[...]... Neuroscience, Molecular Medicine Section, University of Siena, Siena, Italy Francesca Sozio, MS Department of Neuroscience, Molecular Medicine Section, University of Siena, Siena, Italy Matt Thompson, MD, FRCS Vascular Surgery, St George’s Vascular Institute, St George’s Hospital, London, UK Andrew Tinker, Department of Medicine, University College London, London, UK Janice Tsui, MD, FRCS Royal Free Vascular Unit,... endothelial growth factor Vascular endothelial growth factor receptor Vascular endothelial growth factor receptor 2 von Hippel–Lindau tumor suppressor Vasoactive intestinal peptide Vascular smooth muscle cells von Willebrand factor Section I Hot Topics in Vascular Biology 1 Pericytes: Adaptable Vascular Progenitors Gareth D Hyde and Ann E Canfield 1.1 General Introduction The existence of perivascular cells associated... A.E Canfield (*) Wellcome Trust Centre for Cell-Matrix Research & Cardiovascular Research Group, The Michael Smith Building, School of Biomedicine, Faculty of Medical & Human Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK e-mail: ann.canfield@manchester.ac.uk D Abraham et al (eds.), Translational Vascular Medicine, DOI 10.1007/978-0-85729-920-8_1, © Springer-Verlag London Limited... Neuroscience, Molecular Medicine Section, University of Siena, Siena, Italy George Hamilton, MD, FRCS Royal Free Vascular Unit, Royal Free Hampstead NHS Trust, London, UK Stephen C Harmer, Department of Medicine, University College London, London, UK Kristin B Highland, MD, MSCR Pulmonary Hypertension Program, Medical University of South Carolina, Charleston, SC, USA Rob Hinchliffe, MD, FRCS Vascular Surgery,... expressed on the cell surface of microvascular pericytes J Exp Med 1988;167:1003–15 10 DeNofrio D, Hoock TC, Herman IM Functional sorting of actin isoforms in microvascular pericytes J Cell Biol 1989;109:191–202 11 Herman IM, D’Amore PA Microvascular pericytes contain muscle and nonmuscle actins J Cell Biol 1985;101:43–52 12 Nehls V, Drenckhahn D Heterogeneity of microvascular pericytes for smooth muscle... subunit is regulated through posttranslational modification by HIF prolyl hydroxylases (PHDs, prolyl hydroxylase domain): PHD1, 2 and 3 (reviewed in Kaelin and Ratcliffe [1]) T Bishop (*) • P.J Ratcliffe Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK e-mail: tammie@well.ox.ac.uk; pjr@well.ox.ac.uk D Abraham et al (eds.), Translational Vascular Medicine, DOI 10.1007/978-0-85729-920-8_2,... Cardiovascular Research Group, The Michael Smith Building, School of Biomedicine, Faculty of Medical & Human Sciences, University of Manchester, Manchester, UK Shalini Jadeja, Medical and Developmental Genetics, MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK James Leiper, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, UK Ian Loftus, MD, FRCS Vascular. .. differentiation of vascular pericytes: implications for vascular calcification Circ Res 2006;98:1264–72 64 Bianco P, Riminucci M, Gronthos S, Robey PG Bone marrow stromal stem cells: nature, biology, and potential applications Stem Cells 2001;19:180–92 65 Short B, Brouard N, Occhiodoro-Scott T, Ramakrishnan A, Simmons PJ Mesenchymal stem cells Arch Med Res 2003;34:565–71 1 Pericytes: Adaptable Vascular Progenitors... Davies JE Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors Stem Cells 2005;23:220–9 70 Zannettino AC, Paton S, Arthur A, et al Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo J Cell Physiol 2008;214:413–21 71 Tavazoie M, Van der Veken L, Silva-Vargas V, et al A specialized vascular niche for adult neural... MSCR Pulmonary Hypertension Program, Medical University of South Carolina, Charleston, SC, USA Rob Hinchliffe, MD, FRCS Vascular Surgery, St George’s Vascular Institute, St George’s Hospital, London, UK Peter Holt, PhD, FRCS Vascular Surgery, St George’s Vascular Institute, St George’s Hospital, London, UK Alice Huertas, Faculté de médecine, Univ Paris-Sud, Kremlin-Bicêtre, France Service de Pneumologie . h0" alt="" Translational Vascular Medicine David Abraham • Clive Handler Michael Dashwood • Gerry Coghlan Editors Translational Vascular Medicine Pathogenesis,. in cardiovascular medicine. As before, we have tried to explore the bi-directional and integrated approaches of translational cardiovascular medicine,