Molecular mechanism of self renewal exit during endothelial differentiation
Molecular mechanism of self renewal exit during endothelial differentiation
... MOLCULAR MECHANISM OF SELF- RENEWAL EXIT DURING ENDOTHELIAL DIFFERENTIATION QUE JIANWEN (B Med., China) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY OF MEDICINE DEPARTMENT OF SURGERY ... endocytosis of acetylated LDL To understand the molecular mechanism of endothelial differentiation, we began by investigating one aspect of endothelial diff...
Báo cáo khoa học: Transthyretin and familial amyloidotic polyneuropathy Recent progress in understanding the molecular mechanism of neurodegeneration pdf
... b-strands instead of eight, with the C and D strands and the intervening loop forming a large loop, exposing some hydrophobic residues in this region that are normally buried on the inside of the ... the protein [98] Dislocation of the C and D strands from their native edge region may result in the formation of a new interface involving A and B strands which...
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Báo cáo khoa học: Benzo[a]pyrene impairs b-adrenergic stimulation of adipose tissue lipolysis and causes weight gain in mice A novel molecular mechanism of toxicity for a common food pollutant doc
... the lack of a satiety signalling, whereas no change in food intake was detected in the B [a] P-treated animals In addition, the absolute values of leptin in control and B [a] P-treated animals were ... Results are shown as the average weight gain every days ± SEM rine-induced lipolysis Chronic (15 day) B [a] P exposure caused a significant weight gain and increa...
Báo cáo y học: "The molecular mechanism of osteoclastogenesis in rheumatoid arthritis" pptx
... spontaneously produced in organ cultures of synovial tissues derived from RA patients Addition of anti-inflammatory cytokines IL-4 and IL-13 completely inhibited the production of IL-17 in synovial ... by activated T cells was completely inhibited by adding OPG 284 Using an ELISA system, we measured the level of a soluble form of RANKL in the synovial fluids Concentrations of...
NVESTIGATING THE MOLECULAR MECHANISM OF PHOSPHOLAMBAN REGULATION OF THE Ca2+-PUMP OF CARDIAC SARCOPLASMIC RETICULUM
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ABSTRACT Brandy Lee Akin INVESTIGATING THE MOLECULAR MECHANISM OF PHOSPHOLAMBAN REGULATION OF THE Ca2+-PUMP OF CARDIAC ... back into the lumen of the SR by the Ca2+ pump, SERCA2a, making Ca2+ available for the next contraction (1) Therefore, the rate of Ca2+ transport by S...
The Molecular Mechanism of Break Induced Replication
... Disclaimer Title of Thesis/Dissertation: The Molecular Mechanism of Break Induced Replication For the degree of Master of Science Choose your degree I certify that in the preparation of this thesis, I ... The Molecular Mechanism of Break Induced Replication Major Professor: Anna Malkova DNA double strand break (DSB) is one of the most thre...
LIVE TRACKING VIRE2 PROTEIN AND MOLECULAR ANALYSIS OF YEAST FACTOR PMP3P DURING AGROBACTERIUM MEDIATED TRANSFORMATION
... LIVE- TRACKING VIRE2 PROTEIN AND MOLECULAR ANALYSIS OF YEAST FACTOR PMP3P DURING AGROBACTERIUM- MEDIATED TRANSFORMATION LI XIAOYANG (B Sc Science.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF ... Comparison of transient transformation, stable transformation and VirE2 delivery in AMT of yeast 67 IX LIST OF FIGURES Figure 3.1 Possible roles of...
UNDERSTANDING THE MOLECULAR MECHANISM OF CENTRINS IN TRYPANOSOMA BRUCEI
... molecular mechanisms of TbCentrin2 and TbCentrin4 in Trypanosoma brucei viii Centrins are EF-hand containing proteins that bind Ca2+ They are regulatory proteins functioning through specific binding ... database screening for T brucei proteins containing centrin binding motif initially characterized in Sfi1p have been used Centrins are proteins functioning through interactio...
Investigating the molecular mechanism of ERp29 regulated cell cycle arrest in breast cancer
... nodes behind the breastbone Or Inflammatory breast cancer is a rare type of breast cancer The breast looks red and swollen because cancer cells block the lymph vessels in the skin of the breast ... dissertation, the author attempt to investigate how ERp29 may regulate another effector of PERK, Nrf2 in breast cancer cell lines The levels of eIFα...
Tài liệu Báo cáo Y học: Phosphorylation of initiation factor-2a is required for activation of internal translation initiation during cell differentiation ppt
... differentiation, translation mediated by cellular IRES elements benefits from phosphorylation of eIF2a Supplementary mechanisms for inhibition of global protein synthesis, such as reduced availability of the ... is commonly regulated at the level of eIF2a phosphorylation [4,24], we wished to check the status of eIF2a phosphorylation in cells undergoing differentiation...
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... with the sequences of 1CEV and 1RLA and pasted into the structural alignment The alignment was then corrected by hand Since the sequences of the two arginases and agmatinase greately differ in the ... that the environment of tryptophan residues is essentially conserved in the mutant enzyme On the other hand, the absence of major differences in the CD...
Báo cáo khoa học: Molecular characterization of a novel nuclear transglutaminase that is expressed during starfish embryogenesis ppt
... ACATGTACATGTATATCACTTTGAACTGGTTTTCATTAAAAAAAAAAAACCATCAATTTG AGAAGAAACAATTACTTCTTAAGTCAATTAATTTTTCTAGAAATGCAAAAGATATTCCCC TTAACAGCTGTTTGAAATGAGGCCTCGGTCTCAAGTTTAAGAGTGCCCCCATATGTAAGC TAAAAAGCTCCAGGAAGTTGACCCAGAAGAAATTTGTTAAGAGTTCACGGATAAGCAAGG ... A H V T L N V K S A * ATGCGAGGTCAGCATTTATCCAACCAGAAGCTTCACGGAGCTAGCTGGGCAAGGAAATTT GATAATCGCAAGAAATAATTTCCCCCCAAAAACAAAAGGTTGTTGGCTGAAAATACTTCT...
Báo cáo khoa học: Molecular organization and force-generating mechanism of dynein pot
... structure and its force-generating mechanism A C reinhardtii axonemal dynein c Head ring Motor domain Linker #1 #2 Tail 1000 Fig Overview of the molecular organization of dynein (A) Linear map of the ... clarify the mechanism of the coordination, modulating the tail domain could be one of the mechanisms of regulation of dynein motility [94] In addition, dynein...
Morphology and growth mechanism study of self assembled silicon nanowires synthesized by thermal evaporation
... [10±13] and thermal evaporation [14±17] are two methods normally used for the synthesis of SiNWs The key point in these two methods is the formation of a sucient amount of silicon atoms and/ or silicon ... made of a Si core and a SiO2 sheath The one-dimensional growth of SiNWs is facilitated by the SiO2 sheath that con®nes the lateral growth of SiNWs, and the...
Báo cáo khoa học: Ribonuclease H: molecular diversities, substrate binding domains, and catalytic mechanism of the prokaryotic enzymes ppt
... sites of these enzymes, these enzymes may also share a catalytic mechanism with RNase H Substrate recognition mechanism of RNase H The crystal structure of human RNase H1 in complex with the substrate ... activity, because the number of the metal -binding sites found in the crystal structures of the enzyme–metal ion complex formed in the absence of the...
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