Rapid Clinical Pharmacology

... 17:151-183 Maxwell S 1999 Emergency management of acute myocardial infarction British Journal of Clinical Pharmacology 48: 284-298 Manhapra A, Borzak S 2000 Treatment possibilities for unstable angina ... receiving ramipril mg x 2/d, started 3-10 days after a myocardial infarction in 2006 patients with only clinical signs of heart failure.28 Indeed, in addition to these drugs, most pati...

Ngày tải lên: 18/10/2013, 00:15

... in removing salt and water that any drug can achieve is related to its site of action, and it is clinically appropriate to rank diuretics according to their natriuretic capacity, as set out below ... controlled conditions and should not be taken to represent the average fractional sodium loss during clinical use High efficacy Frusemide (furosemide) and the other (loop) diuretics can cause u...

Ngày tải lên: 24/10/2013, 19:15

... syndrome similar to vitamin K deficiency.3 Bishydroxycoumarin (dicoumarol) was introduced into clinical practice as an anticoagulant in the 1940s and other structurally related vitamin K antagonists ... due to intracranial haemorrhage Management of bleeding or over-anticoagulation is guided by the clinical state and the INR:7 • Haemorrhage threatening life or major organs In addition to b...

Ngày tải lên: 24/10/2013, 19:15

... These interactions can be clinically important Ingestion should be separated by hours Ascorbic acid increases absorption (see above) but its use (200 mg/day) is not clinically important in routine ... Medicine 341:1509-1519 Castle W B 1966 Treatment of pernicious anaemia: historical aspects Clinical Pharmacology and Therapeutics 7: 347 Ferner R E et al 1989 Drugs in donated blood Lancet 2...

Ngày tải lên: 29/10/2013, 02:15

... lymphoblastic leukaemia Other cytotoxic agents in clinical use include procarbazine, dacarbazine, hydroxyurea (hydroxycarbamide) Chemotherapy in clinical practice DRUG USE ANDTUMOUR CELL KINETICS ... specific for chronic granulocytic leukaemia; clinical trials support its efficacy in this disease 618 • Agents that promote apoptosis are being developed for clinical use Chemoprevention...

Ngày tải lên: 29/10/2013, 02:15

... ulcerhealing course is weeks Cimetidine Cimetidine was the first H2 receptor antagonist to be used in clinical practice It is rapidly absorbed from the gastrointestinal tract and its plasma t1/2 is ... the final common pathway for acid production Omeprazole was the first preparation to be used in clinical practice and esomeprazole, lansoprazole, pantoprazole and rabeprazole were subsequen...

Ngày tải lên: 08/11/2013, 01:15

... mineral spring water, and for horse racing 640 the treatment of hepatic encephalopathy (see Chapter 33) Osmotic laxatives are frequently used to clear the colon for diagnostic procedures or surgery ... bacteria including Shigella and Salmonella spp, viruses including the Norwalk family, and parasites (particularly Giardia lamblia) have also been implicated Recognition that transmission is a...

Ngày tải lên: 08/11/2013, 01:15

Ngày tải lên: 08/11/2013, 01:15

... reading Clinical Pharmacology The world of clinical pharmacology has greatly changed since 1957 when I took up my pen, and I wish my successors well D R Laurence, Professor Emeritus of Pharmacology ... a good remedy sometimes to use nothing.' Hippocrates 460-355 B.C CLINICAL PHARMACOLOGY P N Bennett MD FRCP Reader in Clinical Pharmacology, University of Bath, and Consultant P...

Ngày tải lên: 15/12/2013, 12:15

... not enough could be obtained to provide supplies for clinical trial In 1948 cortisone was made from bile acids in quantity sufficient for clinical trial, and the dramatic demonstration of its ... syndrome Lancet 357: 783-791 English J et al 1983 Diurnal variation in prednisolone kinetics Clinical Pharmacology and Therapeutics 33: 381 Freidy J F 1988 Reactions to contrast media and ste...

Ngày tải lên: 15/12/2013, 12:15

... and crystalline suspension, it is not expected that doctors or patients would vary the formulation prescribed The important thing is for the doctor to get to know well a range that will serve ... glucose uptake in the brain during episodes of hypoglycaemia that trigger a symptomatic and neuroendocrine response in patients with elevated levels of HbAlc (see Boyle et al 1995, in Guide to Furthe...

Ngày tải lên: 15/12/2013, 12:15

... Lancet 345: 170-175 Relston S H 1992 Medical management of hypercalcaemia British Journal of Clinical Pharmacology 34:11-20 Seeman E 2002 Pathogenesis of bone fragility in women and men Lancet ... 25hydroxylation Advantages of alfacalcidol and dihydrotachysterol include a fast onset and short duration of clinical effect (days) which renders them suitable for rapid adjustment of plasma c...

Ngày tải lên: 15/12/2013, 12:15

... the pharmaceutical industry Principal sources of guidance 37 Ian Dodds-Smith A professor of clinical pharmacology who has made special studies of prescribing and patient information writes: 'What ... Ernst E, Thompson J 2001 Heavy metals in traditional Chinese medicines: a systematic review Clinical Pharmacology and Therapeutics 70: 497-504 Ferner R E 2000 Medication errors that have...

Ngày tải lên: 24/12/2013, 18:15

... they not create dependence, (2) the patient does not increase the dose and create dependence, (3) they are not used as an unwitting source of supply to addicts To many such drugs special prescribing

Ngày tải lên: 24/12/2013, 18:15

... Science, medicine and clinical pharmacology British Journal of Clinical Pharmacology 40:1-9 Breckenridge A1999 Clinical pharmacology and drug regulation British Journal of Clinical Pharmacology 47: ... Ethics and law in clinical pharmacology British Journal of Clinical Pharmacology 27: 715-722 Reidenberg M M 1999 Clinical pharmacology: the scientific basis of therap...

Ngày tải lên: 24/12/2013, 18:15