... differentiable norm or a reflexive Banach space E with a weakly continuous duality a mapping Other investigations of approximating common fixed points for a countable family of nonexpansive mappings can ... 23 initiated the study of certain classes of nonlinear operators by means of the duality mapping Jϕ Following Browder 23 , we say that a Banach space E has a w...
Ngày tải lên: 21/06/2014, 11:20
... conserved cytosolic quality control pathways remains to be discovered The objective of this thesis is to get a better understanding of protein quality control in cytosol and further understand the mechanism ... al., 1998) The binding induces several factors; one of them being ubiquitin expression indicating its role in the regulation of the degradation syst...
Ngày tải lên: 10/09/2015, 15:54
A metabolomics approach to understand mechanism of heat stress response in rat
... triiodothyronine (T3) and thyroxine (T4) and the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), creatine kinase (CK) and lactate dehydrogenase ... unrestrained heat- acclimated rats Measurement of these variables without the confounding effects of restraint or handling has increased the validity of the rat as a model fo...
Ngày tải lên: 11/09/2015, 21:52
Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... and diseases such as type diabetes mellitus, obesity and the metabolic syndrome (30) In these conditions there is an elevation of both glucose and free fatty acid levels in the blood and an increase ... discontinuation of therapy HbA1c increased to 7.8 Discussion The results of this preliminary trial showed that ultra-low microcurrent has apparent therapeutic e...
Ngày tải lên: 26/10/2012, 09:39
Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc
... accumulation of propionyl-CoA (Fig 1) Addition of propionate to the glucose medium led to an increase of the propionyl-CoA level in the wild-type strain The methylcitrate synthase deletion strain showed ... formation of propionyl-CoA This observation readily explains the decreased propionyl-CoA levels found in cells grown on glucose/ acetate /propionate a...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: The mechanism of a-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase doc
... anchoring of a-carboxylate and a -amino group in the external aldimine defines automatically the positions of the a-proton and the side chain of any bound amino acid The lability of the a-proton ... from the amino group to the a-carbon atom of the quinonoid intermediate should go faster than the isotopic exchange of the proton in the active si...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
... outside the cells, before internalization, we investigated the role of plasma membranes (PM) in the transformation of MSSAE into a dimeric protein 125I-labelled MSSAE was incubated with isolated ... reconstituted in the presence of growing broblasts into the parent dimeric protein, which is internalized as a native-like dimeric RNase They also indicate for the...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Conservation of the egg envelope digestion mechanism of hatching enzyme in euteleostean fishes pot
... result of the formation of e-(c-glutamyl) lysine cross-links between subunit proteins of the envelope, mainly between inner layer subunit proteins [10] At the time of hatching of the embryo, the inner ... envelope One of the goals of the present study was to determine the cleavage sites of hatching enzyme on egg envelope proteins The natural subs...
Ngày tải lên: 06/03/2014, 02:20
Báo cáo khoa học: Transthyretin and familial amyloidotic polyneuropathy Recent progress in understanding the molecular mechanism of neurodegeneration pdf
... b-strands instead of eight, with the C and D strands and the intervening loop forming a large loop, exposing some hydrophobic residues in this region that are normally buried on the inside of the ... the protein [98] Dislocation of the C and D strands from their native edge region may result in the formation of a new interface involving A and B strands which...
Ngày tải lên: 07/03/2014, 10:20
Báo cáo khoa học: A steady-state modeling approach to validate an in vivo mechanism of the GAL regulatory network in Saccharomyces cerevisiae ppt
... to validate the mechanism of induction of GAL genes by galactose In each of the models, cytoplasmic Gal3 p is activated by galactose Further, Gal4 p dimerizes and interacts with the DNA to form the ... expression of GAL genes in response to galactose The GAL genetic switch The GAL regulatory network is composed of three regulatory proteins:...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo Y học: The mechanism of nitrogen monoxide (NO)-mediated iron mobilization from cells NO intercepts iron before incorporation into ferritin and indirectly mobilizes iron from ferritin in a glutathione-dependent manner pot
... isonicotinoyl hydrazone class as effective antiproliferative agents II The mechanism of action of ligands derived from salicylaldehyde benzoyl hydrazone and 2-hydroxy-1-naphthylaldehyde benzoyl hydrazone ... controls Apolactoferrin was from Calbiochem A polyclonal rabbit anti-(human ferritin) Ig was from Roche Diagnostics All other chemicals were of analytical reagent qual...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: Role of conserved residues within helices IV and VIII of the oxaloacetate decarboxylase b subunit in the energy coupling mechanism of the Na+ pump ppt
... that the < /b> Na+ binding of < /b> the < /b> decarboxylase < /b> (Km % mM) was dramatically affected by the < /b> S382A mutation We also investigated the < /b> stability of < /b> OadB with the < /b> S382A mutation in the < /b> presence of < /b> trypsin ... involving by R389 through lowering the < /b> pK of < /b> the < /b> tyrosine hydroxyl group The < /b> proton is delivere...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo khoa học: Catalytic mechanism of the primary human prostaglandin F2asynthase, aldo-keto reductase 1B1 – prostaglandin D2 synthase activity in the absence of NADP(H) pptx
... 128 8–1 298 ª 2011 The Authors Journal compilation ª 2011 FEBS Prostaglandin D2 synthase activity of AKR1B1 N Nagata et al Fig Overall views of the ternary complex of human AKR1B1–NADPH–PGH2 The ... the amino acid sequence of AKR1B1 also catalyzed both PGFS activity [3.6 nmolÆmin)1Æ(mg protein))1] in the presence of NADPH and PGDS activity [3.3 nmolÆmin)1...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates ppt
... using surface plasmon resonance analysis to determine the role of residue 71 in collagen binding The elucidation of the mechanism of structural protein substrate recognition in serine proteases should ... compilation ª 2009 FEBS 5643 Substrate recognition mechanism of Streptomyces trypsin into the NdeI–HindIII gap of pTONA5a to construct the expressio...
Ngày tải lên: 16/03/2014, 00:20
A study in the growth mechanism of silicon nanowires with or without metal catalyst
... Metal- assisted growth of SiNWs A basic aspect of the VLS mechanism is the metal particle acting as a catalyst for the anisotropic growth of SiNW with a crystalline structure A catalyst particle ... substrate (Fig 2B a) , a liquid metal Si alloy will be formed With more and more Si atoms added, the Si content in the If the growth with a...
Ngày tải lên: 16/03/2014, 15:09