Development and application of mass spectrometry based proteomics technologies to decipher ku70 functions

... describes development and application of mass spectrometry based proteomics technologies to decipher Ku70 biological functions We first improve the proteomics sample preparation method in order to enhance ... Silver staining of different amount of BSA picomol, 500 femtomol, 100 femtomol, 50 femtomol, 10 femtomol, femtomol to femtomol BSA (From left to rig...

Ngày tải lên: 04/10/2015, 15:46

... spectrum of BT5AA 56 Synthesis and mass spectrum of 2TAA 58 Synthesis and mass spectrum of 3TAA 59 Synthesis and mass spectrum of 5M2TAA 60 Synthesis and mass spectrum of ... from the ancient remains of marine plant and animal life under extreme heat and pressure in an anaerobic environment Depending on the composition of the organic material, varying proport...

Ngày tải lên: 13/05/2014, 14:01

... for a manufacturing company that aims to improve and enhance their manufacturing system and operations The major advantages of a Web- based Kanban system is the availability of visible and real-time ... withdrawal Kanban signal and place it in ‘on-hold’ status on Web- based Kanban screen [2] The withdrawal Kanban signal from Kanban screen will be translated...

Ngày tải lên: 04/10/2015, 15:45

... Figure Visualization of one-dimensional self-organizing map after clustering Visualization of one-dimensional self-organizing map after clustering 1D-SOM matrix after metabolite-based clustering ... metabolite-based clustering and visualization of large sets of metabolic marker candidates based on self-organizing maps (SOMs) Unlike applications of the class...

Ngày tải lên: 12/08/2014, 17:20

... article as: Kooren et al.: Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery Clinical Proteomics ... DeSouza LV, Matta A, Tripathi SC, Ghanny S, DattaGupta S, Thakar A, Chauhan SS, Siu KWM: iTRAQMultidimensional Liquid Chromatography and Tandem...

Ngày tải lên: 13/08/2014, 13:20

... biomarkers, and they participated in the data analyses AAH developed the customized Spotfire tool used for data analyses and reviewed statistical analyses YG participated in the assessment and ... assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood Journal of Translati...

Ngày tải lên: 18/06/2014, 16:20

... designed and managed the valuation survey, analysed and reported on the valuation data and contributed to the writing of the manuscript All authors read and approved the final manuscript Acknowledgements ... state Validation of the preference based CAMPHOR scale A majority (87.8%) of the 91 participants in the CAMPHOR validation survey were in New Y...

Ngày tải lên: 18/06/2014, 19:20

... CA1 CA MA1, SA MA, SA1 MA, SA MA, SA MA, SA Event +CA2 +SA +MA2 + SA2 +CA -SA -MA Result CA1 stop CA2 start CA → MA SA start MA1 stop MA2 start SA1 stop SA2 start MA stop SA stop CA start SA ... data from each case is transferred to a PC and evaluated statistically and graphically: the number of individual occurrences of each task, mean duration of each occurrence of each task,...

Ngày tải lên: 20/06/2014, 00:20

... receptor in MM Importantly their mass Page of 11 spectrometry approach demonstrated the potential for pharmacodynamic monitoring The future of mass spectrometry in biomarker discovery The use of mass ... this article as: Micallef et al., Applying mass spectrometry based proteomic technology to advance the understanding of multiple myeloma Journal o...

Ngày tải lên: 10/08/2014, 22:21

... (and Lys) tend to be over- High density IJISS DNA arrays have been developed for global analysis of Streptomyces gene expression and transcription factor binding The HspR regulatory system of S ... against the test arrays and the probe performance was scored using the following equations Firstly the Cy3 and Cy5 background-subtracted signals, designated 'g' an...

Ngày tải lên: 14/08/2014, 21:20

... substitution of poly(4-fluoro-2,5benzophenone) with various nucleophiles .7 1-4 Synthesis of functionalized polythiophenes 1-5 Synthesis of functionalized PLA and PCL 1-6 Synthesis ... 1-6 Synthesis of functional polyesters In the following chapters, the functionalized monomer approach is used to prepare functionalized diene-based materials Synthesis of a wide...

Ngày tải lên: 14/11/2014, 08:10

Ngày tải lên: 14/11/2014, 12:55

... of influenza A (H1N1) virus infection to explore the impact of influenza infection and inflammation on DNA damage and DNA damage responses By studying chromatin phosphorylation as a measure of DNA ... of DNA damage, we show that the level of DNA damage increases following influenza infection, and we provide data that supports a role for replication fork breakdow...

Ngày tải lên: 09/09/2015, 08:16

... αglucosidase and α-amylase can significantly reduce the post-prandial increase in blood glucose after a meal, with starch as the major calorie intake The apparent advantage of the starch hydrolase inhibitors ... linear range of gelatinized starch Table Accuracy and precision of the high- throughput method Table IC50 and acarbose equivalence of inhibitors obtaine...

Ngày tải lên: 10/09/2015, 09:01

... develop and apply computational methods and tools for ADR and toxicity prediction The methods developed in this work are potentially useful for development and application of QSAR models as well ... complex, time consuming and resource intensive Toxicity is one of the primary reasons for the failure of drug candidates in later stages of drug deve...

Ngày tải lên: 10/09/2015, 09:02