Estrogen receptor a mediated long rang chromatin interactions at the ret gene locus in breast cancer
Estrogen receptor a mediated long rang chromatin interactions at the ret gene locus in breast cancer
... ATCAAACTGGAGGGAGCAGA B TCAGACAGTGCCAGTGGAAG E GCCAGTGGAAGTGTAAGTTGG B TCGGGACACAGCATCATAA F GACACTGACAGGATTTACCATACTGTTGG B TCGGGACACAGCATCATAA G GGTCAAGTGTTCCCGTGATCCTACTG B TCGGGACACAGCATCATAA H CACAGGGAAATGCAGCACAGCTAG ... 23 AB BC BD BE BF BG BH BI BJ BK IJ A CATGGGAGAAAGATGTAGTCTGGGAGAC B CTCTTTCGGGACACAGCATCATAATC B CTCTTTCGGGACACAGCATCATAATC C GAAAGGACAGAGAAGGTGCCAGTTG B TTCGGGACACAG...
Ngày tải lên: 05/10/2015, 21:29
AP 2 regulates estrogen receptor mediated long range chromatin interactions and gene transcription
... Yong EL, Sung WK, Cheung E (20 11) AP- 2gamma regulates oestrogen receptor- mediated long- range chromatin interaction and gene transcription The EMBO journal 30: 25 69 -25 81 Chng KR, Chang CW, Tan ... association of AP- 2 and FoxA1 with ERα -mediated long- range chromatin interactions 107 CHAPTER 4.1 4 .2 4.3 4.4 DISCUSSIONS 109 Exploring potential determinant...
Ngày tải lên: 09/09/2015, 10:20
Báo cáo khoa học: "A biologically competitive 21 days hypofractionation scheme with weekly concomitant boost in breast cancer radiotherapy feasibility acute sub-acute and short term late effects" pot
... Guenzi et al.: A biologically competitive 21 days hypofractionation scheme with weekly concomitant boost in breast cancer radiotherapy feasibility acute sub -acute and short term late effects Radiation ... appear interesting, with reasonably good feasibility in terms of acute toxicity [11,12] The purpose and primary endpoint of this study was...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: An estrogen receptor a suppressor, microRNA-22, is downregulated in estrogen receptor a-positive human breast cancer cell lines and clinical samples pptx
... 5¢-UCAUCGCAUUCC UUGCAAAdTdT-3¢, antisense strand 5¢- UUUGCAAGGAAUGCGAUGAdTdT-3¢; ERa siRNA #3 sense strand 5¢- GGAGAAUGUUGAAACA CAAdTdT-3¢, antisense strand 5¢- UUGUGUUUCAA CAUUCUCCdTdT-3¢ The transfection ... that miR-22 is frequently downregulated in ERa-positive human breast cancer cell lines and clinical samples In addition, further functional studies showed that E...
Ngày tải lên: 22/03/2014, 21:20
Dual activation of estrogen receptor a and aryl hydrocarbon receptor by the prenylflavone, icaritin restrict breast cancer cell growth and destabilize estrogen receptor a protein
... Despite the availability of therapies targeting estrogen and growth factor signaling pathways, the incidence and mortality of breast cancers have not decline at the same rate as other major causes of ... 36 1.8 Icaritin and cancer cell proliferation 1.8.1 Icaritin and cancer cell proliferation Herba Epimedii is officially listed in China as an herb that p...
Ngày tải lên: 04/10/2015, 17:05
Báo cáo khoa học: Contributions to catalysis and potential interactions of the three catalytic domains in a contiguous trimeric creatine kinase doc
... Taq HS polymerase (Takara USA, Santa Ana, CA, USA) was performed to fill in the sticky ends and add adenine nucleotide overhangs before ligating the individual domains into the TOPO vectors using ... essentially allowing only one of a set of interacting active sites to complete a catalytic cycle at a time Further understanding of catalysis and the interactio...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Vps4 regulates a subset of protein interactions at the multivesicular endosome doc
... GCCCATATTCGTCGACGCGCTAACAGGTACCAGAGGAGAAGGAGAGAGCGAAGCAAGTAG GGGCGGATCCTCTGCTTTTCTTTATC CTGGACACAGCCACGCAGTATACAGCATACTATAACGG CCGTTATAGTATGCTGTATACTGCGTGGCTGTGTCCAG CCTAAGTCGAAGGATTTGAAGCACTTGGAAAGTGAAG CTTCACTTTCCAAGTGCTTCAAATCCTTCGACTTAGG ... Vps4 Upstr F Vps4 SalI R Vps4 SalI F Vps4 Dstr R YEE F YEE R IRA F IRA R CGCTGCAGTAAGAGCAGTAAACCCG GAGAATCAGTGTCGACTTCATCTATAAAAATAATAGAAGGTT...
Ngày tải lên: 23/03/2014, 09:20
báo cáo khoa học: "CCR9-CCL25 interactions promote cisplatin resistance in breast cancer cell through Akt activation in a PI3K-dependent and FAK-independent fashion" pptx
... participated in its design and coordination and helped to draft the manuscript All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests ... part was noted Discussion GISTs are uncommon tumors originating from the interstitial cells of Cajal, which are pacemaker cells regulating autonomic motor activity in the ga...
Ngày tải lên: 09/08/2014, 01:24
A study on group discussion and its impacts on speaking ability of the non major students at the post elementary level in military science academy
... by information about the participants The study implementation is outlined along with information about data collection instruments used Finally, details of the nature of the data this study has ... is a reason why the Ministry of Education and Training needs to innovate the way of the second language teaching by applying the communicative approach in teachin...
Ngày tải lên: 07/09/2013, 13:02
Slide a study on group discussion and its impacts on speaking ability of the non major students at the post elementary level in military science academy
... Department at MSA - Nature of group work - Relationship between group work and individual presentation Objectives of the study contribute more theory to the understandings of group discussion find ... Number of participants in a group: Number of groups: ( No planning groups & Pre-planning groups) Records: All the group discussions and the indiv...
Ngày tải lên: 29/01/2014, 10:33
Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx
... showing it to be the aldosterone synthase of the guinea pig It was interesting to note that CYP11B2 of the guinea pig had a considerably higher enzymatic activity in terms of 11b-hydroxylated ... 11bhydroxylase activity of CYP11B1 was strongly reduced (Fig 5), whereas that of the aldosterone synthase was basically unaffected, while the 18-hydroxla...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... revealed another important PtdIns3P effector in endosomal tethering and fusion, namely EEA1, a protein that contains a Rab5 binding domain and a FYVE domain at its C-terminus, and a distinct Rab5 ... Flamingo, a determinant of planar cell polarity through the noncanonical Wnt signalling pathway, accumulates in the cytoplasm instead of translocating to polarized membrane do...
Ngày tải lên: 06/03/2014, 01:23
Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx
... Jolla, CA, USA) with pET2 8a( +)-wild-type Ec DosH as a template and using the following respective 5¢-sense primers: 5¢-gatga gtcgggagACCcagctggagaaaaaag-3¢, 5¢-gatgagtcgggagTTTcag ctggagaaaaaag-3¢, ... auto-oxidation [5], whereas Ala and Asn substitutions at Asp40, an amino-acid residue that interacts via two water molecules with the proximal ligand His77, markedly increased...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx
... observation of the first colonies in hematopoietic colony assays [55 ] The hematopoietic transcription factors SCL and GATA-2 were also expressed in these cells between days and 21 of differentiation ... indicated that the placenta acts as an additional extramedullary hematopoietic organ during embryonic and fetal development [52 ,53 ] Hematopoietic precursors found...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: A decade of Cdc14 – a personal perspective Delivered on 9 July 2007 at the 32nd FEBS Congress in Vienna, Austria pdf
... promoting CDK inactivation A question that arises from the observation that at least two pathways control Cdc14 localization is why budding yeast utilizes two pathways rather than one to regulate Cdc14? ... the metaphase–anaphase transition, Separase, a protease that triggers the separation of sister chromatids at the metaphase–anaphase transition [46] also regulates cycl...
Ngày tải lên: 23/03/2014, 06:20