MAVRIC A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage Journal Pre proof MAVRIC A Multicentre Randomised Controlled Trial of Transabdominal Versus Tra.
Journal Pre-proof MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage Andrew Shennan, Manju Chandiramani, Phillip Bennett, Anna L David, Joanna Girling, Alexandra Ridout, Mr Paul T Seed, Nigel Simpson, Steven Thornton, Graham Tydeman, Siobhan Quenby, Jenny Carter PII: S0002-9378(19)31206-2 DOI: https://doi.org/10.1016/j.ajog.2019.09.040 Reference: YMOB 12906 To appear in: American Journal of Obstetrics and Gynecology Received Date: July 2019 Revised Date: 30 August 2019 Accepted Date: 16 September 2019 Please cite this article as: Shennan A, Chandiramani M, Bennett P, David AL, Girling J, Ridout A, Seed PT, Simpson N, Thornton S, Tydeman G, Quenby S, Carter J, MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage, American Journal of Obstetrics and Gynecology (2019), doi: https://doi.org/10.1016/j.ajog.2019.09.040 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain © 2019 Published by Elsevier Inc MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage Andrew SHENNANa, Manju CHANDIRAMANIa, Phillip BENNETTb, Anna L DAVIDc Joanna GIRLINGd, Alexandra RIDOUTa, Mr Paul T SEEDa, Nigel SIMPSONe, Steven THORNTONf, Graham TYDEMANg, Siobhan QUENBYh, Jenny CARTERa a School of Life Course Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, SE1 7EH, UK Department of Women and Children’s Health 10 11 b 12 Institute of Reproductive and Development Biology, 13 14 15 16 Imperial College London, Du Cane Road, London W12 0NN, UK 17 University College London, 18 Medical School Building, 19 74 Huntley Street, London WC1E 6AU c Parturition Research Group UCL EGA Institute for Women’s Health 20 21 d 22 West Middlesex University Hospital, 23 Chelsea and Westminster Hospital NHS Foundation Trust 24 Twickenham Road, Middlesex TW7 6AF Department of Obstetrics and Gynaecology 25 26 e 27 University of Leeds 28 Worsley Building, Clarendon Way, Leeds LS2 9NL Department of Women’s and Children’s Health 29 30 f 31 Queen Mary University of London Charterhouse Square, 32 London EC1M 6BQ Barts and the London School of Medicine and Dentistry, 33 34 g 35 Hayfield House, Hayfield Road, Kirkcaldy, KY2 5AH Forth Park Hospital, Fife 36 37 h 38 University of Warwick, Coventry, UK Division of Biomedical Sciences, Warwick Medical School 39 Corresponding Author: 40 Andrew Shennan 41 a 42 School of Life Course Sciences, Faculty of Life Sciences and Medicine, 43 King’s College London, London, SE1 7EH, UK 44 Andrew.shennan@kcl.ac.uk 45 46 +447976822634 Department of Women and Children’s Health, 47 48 “Declaration of interests” (all authors) 49 None to declare 50 Funding: The trial was registered with the WHO International Clinical Trials Registry Platform 51 (ISRCTN33404560) and funded by J P Moulton Charitable Foundation (Registered Charity No 1109891) PTS 52 is partly funded by Tommy’s (Registered charity no 1060508) and by CLAHRC South London (NIHR) 53 Condensation: Abdominal cerclage was demonstrated to be superior to low vaginal cerclage in women with 54 prior failed cerclage in preventing early preterm birth (