Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system
Development of hybrid promoters and viral vectors for improved gene delivery to the central nervous system
... overview of the progress made by using different types of promoters and vectors for gene delivery to the CNS 1.1 Current progress in gene therapy Gene therapy, which usually refers to somatic gene therapy, ... by the selection of promoters The gene delivery vector that carries and transfers the gene into the nuclei of target cell is another...
Ngày tải lên: 16/09/2015, 08:30
Genetic engineering and surface modification of baculovirus derived vectors for improved gene delivery to the central nervous system
... GENETIC ENGINEERING AND SURFACE MODIFICATION OF BACULOVIRUS DERIVED VECTORS FOR IMPROVED GENE DELIVERY TO THE CENTRAL NERVOUS SYSTEM YANG YI (B Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR ... Chapter Three: Genetic Engineering of Baculovirus Vectors for Controlled Gene Delivery ………65 3.1 Introduction………………………………………………………………… 66 3....
Ngày tải lên: 14/09/2015, 11:28
Design of viral vectors for improved gene delivery
... Packaging of amplicon viral vectors 3.3.10 Analysis of cell cycle-dependent transgene expression in pC8-36 amplicon viral vectors 3.3.11 Effect of transduction of viral vector on the cell cycle profile ... (Castro et al., 2003a) 1.3.2 Gene therapy of gliomas One of the formidable tasks of intracranial gene delivery is the difficulty in achieving gene delivery...
Ngày tải lên: 16/09/2015, 15:54
Báo cáo khoa học: "Genomic variability in Potato virus M and the development of RT-PCR and RFLP procedures for the detection of this virus in seed potatoes" ppt
... doi:10.1186/1743-422X-7-25 Cite this article as: Xu et al.: Genomic variability in Potato virus M and the development of RT-PCR and RFLP procedures for the detection of this virus in seed potatoes Virology ... detected in several potato samples from an experimental farm in the province of Page of Figure Sensitivity of RT-PCR using pr...
Ngày tải lên: 12/08/2014, 04:21
RESEARCH ON THE GROWTH AND DEVELOPMENT OF TARO VARIETIES AND CULTIVATION TECHNIQUES FOR THE POTENTIAL VARIETY IN YEN BAI PROVINCE
... activities of study and evaluating the growth and development of some taro varieties on single-crop-land and lowland in Yen Bai province, finding out the most potential and suitable variety for the ... implemented the study titled "Research on the growth and development of taro varieties and cultivation techniques for the...
Ngày tải lên: 06/10/2014, 11:46
Báo cáo hóa học: " Research Article Binocular Image Sequence Analysis: Integration of Stereo Disparity and Optic Flow for Improved Obstacle Detection and Tracking" pptx
... calculate the optic flows for the left and right image sequences 2.1 Optic flows of moving obstacles Many approaches have been designed for obtaining optic flows for moving objects from image sequences ... “Cooperative integration of stereopsis and optical flow computation,” Journal of the Optical Society of America A, vol 12, no 12, pp 2564–2572, 1995 [14] S P Cliffo...
Ngày tải lên: 21/06/2014, 22:20
báo cáo khoa học:" Development of a patient reported outcome scale for fatigue in multiple sclerosis: The Neurological Fatigue Index (NFI-MS)" pptx
... phase of measurement, with the aim of developing a valid and reliable patient reported outcome scale for fatigue, the Neurological Fatigue Index (NFIMS) The items in the scale are based on the ... the notion that the sub-dimensions were part of a single, supraordinate theme of neurological fatigue Fit of scale data to the Rasch model also...
Ngày tải lên: 12/08/2014, 01:21
An investigation into students’ conversational needs and some suggestions for a speaking syllabus to the 2nd year english bachel
... designing a syllabus are illustrated as follows Needs analysis-Objectives and aims-Sequencing–Teaching method–Testing and evaluation As a result, analyzing the needs of learners is the first and the foremost ... able to learn the foreign language as a means for close communication and acceptance by people who speak it Learners with instrumental motivation may l...
Ngày tải lên: 07/09/2013, 13:19
báo cáo hóa học: " Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE" pptx
... cells in defined lesional stages Quantification of CCR1, CCR2 and CCR5 mRNA expressing Quantification of CCR1, CCR2 and CCR5 mRNA expressing cells in defined lesional stages Mean numbers of CCR1+ ... expression of CCR1, CCR2 and CCR5 in the spinal cord (data not shown) Enhanced expression of CCR1, CCR2 and CCR5 mRNA was subsequently observ...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: "Immunohistochemical study of constitutive neuronal and inducible nitric oxide synthase in the central nervous system of goat with natural listeriosis" potx
... counterstained with hematoxylin Magnification A and B, ×66 C and D, ×132 Immunohistochmical study of nitric oxide synthase in the central nervous system of goat Enhanced expression of nNOS and iNOS in ... is the first study of NOS expression in the goat brain with listeriosis The involvement of iNOS in bovine and caprine listeriosis h...
Ngày tải lên: 07/08/2014, 14:23
báo cáo khoa học: "Isolated angiitis of the central nervous system with tumor-like lesion, mimicking brain malignant glioma: a case report and review of the literature" pdf
... Primary angiitis of the central nervous system: serial MRI of brain and spinal cord Neuroradiology 2001, 43:599-607 14 Moore PM: Diagnosis and management of isolated angiitis of the central nervous ... Neuropsychopharmacol Biol Psychiatry 2005, 29:627-631 Carandang C, Grant A: Delirium and Isolated Angiitis of the Central Nervous System: a Case...
Ngày tải lên: 09/08/2014, 02:20
williams - uncontrolled risk; the lessons of lehman brothers and how systemic risk can still bring down the world financial system (2010)
... UNCONTROLLED RISK THE LESSONS OF LEHMAN BROTHERS AND HOW SYSTEMIC RISK CAN STILL BRING DOWN THE WORLD FINANCIAL SYSTEM M A R K T W I L L I A M S New York ... the prosperity of H Lehman 10 Uncontrolled Risk The arrival of Mayer reunited all the brothers In acknowledgment of Mayer’s arrival in 1850, the name of the family busines...
Ngày tải lên: 01/11/2014, 23:33
Bio nanoparticles and bio microfibers for improved gene transfer into glioma cells
... BIO- NANOPARTICLES AND BIO- MICROFIBERS FOR IMPROVED GENE TRANSFER INTO GLIOMA CELLS YANG JINGYE (B Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY NUS GRADUATE SCHOOL FOR INTEGRATIVE ... procedures to form bio- nanoparticles and bio- microfibers The findings in this study should enrich the development of gene therapies for CNS diseases, p...
Ngày tải lên: 12/09/2015, 09:10
Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
... vulnerable, population of patients Chemotherapy- induced cognitive decline in the absence of radiation The best data on the cognitive effects of chemotherapy alone have come from studies of children with ... high doses of chemotherapy is clearly demonstrated by Noble and colleagues [1], yet these proposed studies not take into consideration the possible effects o...
Ngày tải lên: 06/08/2014, 18:21