... differentiation of themesenchymal cells to chondrocytes causes a change inECM composition. Chondrocytes express cartilage-speci c type II, type IX and type XI collagen,proteoglycans, aggrecan, and ... bone.Sox9 represents an essential transcription factor ofthe chondrogenic lineage, and regulates the expressionof chondrocyte-speci c genes such as those encodingtype II collagen and CD-RAP [22,23]. ... Martinsried, GermanyThe family of activating enhancer-binding protein(AP)-2 transcription factors regulate their target genesthrough binding to the palindromic recognitionsequence 5¢-GCCN3GGC-3¢ or...