... role in protein stability [8], and their involvement in interactions with cations offers new perspective in the analysis of the contribution of ions as cofactors in protein folding [38] and in ... those observed for the wild-type, indicating the involvement of Glu53 and Asp287 in the interaction with the cation (Fig 1E,F) The regain of aromatic chirality at 295 nm and in the 260–270 nm region ... pfLamA in the native state, independently of their interaction with calcium The role of electrostatic interactions in protein stability has been widely investigated and the stabilizing effect of
Ngày tải lên: 30/03/2014, 04:20
... catenin. The binding of Wnt to frizzleds inhibits the activity of glycogen synthase kinase 3β (GSK-3β) and thus stabilizes β-catenin in the cytoplasm. β-catenin accumu- lates in the cytoplasm and ... action inactivates RPTP β/ζ, which results in an increase of the phosphorylation of β-catenin on its tyrosine residues (Tyr-Pi) and the release of β-catenin from cadherins. (B) In the absence of ... Retinoid acid accelerates the development of the alveolar tree and promotes the expression of sur- factant proteins and enzymes for the synthesis of surfac- tant lipids [25]. On the other hand,
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "The role of ATP and adenosine in the control of hepatic blood flow in the rabbit liver in vivo" pps
... Diagram of silastic H-shaped prosthesis inserted into the portal vein and the inferior vena cava of the in vivo rabbit modelFigure 1 Diagram of silastic H-shaped prosthesis inserted into the portal ... by relat- ing the readings to the wet weight of the liver, determined at the end of each experiment. The "buffering capacity" of the HA was expressed in % as: [Increase in HA flow ... intra-portal injection of (a) ATP and (b) adenosine on changes in hepatic arterial flow (∆ HAF) in vivoFigure 3 The effect of intra-portal injection of (a) ATP and (b) adenosine on changes in hepatic
Ngày tải lên: 13/08/2014, 13:20
The role of cyr61 and LASP1 in growth and metastasis of human hepatocellular carcinoma
... p53. In conclusion, this study provides insights into the roles of two interesting genes which are involved in tumor metastasis and growth. The data also strengthens the understanding of the effect ... protein that is phosphorylated by FAK, binds to vinculin and crosslinks actin stress fibers and tethers them to focal adhesion sites Zyxin is an α-actinin- and stress-fibre-binding protein ... to actin, building the connection to the cytoskeleton (Partridge and Marcantonio 2006) For instance, the integrin-binding proteins paxillin and talin recruit focal adhesion kinase (FAK)
Ngày tải lên: 13/09/2015, 19:46
The power of identity and ideology in language learning,
... volumes containing empirical research on multilingual language acquisition, language contact and the respective roles of languages in contexts where the languages are not cognate and where the scripts ... and cultural ideologies, and (b) is in line with Darvin and Norton’s (2015) call to examine the nexus of identity, ideology and capital when considering the investments of language learners In ... “traditional notions of identity elide the significant role of fear, desire, anger and other powerful feelings in shaping the forms of action” (p 23), adding and emphasizing the need to examine “how identities
Ngày tải lên: 14/05/2018, 15:38
Fathers today: Design of a randomized controlled trial examining the role of oxytocin and vasopressin in behavioral and neural responses to infant signals
... behavioral and neural underpinnings of fatherhood In the current study, we will examine the effects of oxytocin and vasopressin administration on parenting behavior and the neural and behavioral ... are instructed to engage in their usual routines of play No play material is provided during the first five minutes of the interaction After min, the researcher will hand the father a bag of toys ... distribution of 12 neutral and 12 threatening videos during the first half of the task, and 12 neutral and 12 threatening videos during the second half of the task Prior to the onset of the task,
Ngày tải lên: 10/01/2020, 12:28
Sequential expectations the role of prediction based learning in language
... Christiansen, J B Tomblin ⁄ Topics in Cognitive Science (2010) standard AGL designs in the language- like nature of string-sequences, the smaller number of training exemplars, and the greater transparency ... task scores) indicates distinct differences during nonadjacency learning Thus, there are contrasts in the shape of the statistical learning trajectory, final training performance, and the response ... processing Language and Linguistics Compass, ⁄ 4, 647–670 King, J., & Just, M A (1991) Individual differences in syntactic processing: The role of working memory Journal of Memory and Language,
Ngày tải lên: 12/10/2022, 20:48
The role of learning and development in
... shaped by ontogeny A growing bulk of work on the evolution of language has focused on the role of learning – often in the guise of “cultural transmission” – in the evolution of linguistic communication ... Mutation of the languages was accomplished in the same way, and winning grammars were again selected on the basis of their learnability Runs of this simulation were halted after the winning language ... heads of phrases: The particular word in a phrase that determines the properties and meaning of the phrase as a whole (such as the noun boy in the noun-phrase ? ?the boy with the bicycle’) Across the
Ngày tải lên: 12/10/2022, 21:26
THE ROLE OF RELIGION AND SPIRITUALITY IN PSYCHOTHERAPY SOWK 618
... the impact of these on the helping process An understanding of psychodynamic, philosophical, theological and sociocultural understandings of the interface between psychotherapy and religion and ... spirituality Included in this understanding is an awareness of the variety of meanings of different forms of clients’ spiritual and religious expression Values A dedication to the values and ethics of the ... appropriate This includes the ability to understand, respond to, and incorporate clients’ spiritual and/ or religious issues in interviewing, assessment, and intervention and determine whether these issues
Ngày tải lên: 18/10/2022, 04:04
The Role of Colleges and Universities in Neighborhood Real Estate
... as the needs of the communities in which they reside Despite the tension that often accompanies university-driven real estate development, it is possible to find the point where the goals of the ... from the experiences of the five institutions Interviews regarding Old Dominion University were conducted in February 2003; interviews regarding the University of Notre Dame were conducted in May ... depends on the goals and motivation of the institution as well as the opportunities that exist within the neighborhood Revitalization strategies, as carried out by the institutions included in the study,
Ngày tải lên: 30/10/2022, 16:10
The Role of Colleges and Universities in Neighborhood Real Estate_2
... as the needs of the communities in which they reside Despite the tension that often accompanies university-driven real estate development, it is possible to find the point where the goals of the ... from the experiences of the five institutions Interviews regarding Old Dominion University were conducted in February 2003; interviews regarding the University of Notre Dame were conducted in May ... depends on the goals and motivation of the institution as well as the opportunities that exist within the neighborhood Revitalization strategies, as carried out by the institutions included in the study,
Ngày tải lên: 30/10/2022, 16:12
Assessing the role of determinants and evfta in shaping vietnams wood export to eu countries insights from a gravity model analysis
... countries and how each of them plays the role in altering the exporting data, using the gravity model After analyzing and explaining results, suggestions of policy implications and business strategies ... that the distance needed for transportation was the main factor affecting the volume of trade in the wooden product sector The study also found that a number of other variables, including the ... variables, including the size of the importing country, relative prices, the level of development and the availability of wood in the exporting country, and the overall volume of trade between countries,
Ngày tải lên: 03/06/2023, 18:55
(Tiểu luận) assessing the role of determinants and evfta in shaping vietnams wood export to eu countries insights from a gravity model analysis
... countries and how each of them plays the role in altering the exporting data, using the gravity model After analyzing and explaining results, suggestions of policy implications and business strategies ... analyzing the effects of economic factors, such as the size of the economies and the level of trade barriers But other elements, like the quality of the wood products and the accessibility of trade ... variables, including the size of the importing country, relative prices, the level of development and the availability of wood in the exporting country, and the overall volume of trade between countries,
Ngày tải lên: 30/01/2024, 05:09
The role of nature in cancer patients'' lives: A systematic review and qualitative meta-synthesis
... between the themes This informed the final theoretical synthesis of findings into overarching, analytical themes, or ‘core themes’ [47] These core themes were developed in relation to the meta-synthesis’ ... for assessing the quality of included studies, and they were also used as a guide for reporting findings in this present meta-synthesis The strength of the COREQ guidelines lies in outlining three ... from the bed areas’ and the ‘use of artwork depicting scenes of nature? ?? [11] Exploration, inner and outer excursions Overlapping the previous two themes of connecting and being elsewhere was the
Ngày tải lên: 06/08/2020, 07:17
Research for a Future in Space: The Role of Life and Physical Sciences ppt
... Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities The Council... science and technology and to their ... the Report In May 2009, the NRC Committee for the Decadal Survey on Biological and Physical Sciences in Space began a series of meetings initiated as a result of the following language in the ... an understanding of biological and physical processes, as well as their intersections, in the presence of a range of reduced gravity conditions. The examples presented in the following pages
Ngày tải lên: 29/06/2014, 09:20
Báo cáo khoa học: "Short-term variations and long-term changes in oak productivity in northeastern France. The role of climate and atmospheric CO 2" pot
... oak (+40%) The growth increase in the ’young’ rings (< 60 years) of sessile oak was + 81%, and that of young rings of pedunculate oak was + 49% The corresponding increase in the ’old’ rings (> 65 ... curves for the growth indices of the ’young’ (< 60 years) and the ’old’ (> 65 years) rings (cambial age) In the final stage, the curve of the growth indices IC0 was modelled according to the available ... III and IV) The case of July appears somewhat disconcerting because the related parameters and the from years y, y- and y- on the hand, and years y- and y- on the other, can be given opposing
Ngày tải lên: 08/08/2014, 19:21
Báo cáo y học: "The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells" doc
... major role in the prevention of autoimmunity and pathological immune responses Their involvement in the pathogenesis of chronic arthritis is controversial, however, and so we examined their role in ... arthritis, another major advantage of the AIA model is that the time point of induction of arthritis is known, allowing manipulation of CD4+CD25+ Treg cell number in vivo at defined stages in the disease ... rest of the body was determined using a γ-counter Thereafter, the total radioactivity recovered per animal was calculated by adding the counts of the organs and the rest of the body (a) The proportion
Ngày tải lên: 09/08/2014, 06:22
The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf
... accumulating school savings may have effects apart from financing school. Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college. Further, ... for their youth. Youth savings. Youth were asked in 2002 whether they had a savings or bank account in their name. If they had an account, they were also asked whether they were saving some of ... None of the existing research examines the effect of youth savings on college attendance, and only one study examines the relationship between parent school savings and college attendance. Theoretical...
Ngày tải lên: 15/03/2014, 10:20
The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx
... & Lynch, K. (1999).Offeringa hand to pragmatic understanding: The role of speech and gesture in comprehension and memory. Journal of Memory and Language, 40, 577–592. Lansing, C. R., & McConkie, ... gestures and facial cues seeking the most infor- mative cue according to the content of the lecture. The results of the questionnaire revealed that the majority of those who reported they paid ... minimal reference to the outline during recording. The first part of the lecture covered definitions of terms and a brief history of ceramics, which tended to be done in narrative form. Most of...
Ngày tải lên: 10/03/2014, 05:20
Tài liệu The Role of Public Regional Universities in Community and Economic Development doc
... University Regional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... Programs and Initiatives Business accelerators and/ or entrepreneurial initiatives Linking teaching and research to business opportunities Collaboration with local business and industry Small Business ... substance Stimulate intellectual growth and individual productive capacity Ensure a stable supply of knowledge and skills in high need areas Increase the size, diversity of skills and productivity of the labor...
Ngày tải lên: 21/02/2014, 01:20
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