabdominal cerclage or high vaginal cerclage with low vaginal cerclage in women with a history of failed cerclage Our primary outcome was delivery at