Drugs and Poisons in Humans - A Handbook of Practical Analysis (Part 24)

... rapid and distinct visual hallucination takes place 45 min–1 h a er oral intake of about 20 µg of LSD [1].  e hallucination becomes most marked 2–3 h a er the intake and lasts for 8–12 h. In ... LSD is rapidly metabolized in human bodies. As metabolites of LSD, 2-oxo-LSD, 3-, 1 3- and 14-hydroxy-LSDs and an N-de-ethyl-LSD are known [3]. A er oral ingestion of 160...

Ngày tải lên: 08/11/2013, 01:15

... are also used as aromatics. Because of their pharmacological e ect, alkyl nitrites are being abused as uncontrolled inhalant drugs and causing a social problem [4]. Although there are many reports ... headspace (HS)-gas chromatography (GC) and liquid-liquid extraction-GC are presented. Determination of isobutyl nitrite in aqueous solution by headspace-GC Reagents and their pr...

Ngày tải lên: 18/10/2013, 00:15

... concentrations of DAEMS are spiked into blank serum specimens containing a  xed amount of DAEMO (IS) each and extracted as described before. Since the base peaks of DAEMS and DAEMO (IS) equally appear ... biofluids by gas chromatography-mass spectrometry and liquid- liquid-solid phase-transfer-catalyzed pentafluorobenzylation. J Anal Toxicol 23:86–93 11) Black RM, Read RW (1998...

Ngày tải lên: 18/10/2013, 00:15

... EI mass spectra of ∆ 9 -THC, CBD, CBN and 5α-cholestane. GC analysis of cannabinoids in plant specimens 190 Cannabinoids and their metabolites GC/MS analysis of ∆ 9 -THC-11-oic acid in urine ... resin of the cannabis plant. Since the main component of cannabis, ∆ 9 -tetrahydrocannabi- nol ( ∆ 9 -THC), has various psychopharmacological e ects including hallucination, the...

Ngày tải lên: 24/10/2013, 19:15

... 8) Matsubara K, Fukushima S, Akane A et al. (1992) Increased urinary morphine, codeine and tetrahydropapavero- line in Parkinsonian patient undergoing L-3,4-dihydroxyphenylalanine therapy: a possible ... patient, several grams of an opiate do occasionally not cause death. Toxic and fatal concentrations 204 Morphine and its analogues As a result of analysis of 203 fatal c...

Ngày tải lên: 24/10/2013, 19:15

... methemoglobinemia be- comes severe, it causes cyanosis, headache, easy fatigability, respiratory and conciousness dis- turbances and  nally death.  e fatal methemoglobinemia is rare, but fatal ones a ... Various known amounts of nitrate and a  xed amount of IS are added to blank specimens and processed in the same way to construct a calibration curve.  e peak area ratio...

Ngày tải lên: 24/10/2013, 19:15

... pantherina 469 Amanita phalloides 469 Amanita verna 469, 474 Amanita virosa 469, 473 amanitin 473, 477, 479 amido-type local anesthetic 385 1-amino- 4- phenylbutane 173 2-amino-6-hydroxymethyl- 8-hydroxyquinazoline ... 165 N-methyl- 1-( 3,4-methylene- dioxyphenyl )-2 -butan- amine 229 N-methyl- 1-( 3,4-methylene- dioxyphenyl )-3 -butan- amine 233 N-methyl-bis(tri uoro- acetamide)...

Ngày tải lên: 24/10/2013, 19:15

... e author et al. experienced a fatal cocaine poisoning case and measured concentrations of cocaine and its metabolites in body  uids and various organs. A 41-year-old male was found dead in a ... suggesting a relatively short period between the times of his ingestion and death. In addi- tion, the ratios of cocaine to BE in blood and in the brain, and the br...

Ngày tải lên: 29/10/2013, 01:15

... composed of pen- 221 tazocine concentration in the horizontal axis and peak area ratio of pentazocine to IS in the vertical axis.  e peak area ratio of a test specimen is applied to the calibration ... commercially avail- able. ii. Preparation • Pentazocine and dextromethorphan solutions: the drugs are separately dissolved in appro- priate amount of methanol; a 10–20...

Ngày tải lên: 29/10/2013, 02:15

... LC/MS analyses of MDAs in the forms of tablets and those for GC/MS analysis of MDAs and their main metabolites 4-hydroxy-3-me- thoxymethamphetamine ( HMMA) and 4-hydroxy-3-methoxyamphetamine ( HMA) ... simultaneou determination of amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, and 3,4-methylenedioxyethyl- amphe tamine in u...

Ngày tải lên: 08/11/2013, 01:15