Identi cation of relevant patterns in spectral signatures

... 4) For the amylopullulanase from Thermococcus hydrothermalis (Q9Y8I8_THEHY), the numbering of the mature enzyme is used [23] The two GH -57 catalytic residues – Glu291 and Asp394 (Q9Y8I8_THEHY) ... data) Therefore, in attempt to provide the first elements towards the understanding of the functionality of the potentially valuable, heat stable GH -57 enzym...

Ngày tải lên: 19/02/2014, 12:20

... Ye RD (19 97) The N -formyl peptide receptor: a model for the study of chemoattractant 777 Functional domains in FPRL1 10 11 12 13 14 receptor structure and function Pharmacol Ther 74, 73 10 2 Le ... the second intracellular loop of FPRL1 with the corresponding part of FPR (A) Chimera H contains the N-terminus and a segment between the fourth TM and the thi...

Ngày tải lên: 16/03/2014, 18:20

... lysine-binding-site-mediated interaction between plasmin and antiplasmin Molecular modelling of the C-terminal portion of antiplasmin The amino- acid sequence of the C-terminal 40 residues in antiplasmin ... lysine-binding-site-dependent interaction between plasmin and antiplasmin in detail by constructing seven single-site mutants of antiplasmin Fig Computer mo...

Ngày tải lên: 17/03/2014, 03:20

... articles indexed in MEDLINE at the end of 2004 (14,785,094 articles) The following sections explain in detail off-/on-line processing for the text retrieval system for MEDLINE 3.1 Off-line processing: ... entry and examine the effects of using predicate argument structures and ontological identifiers The need for the discovery of relational concepts has been i...

Ngày tải lên: 17/03/2014, 04:20

... than the other compounds (Fig 6) In this way, amino acid residues of different segments of NADP-ME2 swapped in the construction of the chimeras are involved in the fumarate activation of the pyruvate ... of CoA or acetyl-CoA The results are presented as the percentage of activity in the presence of the effectors in relation to the activity measure...

Ngày tải lên: 23/03/2014, 04:20

... establish a three -domain- structure for the a- subunit consisting of the N-terminal carboxyltransferase domain and the C-terminal biotin-binding domain which are connected by the association domain ... formation between the a- and c-subunits and dissociation at acidic pH A detailed analysis of the interaction of the C-terminal domain of the c-subunit...

Ngày tải lên: 23/03/2014, 13:20

... obtained the Master of Engineering degree in July 2004 She then attended McMaster University pursuing further studies in the Department of Electrical Engineering and completed the degree of Master ... edges are the [MK − (K + L)] vectors {ηm } involved in the principal minor Now, since the determinant of the rank deficient matrix P ⊥ Σr (P ⊥ )H H H represents the...

Ngày tải lên: 22/06/2014, 23:20

... set, data cleansing and preprocessing, data reduction and projection, choosing data mining task, choosing data mining algorithm, data mining, interpreting the mined patterns and consolidating ... livestock genomics for integrative data analysis following the principles of data mining and knowledge discovery and (ii) demonstrating the application o...

Ngày tải lên: 25/11/2015, 13:26

... sensitivity of the original search strategy for membrane proteins that are related to AChRs only by function Candidate LGICs retrieved by the search strategy Fig Hydropathy profiles of four proteins ... symporters is reflected in a characteristic pattern of peaks in their hydropathy profiles (A) The hydropathy profile of a rat dopamine symporter reveals a pair o...

Ngày tải lên: 17/03/2014, 23:20

... GAG AAT CTC CTC CTC CTC TGC TGC AAG GCA GGT CTC TCA TGA CTC GGA GAA GAA GGA GAG CAA CTG CAA ATA GAA GAA TTG TGG GAA GGA GGA GAG TTG TGA CCG GGT GCG ATC TCA CAT GAG TCC TTC TTC TCC CTC TCC CAC ... GGT CTT CTC ATG TGA TCA ACA GTG GTC TCA CGG TTG TGG ACA ATG CTA CAA CCA TGC TAT CAA TCG AAG TCA CAT TAC ACA GGT ATA TGA GCT AAG CTG TTG CTG GCA CTT CCA TGT GAT TTG CCA CTC ATT ATG CGA ATG (lpxX ... G...

Ngày tải lên: 18/02/2014, 14:20

... identify the site of action of the fatty acids in the plasmin molecule, the amidolytic activity of two truncated plasmin variants was examined (Fig 8) Miniplasmin (des-kringle 1-4 plasmin) contains the ... parameters of plasmin in the presence of fatty acids The values of kp and Km were determined from the amidolytic assay of plasmin...

Ngày tải lên: 18/02/2014, 17:20

... aragonite crystals [4–7] We therefore examined proteins contained in aggregates within the otolith matrix and identified a protein contained in the HMW protein glycosaminoglycan aggregate that also ... digestion of genomic DNA contamination in the total RNA was confirmed by lack of amplification of a b-actin mRNA fragment by PCR using a pair of primers (5¢-ATCACCAT...

Ngày tải lên: 18/02/2014, 17:20

... patterns of hydrophobins HFBIII of H jecorina and T longibrachiatum, and SRH1 and HFB1 of T atroviride, involving signal peptides, Kex2type processing, and C-terminal amino acid cleavage (Table 2) In ... compilation ª 2007 FEBS T Neuhof et al Trichoderma hydrophobins Fig Intact-cell MALDI-TOF mass spectra of mycelia and spores of Trichoderma strains The mass...

Ngày tải lên: 19/02/2014, 02:20

... strain was grown in media lacking leucine The other strains were grown in media containing leucine Complementing abilities of LEU2, UTR1 and YEF1 for the growth defects of the pos5 mutant To confirm ... using recombinant protein expressed in E coli We also confirmed that Utr1p, initially identified as an ATP-NAD kinase [1], was in fact an ATP-NADH kinase Thus, the three is...

Ngày tải lên: 20/02/2014, 01:20

... inhibitor binding Subdomain I (N-terminal) contains the zinc-binding site, which faces into the deep cleft formed by the two subdomains connected at the base of the cleft The hinge-bending motion ... importance of key active-site residues of ACE2 through site-directed mutagenesis, with the aim of providing practical evidence for their role in substrate binding ⁄ hydrolysis...

Ngày tải lên: 20/02/2014, 01:20