... associated with accidents in the sewer and mining industry The gas is not only soluble in water, but also in petroleum H2S inhibits enzymes in mitochondria by binding with Fe3+ of cytochrome oxidase ... を中心に】神経中毒 硫化水素中毒 Clinical Neuroscience 2009, 27(8):894-896 doi:10.1186/1745-6673-5-28 Cite this article as: Morii et al.: Japanese experience of hydrogen...
Ngày tải lên: 20/06/2014, 00:20
... models of inflammation In those models of inflammation plasma H2S level, tissue H2S synthesizing enzyme activity and CSE expression were increased and inhibition of H2S synthesis by DL-propargylglycine ... http://www.journal -inflammation. com/content/6/1/35 Abbreviations H2S: Hydrogen sulfide; NaHS: Sodium hydrosulfide; MPO: Myeloperoxidase; CBS: Cystathionine β-synthetase; CS...
Ngày tải lên: 11/08/2014, 08:22
Báo cáo y học: " Bench-to-bedside review: Hydrogen sulfide – the third gaseous transmitter: applications for critical care" pptx
... Bhatia M: Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human κ monocyte cell line U937 via the ERK–NF-κB pathway J Leukoc Biol 2007, 81:1322-1332 Ubuka T: Assay methods ... ES, Taylor EA, Moore PK: Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery J Pharmacol Exp Ther 2008, 324:876882 Bhat...
Ngày tải lên: 13/08/2014, 11:23
Báo cáo y học: "Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in rats" potx
... effects of the hydrogen sulfide donor Moreover, we did not assess the effects of NaHS on inflammation and oxidative stress in non hemorrhagic rats since the injection of a single dose of 0.2 mg/kg of ... et al.: Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in...
Ngày tải lên: 13/08/2014, 21:21
Báo cáo y học: " Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic and vasomotor effects" ppt
... article as: Derwall et al.: Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic ... [31] Inhibitory effects of H2S in the presence of increased metabolism in larger mammals warrants further study Page of 10 Our resu...
Ngày tải lên: 14/08/2014, 07:21
A novel and cost effective hydrogen sulfide removal technology us
... However, using low H2S concentrations and given sufficient time, removal capacities of impregnated and unimpreganted activated appear to be comparable in laboratory tests Removal capacities may vary ... caustics are used, the activated carbon acts more as a passive support for the caustics rather than actively participating in the H2S removal because of its low catalytic ability T...
Ngày tải lên: 27/02/2015, 09:19
The role of hydrogen sulfide in the central nervous system implications in the treatment of alzheimers disease
... THE ROLE OF HYDROGEN SULFIDE IN THE CENTRAL NERVOUS SYSTEM: IMPLICATIONS IN TREATMENT OF ALZHEIMER’S DISEASE BHUSHAN VIJAY NAGPURE (M.B.B.S., Maharashtra University of Health Sciences, India) ... lot of efforts have been put into the development of disease- modifying drug therapy Amyloidogenesis is one of the main culprits of AD pathology The effe...
Ngày tải lên: 09/09/2015, 08:17
Hydrogen sulfide and neurogenic inflammation in a murine model of polymicrobial sepsis
... established as a novel mediator of inflammation It has been demonstrated to play a pro-inflammatory role in animal models of local and systemic inflammation, including carrageenan-induced hindpaw ... 3-mercaptopyruvate sulfurtransferase AC adenylyl cyclase AECOPD Acute exarcebation of chronic obsructive pulmonary disease ALI Acute lung injury ALT Alanine aminotransferase ANOV...
Ngày tải lên: 10/09/2015, 08:32
The role of hydrogen sulfide in normal and ischemic heart
... Summary Ischemic heart disease is the leading cause of death in the western society and a major health problem in developing countries In the current study, the role of hydrogen sulfide (H2S) in the ... blood flow into and out of the heart A region of the heart called the sinoatrial (SA) node is capable of producing and discharging an acti...
Ngày tải lên: 11/09/2015, 09:57
Role of hydrogen sulfide in the pathogenesis of parkinsons disease
... contains the N-terminal heme-binding domain, the catalytic domain, and the C-terminal regulatory domain Two other gaseous transmitters, CO and NO, can bind to the heme-binding domain and result in ... be elevated in the SN from parkinsonian brains (138) In support of these findings, epidemiological studies reveal a role of neuroinflammation in the progression of PD...
Ngày tải lên: 11/09/2015, 10:18
Roles and relationship of gasotransmitters hydrogen sulfide nitric oxide in myocardial infarction
... accounting for 20% of all deaths in 2007 (Ministry of Health, 2009) INTRODUCTION 1.2 MYOCARDIAL INFARCTION (MI) 1.2.1 Pathophysiology and Management of Myocardial Infarction Myocardial infarction, ... common platform using both donors and inhibitors of H2 S and NO in in vivo MI mode ls NaHS and molsidomine attenuated infarct enlargement and improved survival w...
Ngày tải lên: 14/09/2015, 08:45
Hydrogen sulfide, a cardioprotective agent in ischemic heart
... the accumulation of metabolites and inorganic phosphate With a substantial decline in ATP, the Na+, K+-ATPase is inhibited, resulting in a further decline of K+ and an increase in Na+ Intracellular ... stress, and cell adherence They function in a three-tier module comprising of a MAPK kinase kinase, a MAPK kinase and a MAPK The mammalian MAPK can be subdivided into five f...
Ngày tải lên: 14/09/2015, 14:05
A novel role of hydrogen sulfide in wound healing and a new approach to wound dressing in rat model
... inflammation and wound recovery after PAG administration (3) Compare the H2S releasing profiles and outcomes of S-diclofenac administration and PAG incorporated hydrogel dressing on wound healing ... microplate reader (Tecan Systems Inc.) All standards and samples were assayed in duplicate The H2S concentration of each sample was calculated according to a standard cu...
Ngày tải lên: 26/09/2015, 09:39
Role of hydrogen sulfide in the cardiovascular system implications for treatment of cardiovascular diseases
... alkaline conditions and in the presence of DTT, a strong reducing agent 64 Therefore, the physiologic relevance of 3- MST as a source of H2S formation in brain remains to be elucidated in the ... Renin is the rate-limiting enzyme involved in renin-angiotensin system Renin elevation occurs during pathological states of renal ischemia (renin in systematic circulation...
Ngày tải lên: 01/10/2015, 17:27
Hydrogen sulfide produces cardioprotective effects against ischemia reperfusion injury via regulation of intracelluar PH
... value in the group of myocytes subjected to ischemia/ reperfusion injury 30 3.2 NaHS induced cardioprotection via regulation of intracellular pH 3.2.1 Effect of NaHS on pHi in the rat ventricular ... the cell viability of cardiac myocytes subjected to ischemia (30 min) /reperfusion (10 min) C, group data show the protective effects of NaHS against the cardiac my...
Ngày tải lên: 02/10/2015, 17:13