Design of controlled release drug delivery systems (mcgraw hill chemical engineering) xiaolin

... tolerance of a variety of manufacturing methods Polymeric drug delivery systems under wide investigations are classified according to the mechanism controlling the release of the drug Some of the basic ... give benefits to drug companies by creating new forms of established drugs and offering improved versions of drugs It has been shown that companies developing new dru...

Ngày tải lên: 13/09/2015, 19:46

... of drug- polymer melt This thesis presents a step-by-step approach in the analysis of the use of foams for controlled release of Paclitaxel as implants within the brain for the post- surgical treatment ... developing controlled releases implants in the form of discs for Paclitaxel to be surgically inserted to remove remaining tumor cells aft...

Ngày tải lên: 05/10/2015, 21:33

... Chemical Aspects of Drug Delivery Systems Chemical Aspects of Drug Delivery Systems Edited by D R Karsa Akcros Chemicals UK Ltd., Manchester R A Stephenson Chemical Consultant ... solubility and stability Chemical Aspects of Drug Delivery Systems Table Routes of administration and general classification of drug delivery systems ROUTES OF ADMIN...

Ngày tải lên: 28/03/2014, 10:20

... On the completion of this course, the student should be able to have a deep understanding of the chemical aspects of drug delivery systems that have recently attracted attention from the chemistry ... Society of Chemistry, American Chemical Society, Wiley InterScience journals… CONTENTS Generalities of drug delivery Liposomes as drug delivery systems Polym...

Ngày tải lên: 18/04/2014, 15:37

... thinking Because of the synthesis impairment, acetylcholine is decreased in the neurons in the Alzheimer disease brain, leading to the incapability of learning, memory, and thinking Providing ... there are great possibilities for them to be used in the construction of drug delivery systems in not too long a time The functionalization of CNTs used in the...

Ngày tải lên: 20/06/2014, 22:20

... DESIGN AND FABRICATION OF MICRONEEDLES FOR DRUG DELIVERY JI JING ( B.Eng.,M.Eng., NWPU, CHINA) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF MECHANICAL ... Many of fabricated microneedles are designed for transdermal therapies to deliver drugs such as insulin and heparin On the other hand, microneedles can also be used for local d...

Ngày tải lên: 14/09/2015, 11:17

... for Drug Delivery Systems Drug delivery systems modify the kinetics or the location of the escape of the drug from the medicine Tables 15.1 and 15.2 provide generic reasons for using drug delivery ... numerous types of protein drug [21–23] 15.6 Examples of Biodegradable Polymer Drug Delivery Systems Under Development 15.6.1 Polyketals Polyketal-based drug delivery...

Ngày tải lên: 25/10/2013, 08:20

... the widespread application of nanodelivery systems in medicine Design of nanotechnology – based drug delivery Systems Nanoparticles can be used in targeted drug delivery at the site of disease ... the uptake of poorly soluble drugs [8,9], the targeting of drugs to a specific site, and drug bioavailability A schematic comparison of untargeted and targeted drug delivery systems is...

Ngày tải lên: 20/06/2014, 00:20

... concentration on the surface of the film and finally ks is the desorption rate constant Substituting known values and by fitting the experimental data with the mathematical model of Eq 1, the h value ... bulk, C10 is the concentration inside the gel, S and V1 are, respectively, the surface and the volume of film, V2 is the volume of the bulk, h is the mas...

Ngày tải lên: 22/06/2014, 00:20

... York, NY 10 016 tel: 21 2-6 9 6-9 000; fax: 21 2-6 8 5-4 540 Eastern Hemisphere Distribution Marcel Dekker AG Hutgasse 4, Postfach 812 , CH-40 01 Basel, Switzerland tel: 4 1- 6 1- 2 6 0-6 300; fax: 4 1- 6 1- 2 6 0-6 333 ... octanol-water partition coefficients J Pharm Sci 67:786–788, 19 78 16 M M Narurkar and A K Mitra Prodrugs of 5-iodo-20 -deoxyuridine for enhanced ocula...

Ngày tải lên: 10/08/2014, 00:20

... Ref 0 .24 0 .28 0.33 0. 42 0.53 0.53 0.58 0. 62 1.65 1.68 1.93 SSa SS SS SS SS SS EXTb EXT EXT EXT EXT 48 48 48 43 67 111 50 46 27 27 26 SS = steady-state method A constant concentration of drug is ... approach Table Ocular Volumes of Distribution ðVd Þ for Various Drugs Drug 2- Benzothiazolesulfonamide Ethoxzolamide 6-Hydroxyethoxy -2 - benzothiazolesulfonamide Phenylephrine Clonid...

Ngày tải lên: 10/08/2014, 00:20

... (h)a 4h Phakic Central 8.36 6.61 2.61 0.60 8.08 6 .49 2 .49 0.5 64 3. 54 3.79 1.27 0.339 1.39 2.11 0.695 0.158 8.38 6.61 2 .47 0. 646 3. 54 3.72 1.26 0.312 3.75 3. 84 1.35 0.303 2.29 2 .41 0.626 0. 146 Lens ... 2.97 (2.83) 0.1 54 (11.1) 210 (0.1 04) 0.084b (9.31)b 3. 34 (4. 33) 328 (0.093) 0 .42 1 (11.2) 3.98 (2.03) 4. 13 (4. 33) 0 .43 0 (10.3) 563 (0.131) 0.163 (12.9) 0.873 (5.22) 3.5...

Ngày tải lên: 10/08/2014, 00:20

... transport of 4-phenylazobenzyloxycarbonyl-L-Pro-L-Leu-Gly-L-Pro-D-Arg across rabbit colonic segments and Caco-2 cell monolayers J Pharmacol Exp Ther J Contr Rel 36: 25 37, 2 75: 114–119, 19 95 Copyright ... 64:1312–1316, 19 75 Robinson, J R., and Mlynek, G M Bioadhesive and phase-change polymers for ocular drug delivery Adv Drug Delivery Rev 16: 45 50 , 19 95 Salminen, L., and Urtt...

Ngày tải lên: 10/08/2014, 00:20

... applied ophthalmic drugs, Surv Ophthalmol., 26: 207–218 88 Mikkelson, T J (1984) Review: Ophthalmic drug delivery, Pharm Tech., 8:90–98 89 Lee, V H L (1985) Review: Topical ocular drug delivery recent ... segment of the eye, Biomaterials., 21 :64 9 66 5 131 Peyman, G A., and Ganiban, G J (1995) Review: Delivery systems for intraocular routes, Adv Drug Delivery Rev., 16: 107–...

Ngày tải lên: 10/08/2014, 00:20