Novel chiral stationary phase for the enantioseparation of racemic drugs 2
Novel chiral stationary phase for the enantioseparation of racemic drugs 2
... 1 .22 1 .24 1. 12 1.33 1.56 0.93 3C6C11C- 2. 58 4 .21 1.46 3.63 5.83 1.75 1.40 1.44 1 .20 2. 17 2. 25 1.13 3C6C11C- 6.50 9.57 4.18 8 .29 12. 45 5.31 1 .28 1.30 1 .27 1.68 1.71 1.70 3C6C11C- 3. 92 5.83 2. 35 ... 13.08 27 .69 8.79 1.44 1.53 1.30 3 .26 2. 69 1.81 3C6C11C- 2. 42 4.50 1.50 1.53 1.57 1 .29 2. 80 2. 46 1.05 3C6C11C- 16.50 28 .00 9.67 21 .50 34 .22 11.33 1.30 1. 72 1.1...
Ngày tải lên: 16/09/2015, 17:14
Novel chiral stationary phase for the enantioseparation of racemic drugs 1
... Experimental 13 9 7 .1 General 14 0 7 .1. 1 Materials 14 0 7 .1. 2 Instrumentation 14 0 7 .1. 3 Packing of CSPs 14 1 7 .1. 4 HPLC Instrumentation 14 1 7 .1. 5 Basic Chromatography Parameters 14 2 7.2 Preparation of Ether-linkage ... Conclusion 10 3 References 10 5 Chapter Effects of Spacer Length 10 6 iv 5 .1 Introduction 10 7 5.2 Normal Phase 10 9 5.3 Reversed Phase...
Ngày tải lên: 16/09/2015, 17:13
Development of novel chiral stationary phases for HPLC based on covalently bonded polysaccharide derivatives
... DEVELOPMENT OF NOVEL CHIRAL STATIONARY PHASES FOR HPLC BASED ON COVALENTLY BONDED POLYSACCHARIDE DERIVATIVES ZHANG SHENG (B.Sc., Peking University) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... chloroform-containing, dichloromethane-containing, tetrahydrofurancontaining mobile phases, as well as standard IPA-hexane mobile phases vii List of Tables Table...
Ngày tải lên: 14/09/2015, 08:40
design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of chagas
... Evaluation of New Anti-cancer Nitrogen-Containing Combretastatins and Novel Cysteine Protease Inhibitors for the Treatment of Chagas Rogelio Siles Mentor: Kevin G Pinney, Ph.D In an effort to combat ... Derivatives of Combretastatins A-1 and A-4 66 Synthesis of Cold Precursors of Radio-labeled Combretastatins CA-1 and CA-4 70 Synthesis of OXi800...
Ngày tải lên: 14/11/2014, 11:32
Liquid phase microextraction for the determination of acidic drugs and beta blockers in water samples
... LIQUID- PHASE MICROEXTRACTION FOR THE DETERMINATION OF ACIDIC DRUGS AND β -BLOCKERS IN WATER SAMPLES EE KIM HUEY (B.Sc (Hons.), NUS) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF SCIENCE ... thanks to Xiaofeng for her insight to the project; Junie for proofreading this thesis; Elaine and Debbie for their friendship during the course of this pro...
Ngày tải lên: 10/11/2015, 11:00
Chiral enantioseparation of racemic drugs
... influence of changing pH of the buffer and mobile phase composition on enantioseparation of several racemic drugs and compounds viii were also examined using a permethylated CD CSP based on the chiral ... toluene / ∆ Scheme 35 1.12 Racemic Drugs and Compounds The chief aim in this thesis, after the synthesis of the novel CSPs, is targeted towards the enantioseparation o...
Ngày tải lên: 12/09/2015, 10:17
2D optical trapping potential for the confinement of heteronuclear molecules 2
... coefficient of the trapped LiK molecules in the 2D dynamics of the optical lattice The loss rate due to the reaction is the product of this rate coefficient and the 2D density of the trapped ... and the optical lattice, we obtain: 2 ωz,ol lc,g = = lc,ol ωz,g 8U0 m 2 2U0 mzR = 4π zR 4π w 02 = λ 2 (2. 3. 12) The typical waist size of the beam used i...
Ngày tải lên: 30/09/2015, 10:13
Novel chiral stationary phases (CSP) for enantioseparation processes
... NOVEL CHIRAL STATIONARY PHASES (CSP) FOR ENANTIOSEPARATION PROCESSES CHEN LEI (MSc) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHYLOSORPHY DEPARTMENT ... chromatographic techniques Enantioseparation by HPLC includes two major parts: chiral stationary phases (CSPs) and chiral mobile phase additives (CMPAs) 1.3.1 Chiral stationary phases (CSPs) Chiral H...
Ngày tải lên: 17/09/2015, 17:18
Báo cáo y học: "Endoscopic Facet Debridement for the treatment of facet arthritic pain – a novel new technique
... low back pain Pain Physician 1999;2:59-64 Manchikanti L, Pampati V, Fellows B, et al The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents ... men; mean age 64, range 22-89) were included Length of follow-up was at least years with a maximum of years Location of facet pain was cervical in 45, thoracic in 15, and lu...
Ngày tải lên: 26/10/2012, 09:32
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... metacleavage pathway of 2-aminophenol in Pseudomonas sp strain AP-3 (A) Proposed pathway of 4-amino-3-hydroxybenzoic acid in Bordetella sp strain 10d (10) I, 4-amino-3hydroxybenzoic acid; II, 2-amino-5carboxymuconic ... of a mutant, strain Y-2, of the aniline-assimilating Pseudomonas sp strain AW-2 [20] Results Spectral changes during metabolism of 4-amino...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Novel Design of an Integrated Pulp Mill Biorefinery for the Production of Biofuels for Transportation pot
... paper mill, there is a large steam and electricity demand at the pulp mill To simplify calculations, we decided to use only a pulp mill rather than an integrated pulp and paper mill As a result, the ... From the calculations derived in Appendix A, the energy demand for the modified pulping section of the plant is 56 MW of electricity and 267 tonnes per day...
Ngày tải lên: 26/02/2014, 14:20
Báo cáo khoa học: A novel metallobridged bis(b-cyclodextrin)s fluorescent probe for the determination of glutathione doc
... of glutathione and glutathione disulde in human plasma and tobacco leaves by capillary electrophoresis with laser-induced uorescence detection Talanta 65, 986990 Svardal AM, Mansoor MA & Ueland ... curve and the regression equation The average recovery test was made using the standard addition method, and the RSD was generally good when obtained from a series of six plasma s...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot
... Non-activated meprin In total Activated meprin Non-activated meprin In total Activated meprin Non-activated meprin In total Activated meprin Non-activated meprin In total 1 2 3 4 All All All ... that hmeprin has activity similar to BMP-1 ⁄ TLD-like metalloendopeptidases in that it acts as a procollagen C protease as well as an activator of lysyl oxidase Therefore, an impor...
Ngày tải lên: 07/03/2014, 06:20
novel semiconductor materials for the development of
... CHEMFET of BIOFET In all of these devices, the surface potential developed at the surface of the semiconductor is based on the direct interaction of the ligand with the exposed atoms of the semiconductor, ... maturation with the commercialization of these pH sensors in the mid-80’s, while they were the platform for the development of other ion-select...
Ngày tải lên: 20/03/2014, 13:05
solvothermal reactions- an original route for the synthesis of novel materials
... synthesis of novel materials and the development of new processes Solvothermal synthesis of novel materials Roy has described the challenge for synthesizing new materials to specification [32] Hydro- and ... Conclusion Solvothermal reactions appear to be important for either the synthesis of novel materials, the preparation of nanostructured particl...
Ngày tải lên: 20/03/2014, 13:08