The role of serum amyloid a in atherosclerosis

... Bhagwat SV, Biswas G, Anandatheerthavarada HK, Addya S, Pandak W & Avadhani NG (199 9) Dual targeting property of the N-terminal signal sequence of P450 1A1 Targeting of heterologous proteins to ... open N-terminal signal domain is critical for protein targeting to the ER (Fig 2D) In contrast to the targeting of CYP 1A1 requiring N-terminal truncation, w...

Ngày tải lên: 18/02/2014, 16:20

... stable supply of knowledge and skills in high need areas Increase the size, diversity of skills and productivity of the labor force Dimensions of Social and Economic Value Regional public institutions ... business Best Practice Highlights Slippery Rock University Regional Learning Alliance – workforce development and training/collaborations with business and...

Ngày tải lên: 21/02/2014, 01:20

... observed in weaker binders Evaluation of the VH ⁄ VL interaction strength To evaluate the VH ⁄ VL interaction strength of these 36 clones, phages were used to infect a nonsuppressing strain, HB2151, ... strong VH ⁄ VL binder, to describe the relationship, and also to identify key residues in determining the interdomain interaction stren...

Ngày tải lên: 07/03/2014, 12:20

... Claire Cardie, Vincent Ng, David Pierce, Chris Buckley Examining the role of statistical and linguistic knowledge sources in a general-knowledge que stion answering system In Proceedings of the 6th ... periments with Open-Domain Textual Question Answering In the Proceedings of the 18th International Conference on Computational Linguistics (COLING-2000), pages 292298, 2000 Fr...

Ngày tải lên: 08/03/2014, 05:20

... 5.2.) Hypothesis 2: When the gift recipient s perception of prior attitude toward a brand is neutral and the giver -recipient relationship is strong, then the gift recipient s post -brand attitude ... level of recipient s perception of prior brand attitudes - Hypothesis 7a: The recipient s post brand attitude change is greater when receiving the...

Ngày tải lên: 14/03/2014, 14:20

... bridging the A and G b-strands of the I27 protein during the main unfolding barrier.[39] To further validate this view and gain insight into the role of solvent hydrogen bonds in protein unfolding, ... separating b-strands In Figure B, we define the pulling coordinate for the A and G b-strands as the distance between the first amino acid of strand...

Ngày tải lên: 22/03/2014, 18:20

... that both ADAM10 and TACE are involved in the shedding of APP, neither ADAM is involved in the shedding of ACE Furthermore we show that APMA can distinguish between the shedding of ACE and APP ... would appear that ADAM10 and TACE are not critically involved in the shedding of ACE APMA has been reported to induce the shedding of a number of pro...

Ngày tải lên: 30/03/2014, 14:20

... level in Zambia served in the capacity of district managers of health programmes The finding that the nurses in Sudan were less involved in planning of activities (15.2% in polio and in measles) ... in AFP surveillance On the other hand, in Zambia, nurses and midwives were involved in the full range of functions for SIAs and AFP surveillanc...

Ngày tải lên: 18/06/2014, 17:20

... coordinated the study, participated in data cleaning and data analysis, and was the lead author on this paper ED performed data cleaning and data analysis SM contributed to data analysis, writing of ... our research provides valuable quantitative information demonstrating the critical role that Indian generic pharmaceutical manufacturers play in the global treatment o...

Ngày tải lên: 20/06/2014, 08:20

... when patients have synchronous distant metastasis Crane et al., have reported that pelvic irradiation has a palliative role in treating rectal cancer liver metastasis [18] Eighty patients with synchronous ... spread of colorectal cancer occurs mainly via the portal system and the incidence of isolated liver metastasis in rectal cancer is seven times higher th...

Ngày tải lên: 09/08/2014, 09:20

... 1.9 11.3 ± 2. 1 12. 1 ± 2. 0 11.9 ± 1.4 2. 2 – 3.1 2. 2 – 3.1 2. 2 – 2. 8 2. 5 – 3.4 2. 2 – 3.1 2. 2 – 2. 8 2. 2 – 3.1 2. 2 – 3.7 2. 5 – 3.1 1–1 0–1 0–1 0–1 Overall Mean 15 15 10 2. 2 – 3.7 2 4 37.5 ± 4.0 11.4 ... PCV2a and PCV2b in the field Virus Res 20 07, 1 32: 201 -20 7 Page of 11 (page number not for citation purposes) Acta Veterinaria Scandinavica 20 09, 51:13 10...

Ngày tải lên: 12/08/2014, 18:22

... optimal care of trauma patients As early as 1966 the role of physicians staffing emergency rooms in the care of trauma patients was discussed as an important element in preventable trauma death ... training allows exposure to trauma only as part of their general EM training, particularly if a separate trauma team responds for trauma activations In smaller...

Ngày tải lên: 13/08/2014, 23:20

... facilitating its growth and hence angiogenesis is pro-atherogenic The final stage in the development of an atheroma involves the rupturing of a plaque Plaque rupturing involves the erosion of the ... important for the binding of SAA1 to components of the extracellular matrix (Uhlar and Whitehead 1999) The only reported role of the C-terminal domain is its fac...

Ngày tải lên: 10/09/2015, 15:51

... not a major acute phase protein and has not been regarded as a biomarker of CAD 1.4 Endothelial proinflammation 1.4.1 Endothelial proinflammation in atherosclerosis Ross proposed in 1999 that atherosclerosis ... acute inflammation, its an-inflammatory function could be reduced 15 1.2.2 A biomarker of atherosclerosis The characterization of SAA as both an inflammato...

Ngày tải lên: 14/09/2015, 13:15

... minimization of tissue damage and promotion of healing (Baranova et al., 2010; Sandri et al., 2008) In the event of a tissue injury, the acute phase response initiates the activation of a cascade, ... indication of the involvement of macrophages in plaque rupture (Boyle, 2005) 1.3 Serum Amyloid A (SAA) SAA is a 12.5kDa acute phase reactant which plays a...

Ngày tải lên: 12/10/2015, 17:36